polydactyly Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

255 genes co-occuring with the disease polydactyly in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GLI3 GLI family zinc finger 3 2.65816
LMBR1 limb development membrane protein 1 2.4779
MKKS McKusick-Kaufman syndrome 2.41653
SHH sonic hedgehog 2.40002
BBS1 Bardet-Biedl syndrome 1 2.22392
EVC Ellis van Creveld protein 2.20736
MKS1 Meckel syndrome, type 1 2.16289
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.07945
BBS4 Bardet-Biedl syndrome 4 2.06714
BBS2 Bardet-Biedl syndrome 2 1.95488
EVC2 Ellis van Creveld syndrome 2 1.93374
TMEM216 transmembrane protein 216 1.92482
HOXD13 homeobox D13 1.86552
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 1.82323
IFT80 intraflagellar transport 80 1.81284
BBS12 Bardet-Biedl syndrome 12 1.79841
ARL6 ADP-ribosylation factor-like 6 1.79616
BBS7 Bardet-Biedl syndrome 7 1.78759
TTC8 tetratricopeptide repeat domain 8 1.76683
TMEM67 transmembrane protein 67 1.72639
BBS10 Bardet-Biedl syndrome 10 1.68453
ALX4 ALX homeobox 4 1.64891
BBS5 Bardet-Biedl syndrome 5 1.64532
CC2D2A coiled-coil and C2 domain containing 2A 1.6247
HOXD11 homeobox D11 1.55336
GLI2 GLI family zinc finger 2 1.55291
CEP290 centrosomal protein 290kDa 1.53348
HOXD12 homeobox D12 1.52424
FGF4 fibroblast growth factor 4 1.49306
NEK1 NIMA-related kinase 1 1.46891
OFD1 oral-facial-digital syndrome 1 1.43815
B9D1 B9 protein domain 1 1.41753
ARL13B ADP-ribosylation factor-like 13B 1.41227
TMEM231 transmembrane protein 231 1.38472
RNF32 ring finger protein 32 1.3494
GLI1 GLI family zinc finger 1 1.33109
WDR35 WD repeat domain 35 1.32978
C2CD3 C2 calcium-dependent domain containing 3 1.32323
WDR19 WD repeat domain 19 1.30925
SALL1 spalt-like transcription factor 1 1.2909
HAND2 heart and neural crest derivatives expressed 2 1.28959
PTCH1 patched 1 1.24515
TCTN3 tectonic family member 3 1.23777
LZTFL1 leucine zipper transcription factor-like 1 1.22952
B9D2 B9 protein domain 2 1.21782
C8ORF37 chromosome 8 open reading frame 37 1.20526
BMP4 bone morphogenetic protein 4 1.19877
ALX3 ALX homeobox 3 1.19273
FGF8 fibroblast growth factor 8 (androgen-induced) 1.17121
AHI1 Abelson helper integration site 1 1.15666
IHH indian hedgehog 1.13459
RIMS4 regulating synaptic membrane exocytosis 4 1.13374
KIF7 kinesin family member 7 1.12909
KIAA0586 KIAA0586 1.12066
NPHP1 nephronophthisis 1 (juvenile) 1.11183
TTC26 tetratricopeptide repeat domain 26 1.10175
C7ORF13 chromosome 7 open reading frame 13 1.10175
TBC1D32 TBC1 domain family, member 32 1.10175
DHCR7 7-dehydrocholesterol reductase 1.10048
MSX1 msh homeobox 1 1.08957
HOXA13 homeobox A13 1.0837
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.07782
IFT52 intraflagellar transport 52 1.04588
NOM1 nucleolar protein with MIF4G domain 1 1.04335
BBS9 Bardet-Biedl syndrome 9 1.03872
CEP70 centrosomal protein 70kDa 1.02988
TTC21B tetratricopeptide repeat domain 21B 1.01807
WDR34 WD repeat domain 34 1.01638
UBTD2 ubiquitin domain containing 2 1.00035
ETV5 ets variant 5 0.988957
MSX2 msh homeobox 2 0.977165
IFT46 intraflagellar transport 46 0.974642
EN2 engrailed homeobox 2 0.966244
FBXW4 F-box and WD repeat domain containing 4 0.960797
RPGRIP1L RPGRIP1-like 0.959123
TCTN2 tectonic family member 2 0.951604
TCTN1 tectonic family member 1 0.950769
MNX1 motor neuron and pancreas homeobox 1 0.937044
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 0.906909
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 0.905675
IFT88 intraflagellar transport 88 0.888438
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0.886799
PTER phosphotriesterase related 0.882292
TRIM32 tripartite motif containing 32 0.875738
KLF10 Kruppel-like factor 10 0.874919
PLLP plasmolipin 0.873691
CCDC122 coiled-coil domain containing 122 0.872872
WNT8B wingless-type MMTV integration site family, member 8B 0.870415
TBX3 T-box 3 0.870006
SDCCAG8 serologically defined colon cancer antigen 8 0.858952
BRD4 bromodomain containing 4 0.850354
MECOM MDS1 and EVI1 complex locus 0.842982
EBP emopamil binding protein (sterol isomerase) 0.834378
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 0.833558
WDR60 WD repeat domain 60 0.827409
FBXW11 F-box and WD repeat domain containing 11 0.808129
ZIC3 Zic family member 3 0.797052
HOXB8 homeobox B8 0.792131
SOX9 SRY (sex determining region Y)-box 9 0.774523
SCLT1 sodium channel and clathrin linker 1 0.774523
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.769618
MIPOL1 mirror-image polydactyly 1 0.76921
COX20 COX20 cytochrome c oxidase assembly factor 0.768801
PARD6B par-6 family cell polarity regulator beta 0.762271
GREM1 gremlin 1, DAN family BMP antagonist 0.759416
SALL4 spalt-like transcription factor 4 0.748017
GPC5 glypican 5 0.74436
TWIST1 twist family bHLH transcription factor 1 0.741923
EIF3C eukaryotic translation initiation factor 3, subunit C 0.736243
IFT172 intraflagellar transport 172 0.736243
GPC3 glypican 3 0.733406
RAB23 RAB23, member RAS oncogene family 0.72329
TSC22D1 TSC22 domain family, member 1 0.72329
TULP3 tubby like protein 3 0.710378
HOXD10 homeobox D10 0.707961
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.706351
DISP1 dispatched homolog 1 (Drosophila) 0.69751
HYLS1 hydrolethalus syndrome 1 0.696306
IFT140 intraflagellar transport 140 0.689492
NPHP3 nephronophthisis 3 (adolescent) 0.684292
ZNF141 zinc finger protein 141 0.683493
EMX2 empty spiracles homeobox 2 0.681894
DPH5 diphthamide biosynthesis 5 0.681894
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.680297
APOPT1 apoptogenic 1, mitochondrial 0.668742
EXOC7 exocyst complex component 7 0.667947
SMO smoothened, frizzled class receptor 0.667152
KIF3A kinesin family member 3A 0.662784
SOX6 SRY (sex determining region Y)-box 6 0.659215
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.651298
RANBP17 RAN binding protein 17 0.650508
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.646953
WNT7B wingless-type MMTV integration site family, member 7B 0.646165
MYO9A myosin IXA 0.633563
DPH2 DPH2 homolog (S. cerevisiae) 0.633563
BARX1 BARX homeobox 1 0.631205
CNTLN centlein, centrosomal protein 0.619051
PTCH2 patched 2 0.614356
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.613965
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.609666
ARHGAP6 Rho GTPase activating protein 6 0.609276
KIFC3 kinesin family member C3 0.605762
TBX2 T-box 2 0.59874
NBAS neuroblastoma amplified sequence 0.597571
SIX6 SIX homeobox 6 0.590948
GDF5 growth differentiation factor 5 0.590948
CTC1 CTS telomere maintenance complex component 1 0.588612
GPC4 glypican 4 0.585108
EPHA7 EPH receptor A7 0.578494
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 0.570718
ZIC2 Zic family member 2 0.567997
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.567609
DLG3 discs, large homolog 3 (Drosophila) 0.563723
ETV4 ets variant 4 0.563335
NHEJ1 nonhomologous end-joining factor 1 0.561392
INTU inturned planar cell polarity protein 0.560227
GPC6 glypican 6 0.559062
LPAR6 lysophosphatidic acid receptor 6 0.554791
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.546256
SUFU suppressor of fused homolog (Drosophila) 0.541992
PRICKLE2 prickle homolog 2 (Drosophila) 0.534635
FKBP8 FK506 binding protein 8, 38kDa 0.532314
NOTCH1 notch 1 0.524202
INVS inversin 0.52343
COG6 component of oligomeric golgi complex 6 0.52343
GMFB glia maturation factor, beta 0.522659
SOSTDC1 sclerostin domain containing 1 0.516879
FOXM1 forkhead box M1 0.510344
EN1 engrailed homeobox 1 0.509192
FBXO8 F-box protein 8 0.502292
CFC1 cripto, FRL-1, cryptic family 1 0.494648
DIAPH3 diaphanous-related formin 3 0.494648
EHD1 EH-domain containing 1 0.494266
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.482084
EFNB1 ephrin-B1 0.470711
FGF19 fibroblast growth factor 19 0.469576
HOXB6 homeobox B6 0.46466
DPH1 diphthamide biosynthesis 1 0.461261
GRIP1 glutamate receptor interacting protein 1 0.460129
FGF1 fibroblast growth factor 1 (acidic) 0.460129
TBX5 T-box 5 0.460129
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.457487
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.457109
ARL3 ADP-ribosylation factor-like 3 0.443171
ELSPBP1 epididymal sperm binding protein 1 0.43941
NOG noggin 0.435275
SIX3 SIX homeobox 3 0.433772
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.429642
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.427765
NODAL nodal growth differentiation factor 0.420266
CCDC62 coiled-coil domain containing 62 0.412405
PAX1 paired box 1 0.412031
WNT16 wingless-type MMTV integration site family, member 16 0.408666
FGF10 fibroblast growth factor 10 0.397098
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.394491
LCA5 Leber congenital amaurosis 5 0.375179
HCCS holocytochrome c synthase 0.374438
CENPC centromere protein C 0.373328
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.361133
PITX1 paired-like homeodomain 1 0.360026
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.355972
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.353763
ZBTB16 zinc finger and BTB domain containing 16 0.346777
FRAS1 Fraser extracellular matrix complex subunit 1 0.346042
BRWD1 bromodomain and WD repeat domain containing 1 0.342006
ACD adrenocortical dysplasia homolog (mouse) 0.336144
DPP6 dipeptidyl-peptidase 6 0.32993
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.328834
FGFR2 fibroblast growth factor receptor 2 0.32373
MCHR1 melanin-concentrating hormone receptor 1 0.321545
SOX5 SRY (sex determining region Y)-box 5 0.315366
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.311377
ZFPM2 zinc finger protein, FOG family member 2 0.307395
CENPE centromere protein E, 312kDa 0.304503
MYO7A myosin VIIA 0.299092
RBP2 retinol binding protein 2, cellular 0.298011
DMRT1 doublesex and mab-3 related transcription factor 1 0.284728
CCM2 cerebral cavernous malformation 2 0.279724
AFP alpha-fetoprotein 0.275089
IGF2 insulin-like growth factor 2 0.254183
SPRED1 sprouty-related, EVH1 domain containing 1 0.250663
BMP2 bone morphogenetic protein 2 0.244696
RUNX2 runt-related transcription factor 2 0.242945
PPL periplakin 0.241895
CKAP2 cytoskeleton associated protein 2 0.238403
COL9A2 collagen, type IX, alpha 2 0.237706
ALDOB aldolase B, fructose-bisphosphate 0.237706
ADD2 adducin 2 (beta) 0.236312
ARX aristaless related homeobox 0.234225
NEO1 neogenin 1 0.230755
TRPS1 trichorhinophalangeal syndrome I 0.230409
TLX3 T-cell leukemia homeobox 3 0.222136
WNT7A wingless-type MMTV integration site family, member 7A 0.209248
BMP7 bone morphogenetic protein 7 0.199033
FLOT1 flotillin 1 0.194865
HOXB7 homeobox B7 0.193915
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.187719
WNT10B wingless-type MMTV integration site family, member 10B 0.180937
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.178682
AGO2 argonaute RISC catalytic component 2 0.170054
EPHB3 EPH receptor B3 0.169812
PDGFC platelet derived growth factor C 0.16933
ZFPM1 zinc finger protein, FOG family member 1 0.168148
FOXD3 forkhead box D3 0.167915
PAX9 paired box 9 0.165217
PCDH15 protocadherin-related 15 0.165001
SAR1A secretion associated, Ras related GTPase 1A 0.164786
CRABP2 cellular retinoic acid binding protein 2 0.163938
RAP2B RAP2B, member of RAS oncogene family 0.162908
RASA3 RAS p21 protein activator 3 0.162109
FMN1 formin 1 0.161912
RAB1B RAB1B, member RAS oncogene family 0.160948
THEM4 thioesterase superfamily member 4 0.160574
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.160203
DRD1 dopamine receptor D1 0.159838