positive regulation of defense response Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of a defense response. (Gene Ontology, GO_0031349)
External Link http://amigo.geneontology.org/amigo/term/GO:0031349
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Genes

270 genes participating in the positive regulation of defense response biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIM2 absent in melanoma 2
ANKRD17 ankyrin repeat domain 17
ANKRD42 ankyrin repeat domain 42
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
BCL10 B-cell CLL/lymphoma 10
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BTK Bruton agammaglobulinemia tyrosine kinase
C3 complement component 3
CADM1 cell adhesion molecule 1
CARD9 caspase recruitment domain family, member 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL24 chemokine (C-C motif) ligand 24
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD1D CD1d molecule
CD226 CD226 molecule
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD47 CD47 molecule
CD86 CD86 molecule
CDK1 cyclin-dependent kinase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC7A C-type lectin domain family 7, member A
CLOCK clock circadian regulator
CNPY3 canopy FGF signaling regulator 3
CNR1 cannabinoid receptor 1 (brain)
COCH cochlin
COLEC12 collectin sub-family member 12
CREB1 cAMP responsive element binding protein 1
CREB3L3 cAMP responsive element binding protein 3-like 3
CRH corticotropin releasing hormone
CRTAM cytotoxic and regulatory T cell molecule
CTSB cathepsin B
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DMBT1 deleted in malignant brain tumors 1
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
EDNRA endothelin receptor type A
EGFR epidermal growth factor receptor
ELK1 ELK1, member of ETS oncogene family
EREG epiregulin
F12 coagulation factor XII (Hageman factor)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FADD Fas (TNFRSF6)-associated via death domain
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FFAR2 free fatty acid receptor 2
FFAR3 free fatty acid receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
GJA1 gap junction protein, alpha 1, 43kDa
GPRC5B G protein-coupled receptor, class C, group 5, member B
HCK HCK proto-oncogene, Src family tyrosine kinase
HLA-E major histocompatibility complex, class I, E
HPX hemopexin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HYAL2 hyaluronoglucosaminidase 2
IDO1 indoleamine 2,3-dioxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFIH1 interferon induced with helicase C domain 1
IFNB1 interferon, beta 1, fibroblast
IFNK interferon, kappa
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL12A interleukin 12A
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL17B interleukin 17B
IL17C interleukin 17C
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RC interleukin 17 receptor C
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL2 interleukin 2
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL33 interleukin 33
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ITCH itchy E3 ubiquitin protein ligase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LAG3 lymphocyte-activation gene 3
LAMP1 lysosomal-associated membrane protein 1
LBP lipopolysaccharide binding protein
LGMN legumain
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LTA lymphotoxin alpha
LY96 lymphocyte antigen 96
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MAVS mitochondrial antiviral signaling protein
MB21D1 Mab-21 domain containing 1
MED1 mediator complex subunit 1
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MMP2 matrix metallopeptidase 2
MYD88 myeloid differentiation primary response 88
NCR3 natural cytotoxicity triggering receptor 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLRC4 NLR family, CARD domain containing 4
NLRC5 NLR family, CARD domain containing 5
NLRP12 NLR family, pyrin domain containing 12
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPY5R neuropeptide Y receptor Y5
OSM oncostatin M
OSMR oncostatin M receptor
OTULIN OTU deubiquitinase with linear linkage specificity
PDE2A phosphodiesterase 2A, cGMP-stimulated
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLSCR1 phospholipid scramblase 1
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PVR poliovirus receptor
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PYCARD PYD and CARD domain containing
REG3G regenerating islet-derived 3 gamma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFTN1 raftlin, lipid raft linker 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RPS19 ribosomal protein S19
RPS27A ribosomal protein S27a
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A12 S100 calcium binding protein A12
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SARM1 sterile alpha and TIR motif containing 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SIN3A SIN3 transcription regulator family member A
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SNX4 sorting nexin 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAC1 tachykinin, precursor 1
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM173 transmembrane protein 173
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TNIP3 TNFAIP3 interacting protein 3
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIL TLR4 interactor with leucine-rich repeats
TRIM15 tripartite motif containing 15
TRIM5 tripartite motif containing 5
TXK TXK tyrosine kinase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2N ubiquitin-conjugating enzyme E2N
UCN urocortin
UNC93B1 unc-93 homolog B1 (C. elegans)
USP17L2 ubiquitin specific peptidase 17-like family member 2
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
WNT5A wingless-type MMTV integration site family, member 5A
ZBP1 Z-DNA binding protein 1
ZP3 zona pellucida glycoprotein 3 (sperm receptor)