pleural Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

194 genes co-occuring with the biological term pleural in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ACVR1 activin A receptor, type I
ADA adenosine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPT1 angiopoietin 1
APOE apolipoprotein E
AQP1 aquaporin 1 (Colton blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
AVEN apoptosis, caspase activation inhibitor
AXL AXL receptor tyrosine kinase
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BIRC5 baculoviral IAP repeat containing 5
BMP6 bone morphogenetic protein 6
BPIFA1 BPI fold containing family A, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
CA9 carbonic anhydrase IX
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CADM1 cell adhesion molecule 1
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL22 chemokine (C-C motif) ligand 22
CD247 CD247 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CLDN1 claudin 1
CLDN4 claudin 4
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL18A1 collagen, type XVIII, alpha 1
CRP C-reactive protein, pentraxin-related
CTSH cathepsin H
CTSS cathepsin S
CUL1 cullin 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DPP4 dipeptidyl-peptidase 4
DVL3 dishevelled segment polarity protein 3
EBAG9 estrogen receptor binding site associated, antigen, 9
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGFR epidermal growth factor receptor
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGFR1 fibroblast growth factor receptor 1
FHIT fragile histidine triad
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
GAS5 growth arrest-specific 5 (non-protein coding)
GDF10 growth differentiation factor 10
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSPA1A heat shock 70kDa protein 1A
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL10 interleukin 10
IL16 interleukin 16
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL6 interleukin 6
IL9 interleukin 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITLN1 intelectin 1 (galactofuranose binding)
JUP junction plakoglobin
KDR kinase insert domain receptor
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT19 keratin 19, type I
LDHA lactate dehydrogenase A
LGALS3 lectin, galactoside-binding, soluble, 3
LTB4R2 leukotriene B4 receptor 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIR126 microRNA 126
MIR145 microRNA 145
MIR16-1 microRNA 16-1
MIR16-2 microRNA 16-2
MIR198 microRNA 198
MIR21 microRNA 21
MIR23A microRNA 23a
MIR625 microRNA 625
MIR92A1 microRNA 92a-1
MKI67 marker of proliferation Ki-67
MMP10 matrix metallopeptidase 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MSLN mesothelin
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO18B myosin XVIIIB
NCAM1 neural cell adhesion molecule 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF2 neurofibromin 2 (merlin)
NKX2-1 NK2 homeobox 1
NLRP3 NLR family, pyrin domain containing 3
NPPB natriuretic peptide B
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTS neurotensin
PARP1 poly (ADP-ribose) polymerase 1
PAX8 paired box 8
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPN podoplanin
PDZK1IP1 PDZK1 interacting protein 1
PEA15 phosphoprotein enriched in astrocytes 15
PEPD peptidase D
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKM pyruvate kinase, muscle
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PLXNA1 plexin A1
POSTN periostin, osteoblast specific factor
PPARA peroxisome proliferator-activated receptor alpha
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVT1 Pvt1 oncogene (non-protein coding)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100A4 S100 calcium binding protein A4
SCGB2A2 secretoglobin, family 2A, member 2
SEPT9 septin 9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHOX2 short stature homeobox 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR4 somatostatin receptor 4
STAT1 signal transducer and activator of transcription 1, 91kDa
TACSTD2 tumor-associated calcium signal transducer 2
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
THY1 Thy-1 cell surface antigen
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TM4SF1 transmembrane 4 L six family member 1
TNF tumor necrosis factor
TP53 tumor protein p53
TP63 tumor protein p63
TRIP6 thyroid hormone receptor interactor 6
TUBB3 tubulin, beta 3 class III
TUSC2 tumor suppressor candidate 2
TWIST1 twist family bHLH transcription factor 1
TXNDC2 thioredoxin domain containing 2 (spermatozoa)
UPK3A uroplakin 3A
VEGFA vascular endothelial growth factor A
WFDC2 WAP four-disulfide core domain 2
WIF1 WNT inhibitory factor 1
WT1 Wilms tumor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1
ZEB1 zinc finger E-box binding homeobox 1
ZIC1 Zic family member 1