pleural empyema Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A soft tissue infectious disease that involves accumulation of pus in the pleural cavity as a result of infection within the lung (pneumonia) or a lung abscess spreading into the space. The symptoms include cough, fever, chest pain, sweating and shortness of breath. (Human Disease Ontology, DOID_3798)
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52 genes co-occuring with the disease pleural empyema in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PDLIM7 PDZ and LIM domain 7 (enigma) 1.55291
CTSC cathepsin C 1.40526
IGH immunoglobulin heavy locus 1.24385
PTBP3 polypyrimidine tract binding protein 3 1.20526
MAN1A1 mannosidase, alpha, class 1A, member 1 0.948269
ADA adenosine deaminase 0.815104
IFI27 interferon, alpha-inducible protein 27 0.765943
SCYL1 SCY1-like 1 (S. cerevisiae) 0.75005
HSF4 heat shock transcription factor 4 0.749237
ENO2 enolase 2 (gamma, neuronal) 0.735027
DPEP1 dipeptidase 1 (renal) 0.726929
SFTPD surfactant protein D 0.680697
TADA1 transcriptional adaptor 1 0.672722
CPSF3L cleavage and polyadenylation specific factor 3-like 0.617486
IRAK4 interleukin-1 receptor-associated kinase 4 0.603811
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.598351
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.588612
USF2 upstream transcription factor 2, c-fos interacting 0.564112
ATN1 atrophin 1 0.550522
CD79A CD79a molecule, immunoglobulin-associated alpha 0.533475
TREM1 triggering receptor expressed on myeloid cells 1 0.524974
FGR FGR proto-oncogene, Src family tyrosine kinase 0.516879
HES5 hes family bHLH transcription factor 5 0.483224
PLAT plasminogen activator, tissue 0.47753
CRP C-reactive protein, pentraxin-related 0.420266
VIL1 villin 1 0.407919
LYZ lysozyme 0.403811
CD7 CD7 molecule 0.397471
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.371477
ALB albumin 0.350084
AVPR2 arginine vasopressin receptor 2 0.333218
GPANK1 G patch domain and ankyrin repeats 1 0.322637
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.314278
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.299812
TP53 tumor protein p53 0.293334
WDFY2 WD repeat and FYVE domain containing 2 0.293334
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.274732
FSCN1 fascin actin-bundling protein 1 0.271886
SH2D1A SH2 domain containing 1A 0.253479
PAX5 paired box 5 0.237706
CD4 CD4 molecule 0.229716
EPCAM epithelial cell adhesion molecule 0.211934
IL10 interleukin 10 0.194232
HBD hemoglobin, delta 0.192344
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.178403
CD19 CD19 molecule 0.16933
TGFB1 transforming growth factor, beta 1 0.169091
CD24 CD24 molecule 0.169091
CD68 CD68 molecule 0.163729
NCAM1 neural cell adhesion molecule 1 0.162505
IFNG interferon, gamma 0.162505
POMC proopiomelanocortin 0.142251