pneumonia Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. (Human Disease Ontology, DOID_552)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0002090
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Genes

53 genes associated with the pneumonia phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ADA adenosine deaminase
ALMS1 Alstrom syndrome protein 1
BLNK B-cell linker
BTK Bruton agammaglobulinemia tyrosine kinase
CARD11 caspase recruitment domain family, member 11
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC114 coiled-coil domain containing 114
CD79B CD79b molecule, immunoglobulin-associated beta
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
COL11A2 collagen, type XI, alpha 2
COL2A1 collagen, type II, alpha 1
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DCLRE1C DNA cross-link repair 1C
DDR2 discoidin domain receptor tyrosine kinase 2
DNAI1 dynein, axonemal, intermediate chain 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
FMO3 flavin containing monooxygenase 3
GBA glucosidase, beta, acid
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
ICOS inducible T-cell co-stimulator
IGHM immunoglobulin heavy constant mu
IGLL1 immunoglobulin lambda-like polypeptide 1
IL21R interleukin 21 receptor
IL2RG interleukin 2 receptor, gamma
JAK3 Janus kinase 3
KMT2D lysine (K)-specific methyltransferase 2D
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
NBN nibrin
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NIPBL Nipped-B homolog (Drosophila)
OFD1 oral-facial-digital syndrome 1
ORC6 origin recognition complex, subunit 6
PEPD peptidase D
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PNP purine nucleoside phosphorylase
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RANBP2 RAN binding protein 2
SFTPA2 surfactant protein A2
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
USB1 U6 snRNA biogenesis 1
WAS Wiskott-Aldrich syndrome
WDR19 WD repeat domain 19
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB24 zinc finger and BTB domain containing 24