portal hypertension Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

194 genes co-occuring with the disease portal hypertension in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ALB albumin 1.94689
EVL Enah/Vasp-like 1.71043
F2 coagulation factor II (thrombin) 1.67141
SST somatostatin 1.66555
NOS3 nitric oxide synthase 3 (endothelial cell) 1.65655
EDN1 endothelin 1 1.47725
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.35768
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.34243
ALPPL2 alkaline phosphatase, placental-like 2 1.31843
ALPP alkaline phosphatase, placental 1.31755
ALPL alkaline phosphatase, liver/bone/kidney 1.31712
GCG glucagon 1.2765
UTS2 urotensin 2 1.24385
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.23386
REN renin 1.22735
EDNRA endothelin receptor type A 0.955361
AVP arginine vasopressin 0.949936
HMOX1 heme oxygenase 1 0.949519
GGT1 gamma-glutamyltransferase 1 0.944106
THPO thrombopoietin 0.905265
F5 coagulation factor V (proaccelerin, labile factor) 0.901978
AFP alpha-fetoprotein 0.869187
MSN moesin 0.86714
UTS2R urotensin 2 receptor 0.826178
RAB3D RAB3D, member RAS oncogene family 0.825358
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 0.813462
NOSIP nitric oxide synthase interacting protein 0.799923
EDNRB endothelin receptor type B 0.774523
PGF placental growth factor 0.735838
MLX MLX, MAX dimerization protein 0.733001
PROS1 protein S (alpha) 0.728547
TGFB1 transforming growth factor, beta 1 0.722077
SLC22A20 solute carrier family 22, member 20 0.712392
NPR1 natriuretic peptide receptor 1 0.71078
GUCY2C guanylate cyclase 2C 0.709975
TNF tumor necrosis factor 0.709169
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.709169
LBP lipopolysaccharide binding protein 0.703134
FBL fibrillarin 0.678302
TIMP1 TIMP metallopeptidase inhibitor 1 0.677903
CNR1 cannabinoid receptor 1 (brain) 0.676308
INS insulin 0.66596
NOS1 nitric oxide synthase 1 (neuronal) 0.653276
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.640645
F3 coagulation factor III (thromboplastin, tissue factor) 0.632777
CD79A CD79a molecule, immunoglobulin-associated alpha 0.624535
FBLL1 fibrillarin-like 1 0.620226
MUCL1 mucin-like 1 0.616312
FN1 fibronectin 1 0.606933
CTGF connective tissue growth factor 0.603811
GGT2 gamma-glutamyltransferase 2 0.58433
SAA1 serum amyloid A1 0.583941
PRKCSH protein kinase C substrate 80K-H 0.583552
HBA2 hemoglobin, alpha 2 0.581606
F8 coagulation factor VIII, procoagulant component 0.56722
VEGFA vascular endothelial growth factor A 0.565666
APLNR apelin receptor 0.545093
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.545093
NOSTRIN nitric oxide synthase trafficking 0.543155
VWF von Willebrand factor 0.542379
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.539667
PTPRE protein tyrosine phosphatase, receptor type, E 0.53928
HBA1 hemoglobin, alpha 1 0.535409
KLF2 Kruppel-like factor 2 0.535409
GAST gastrin 0.52536
LIN9 lin-9 DREAM MuvB core complex component 0.517265
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.511496
BCHE butyrylcholinesterase 0.511496
ACER3 alkaline ceramidase 3 0.503441
ACE angiotensin I converting enzyme 0.503058
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.498467
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.481325
JAK2 Janus kinase 2 0.476014
IL6 interleukin 6 0.468819
CAV1 caveolin 1, caveolae protein, 22kDa 0.458241
ARRB2 arrestin, beta 2 0.451078
PCNA proliferating cell nuclear antigen 0.449571
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.44129
NOS2 nitric oxide synthase 2, inducible 0.427015
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.424765
ANGPT1 angiopoietin 1 0.410909
HAVCR2 hepatitis A virus cellular receptor 2 0.406798
KNG1 kininogen 1 0.406051
APEH acylaminoacyl-peptide hydrolase 0.404931
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.404557
LCOR ligand dependent nuclear receptor corepressor 0.401572
CAT catalase 0.398589
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.393374
TPMT thiopurine S-methyltransferase 0.389653
TIMP2 TIMP metallopeptidase inhibitor 2 0.389653
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.387794
NPPA natriuretic peptide A 0.385193
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.384079
CD4 CD4 molecule 0.381481
MARS methionyl-tRNA synthetase 0.371847
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.369997
SOD2 superoxide dismutase 2, mitochondrial 0.368888
JMJD6 jumonji domain containing 6 0.363716
CALCA calcitonin-related polypeptide alpha 0.36187
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.361502
TBXAS1 thromboxane A synthase 1 (platelet) 0.358551
RPAP3 RNA polymerase II associated protein 3 0.355235
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 0.345675
MMP9 matrix metallopeptidase 9 0.344574
PRMT1 protein arginine methyltransferase 1 0.344574
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.342739
PDE5A phosphodiesterase 5A, cGMP-specific 0.33944
ACVRL1 activin A receptor type II-like 1 0.327375
APLN apelin 0.326281
AQP1 aquaporin 1 (Colton blood group) 0.320454
TRA2B transformer 2 beta homolog (Drosophila) 0.313915
ASGR2 asialoglycoprotein receptor 2 0.309928
NLRP6 NLR family, pyrin domain containing 6 0.309928
ERAS ES cell expressed Ras 0.307395
PRB3 proline-rich protein BstNI subfamily 3 0.307395
CD163 CD163 molecule 0.303059
IFNA1 interferon, alpha 1 0.302698
MAOA monoamine oxidase A 0.301254
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.295851
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.294772
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.294413
ASGR1 asialoglycoprotein receptor 1 0.294413
IL1B interleukin 1, beta 0.292975
PGA4 pepsinogen 4, group I (pepsinogen A) 0.289027
PGA3 pepsinogen 3, group I (pepsinogen A) 0.289027
CTH cystathionine gamma-lyase 0.281868
GJA4 gap junction protein, alpha 4, 37kDa 0.279367
LECT2 leukocyte cell-derived chemotaxin 2 0.270819
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.268687
HFE hemochromatosis 0.268687
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.266913
MMP2 matrix metallopeptidase 2 0.266203
CD34 CD34 molecule 0.254888
SEPT7 septin 7 0.248905
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.24715
IGF1 insulin-like growth factor 1 (somatomedin C) 0.246799
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.245396
CRP C-reactive protein, pentraxin-related 0.241196
EPHB4 EPH receptor B4 0.238752
GPX5 glutathione peroxidase 5 0.238752
NT5E 5'-nucleotidase, ecto (CD73) 0.237706
GPX4 glutathione peroxidase 4 0.235964
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.227297
RELT RELT tumor necrosis factor receptor 0.226607
LARS leucyl-tRNA synthetase 0.225917
RXFP1 relaxin/insulin-like family peptide receptor 1 0.225917
NPY neuropeptide Y 0.224884
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.222822
STPG1 sperm-tail PG-rich repeat containing 1 0.222822
EFNB2 ephrin-B2 0.221793
GPX1 glutathione peroxidase 1 0.221793
MYLK3 myosin light chain kinase 3 0.22145
HRH2 histamine receptor H2 0.22145
PLAT plasminogen activator, tissue 0.220424
ADM adrenomedullin 0.220424
PDE9A phosphodiesterase 9A 0.219398
F13A1 coagulation factor XIII, A1 polypeptide 0.214297
IFT122 intraflagellar transport 122 0.210925
FBXO2 F-box protein 2 0.204593
CNR2 cannabinoid receptor 2 (macrophage) 0.204263
WT1 Wilms tumor 1 0.201962
TBX22 T-box 22 0.198386
S1PR2 sphingosine-1-phosphate receptor 2 0.19742
LEP leptin 0.19742
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.191408
GPR135 G protein-coupled receptor 135 0.191097
ABHD5 abhydrolase domain containing 5 0.188938
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.187415
XDH xanthine dehydrogenase 0.186811
VASH1 vasohibin 1 0.185612
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.183541
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.183248
ARRB1 arrestin, beta 1 0.183248
SRCIN1 SRC kinase signaling inhibitor 1 0.182375
WRNIP1 Werner helicase interacting protein 1 0.179239
IFNGR1 interferon gamma receptor 1 0.175679
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.175146
NPPC natriuretic peptide C 0.172544
XPR1 xenotropic and polytropic retrovirus receptor 1 0.170299
TUBGCP4 tubulin, gamma complex associated protein 4 0.168381
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.168148
GSTA3 glutathione S-transferase alpha 3 0.166095
ARG1 arginase 1 0.165874
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.165655
GSTA2 glutathione S-transferase alpha 2 0.165435
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.165217
MEOX2 mesenchyme homeobox 2 0.164786
GSTA4 glutathione S-transferase alpha 4 0.164786
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.163111
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.163111
GSTA1 glutathione S-transferase alpha 1 0.161523
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.159838
KRT18 keratin 18, type I 0.159302
PLG plasminogen 0.158605