positive regulation of apoptotic signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. (Gene Ontology, GO_2001235)
External Link http://amigo.geneontology.org/amigo/term/GO:2001235
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Genes

168 genes participating in the positive regulation of apoptotic signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR2 angiotensin II receptor, type 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
APAF1 apoptotic peptidase activating factor 1
APOPT1 apoptogenic 1, mitochondrial
ATPIF1 ATPase inhibitory factor 1
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCAP31 B-cell receptor-associated protein 31
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCLAF1 BCL2-associated transcription factor 1
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BMF Bcl2 modifying factor
BMPR1B bone morphogenetic protein receptor, type IB
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CIDEB cell death-inducing DFFA-like effector b
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSC cathepsin C
CTSH cathepsin H
CYLD cylindromatosis (turban tumor syndrome)
DAB2IP DAB2 interacting protein
DAPK3 death-associated protein kinase 3
DAXX death-domain associated protein
DDIT3 DNA-damage-inducible transcript 3
DEDD2 death effector domain containing 2
DFNA5 deafness, autosomal dominant 5
DNM1L dynamin 1-like
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
E2F1 E2F transcription factor 1
EI24 etoposide induced 2.4
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FAM162A family with sequence similarity 162, member A
FAS Fas cell surface death receptor
FBXO18 F-box protein, helicase, 18
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
G0S2 G0/G1 switch 2
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPER1 G protein-coupled estrogen receptor 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HRK harakiri, BCL2 interacting protein
HTRA2 HtrA serine peptidase 2
HYAL2 hyaluronoglucosaminidase 2
IFNB1 interferon, beta 1, fibroblast
IL19 interleukin 19
IL20RA interleukin 20 receptor, alpha
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
ING5 inhibitor of growth family, member 5
INHBA inhibin, beta A
INHBB inhibin, beta B
ITM2C integral membrane protein 2C
JAK2 Janus kinase 2
JAK3 Janus kinase 3
LCK LCK proto-oncogene, Src family tyrosine kinase
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAGED1 melanoma antigen family D1
MAL mal, T-cell differentiation protein
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MCL1 myeloid cell leukemia 1
MFF mitochondrial fission factor
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
MOAP1 modulator of apoptosis 1
MSX1 msh homeobox 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCK1 NCK adaptor protein 1
NF1 neurofibromin 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NGFR nerve growth factor receptor
NKX3-1 NK3 homeobox 1
NMT1 N-myristoyltransferase 1
NOX1 NADPH oxidase 1
OSM oncostatin M
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD5 programmed cell death 5
PDCD7 programmed cell death 7
PDIA3 protein disulfide isomerase family A, member 3
PEA15 phosphoprotein enriched in astrocytes 15
PIAS4 protein inhibitor of activated STAT, 4
PIDD1 p53-induced death domain protein 1
PINK1 PTEN induced putative kinase 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAGL2 pleiomorphic adenoma gene-like 2
PLAUR plasminogen activator, urokinase receptor
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPIF peptidylprolyl isomerase F
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKCD protein kinase C, delta
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PYCARD PYD and CARD domain containing
RAD9A RAD9 homolog A (S. pombe)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RET ret proto-oncogene
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RPS3 ribosomal protein S3
RUNX3 runt-related transcription factor 3
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEPT4 septin 4
SERINC3 serine incorporator 3
SFN stratifin
SFPQ splicing factor proline/glutamine-rich
SFRP1 secreted frizzled-related protein 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SKIL SKI-like proto-oncogene
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD3 SMAD family member 3
SOD1 superoxide dismutase 1, soluble
SPOP speckle-type POZ protein
SRPX sushi-repeat containing protein, X-linked
STEAP3 STEAP family member 3, metalloreductase
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP1 transcription factor Dp-1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPD52L1 tumor protein D52-like 1
TRAF2 TNF receptor-associated factor 2
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIM39 tripartite motif containing 39
TRPS1 trichorhinophalangeal syndrome I
UBB ubiquitin B
WWOX WW domain containing oxidoreductase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF205 zinc finger protein 205
ZSWIM2 zinc finger, SWIM-type containing 2