platelet degranulation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. (Gene Ontology, GO_0002576)
External Link http://amigo.geneontology.org/amigo/term/GO:0002576
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Genes

79 genes participating in the platelet degranulation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACTN1 actinin, alpha 1
ACTN2 actinin, alpha 2
ACTN4 actinin, alpha 4
ALB albumin
ALDOA aldolase A, fructose-bisphosphate
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
BRPF3 bromodomain and PHD finger containing, 3
CALU calumenin
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CD36 CD36 molecule (thrombospondin receptor)
CD63 CD63 molecule
CD9 CD9 molecule
CFD complement factor D (adipsin)
CFL1 cofilin 1 (non-muscle)
CLU clusterin
EGF epidermal growth factor
F13A1 coagulation factor XIII, A1 polypeptide
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLNA filamin A, alpha
FN1 fibronectin 1
GAS6 growth arrest-specific 6
HABP4 hyaluronan binding protein 4
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HRG histidine-rich glycoprotein
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KNG1 kininogen 1
LAMP2 lysosomal-associated membrane protein 2
LEFTY2 left-right determination factor 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MMRN1 multimerin 1
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PF4 platelet factor 4
PFN1 profilin 1
PLEK pleckstrin
PLG plasminogen
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PROS1 protein S (alpha)
PSAP prosaposin
SCG3 secretogranin III
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SOD1 superoxide dismutase 1, soluble
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRGN serglycin
STXBP1 syntaxin binding protein 1
TF transferrin
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLN1 talin 1
TMSB4X thymosin beta 4, X-linked
TTN titin
TUBA4A tubulin, alpha 4a
VCL vinculin
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VWF von Willebrand factor
WDR1 WD repeat domain 1