positive regulation of proteasomal ubiquitin-dependent protein catabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. (Gene Ontology, GO_0032436)
External Link http://amigo.geneontology.org/amigo/term/GO:0032436
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Genes

55 genes participating in the positive regulation of proteasomal ubiquitin-dependent protein catabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AURKA aurora kinase A
AXIN1 axin 1
BBS7 Bardet-Biedl syndrome 7
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLU clusterin
CSNK1D casein kinase 1, delta
CUL3 cullin 3
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DTHD1 death domain containing 1
DVL1 dishevelled segment polarity protein 1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FBXO22 F-box protein 22
GCLC glutamate-cysteine ligase, catalytic subunit
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GSK3B glycogen synthase kinase 3 beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IL33 interleukin 33
KEAP1 kelch-like ECH-associated protein 1
LRRK2 leucine-rich repeat kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NKD2 naked cuticle homolog 2 (Drosophila)
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NUB1 negative regulator of ubiquitin-like proteins 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PIAS1 protein inhibitor of activated STAT, 1
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PRICKLE1 prickle homolog 1 (Drosophila)
PSEN1 presenilin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RNF180 ring finger protein 180
SIRT2 sirtuin 2
SMAD7 SMAD family member 7
SMC5 structural maintenance of chromosomes 5
SOCS4 suppressor of cytokine signaling 4
SOCS5 suppressor of cytokine signaling 5
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VCP valosin containing protein
ZFAND2A zinc finger, AN1-type domain 2A