placenta cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

340 genes co-occuring with the disease placenta cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CSH2 chorionic somatomammotropin hormone 2 2.2889
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 2.27427
LGALS1 lectin, galactoside-binding, soluble, 1 1.59028
AFP alpha-fetoprotein 1.57289
PSG9 pregnancy specific beta-1-glycoprotein 9 1.46583
STARD7 StAR-related lipid transfer (START) domain containing 7 1.35899
HLA-G major histocompatibility complex, class I, G 1.29571
ERV3-1 endogenous retrovirus group 3, member 1 1.2395
GCH1 GTP cyclohydrolase 1 1.21738
GH2 growth hormone 2 1.2031
ZNF184 zinc finger protein 184 1.0669
INHA inhibin, alpha 1.05387
ZNHIT2 zinc finger, HIT-type containing 2 1.04798
ALPPL2 alkaline phosphatase, placental-like 2 1.03704
ALPP alkaline phosphatase, placental 1.03156
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.01807
ALPL alkaline phosphatase, liver/bone/kidney 1.01343
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 1.01132
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.952021
CGB chorionic gonadotropin, beta polypeptide 0.934556
ENDOU endonuclease, polyU-specific 0.928346
CTSC cathepsin C 0.887618
FBXW8 F-box and WD repeat domain containing 8 0.881882
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.868368
CGA glycoprotein hormones, alpha polypeptide 0.865093
LNPEP leucyl/cystinyl aminopeptidase 0.858952
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.858543
GH1 growth hormone 1 0.857724
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.840934
NANOG Nanog homeobox 0.834788
CPM carboxypeptidase M 0.826589
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 0.823308
ERVW-1 endogenous retrovirus group W, member 1 0.815924
CGB8 chorionic gonadotropin, beta polypeptide 8 0.815924
DHFR dihydrofolate reductase 0.794591
PSG3 pregnancy specific beta-1-glycoprotein 3 0.774523
GPC3 glypican 3 0.761862
SOX17 SRY (sex determining region Y)-box 17 0.756971
F2R coagulation factor II (thrombin) receptor 0.754527
CUL7 cullin 7 0.746798
MCAM melanoma cell adhesion molecule 0.742735
LVRN laeverin 0.741111
SOX2 SRY (sex determining region Y)-box 2 0.739488
HOXB6 homeobox B6 0.734622
TEAD3 TEA domain family member 3 0.725311
GATAD1 GATA zinc finger domain containing 1 0.707961
GCM1 glial cells missing homolog 1 (Drosophila) 0.706754
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.695504
EBF4 early B-cell factor 4 0.691495
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 0.687091
TFPI2 tissue factor pathway inhibitor 2 0.684692
TP53 tumor protein p53 0.681894
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.680297
POU5F1 POU class 5 homeobox 1 0.680297
HSPE1 heat shock 10kDa protein 1 0.676706
DSCR4 Down syndrome critical region 4 0.663578
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.662784
TCL1A T-cell leukemia/lymphoma 1A 0.650903
HPSE heparanase 0.647743
PZP pregnancy-zone protein 0.640251
GNRHR2 gonadotropin-releasing hormone (type 2) receptor 2, pseudogene 0.63907
SNTG1 syntrophin, gamma 1 0.623359
SALL4 spalt-like transcription factor 4 0.623359
CTBS chitobiase, di-N-acetyl- 0.620226
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.619442
ASCL2 achaete-scute family bHLH transcription factor 2 0.614356
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.613965
PGF placental growth factor 0.61162
HOXC6 homeobox C6 0.609276
SYNE1 spectrin repeat containing, nuclear envelope 1 0.60303
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.60147
NCAPG non-SMC condensin I complex, subunit G 0.59952
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.598351
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 0.596012
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.578883
RASGEF1A RasGEF domain family, member 1A 0.575772
HLA-A major histocompatibility complex, class I, A 0.563723
PAEP progestagen-associated endometrial protein 0.561781
TGFB1 transforming growth factor, beta 1 0.561004
NFE2L3 nuclear factor, erythroid 2-like 3 0.559839
PTN pleiotrophin 0.557509
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.539667
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.53928
LEP leptin 0.537344
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.534248
HOXA11 homeobox A11 0.533088
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.533088
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.532701
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.528063
CSF1R colony stimulating factor 1 receptor 0.523816
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.52343
MED13 mediator complex subunit 13 0.522659
PRL prolactin 0.514956
AURKB aurora kinase B 0.511112
NCR2 natural cytotoxicity triggering receptor 2 0.509192
IGF2 insulin-like growth factor 2 0.504973
ANXA5 annexin A5 0.494266
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 0.490072
ERBB2 erb-b2 receptor tyrosine kinase 2 0.484744
LGALS7 lectin, galactoside-binding, soluble, 7 0.483224
UBA2 ubiquitin-like modifier activating enzyme 2 0.483224
SMAD3 SMAD family member 3 0.482464
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.478289
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 0.477151
NEK2 NIMA-related kinase 2 0.469576
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.466928
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.464283
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.463905
RRM2 ribonucleotide reductase M2 0.458996
GNRHR gonadotropin-releasing hormone receptor 0.457109
LHCGR luteinizing hormone/choriogonadotropin receptor 0.453339
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.448441
MUC15 mucin 15, cell surface associated 0.446935
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.443923
HOXB7 homeobox B7 0.442042
NCR3 natural cytotoxicity triggering receptor 3 0.439786
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.436402
TEAD4 TEA domain family member 4 0.436402
PPME1 protein phosphatase methylesterase 1 0.430017
GPER1 G protein-coupled estrogen receptor 1 0.42289
NEK8 NIMA-related kinase 8 0.421016
JUN jun proto-oncogene 0.419142
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.418768
KIF7 kinesin family member 7 0.415773
HMGA1 high mobility group AT-hook 1 0.413901
EFNA4 ephrin-A4 0.413527
CDX2 caudal type homeobox 2 0.411283
ZFYVE1 zinc finger, FYVE domain containing 1 0.408292
BOK BCL2-related ovarian killer 0.408292
POU5F1B POU class 5 homeobox 1B 0.401945
ESRRA estrogen-related receptor alpha 0.401199
GATA2 GATA binding protein 2 0.401199
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.398962
SPATA7 spermatogenesis associated 7 0.395235
LEPR leptin receptor 0.392629
SP1 Sp1 transcription factor 0.391885
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.387794
NMUR2 neuromedin U receptor 2 0.387423
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 0.386679
HLA-C major histocompatibility complex, class I, C 0.382594
PTPRS protein tyrosine phosphatase, receptor type, S 0.381481
PAPPA2 pappalysin 2 0.380739
PCTP phosphatidylcholine transfer protein 0.376661
DNASE1 deoxyribonuclease I 0.37592
UTF1 undifferentiated embryonic cell transcription factor 1 0.37592
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.374809
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.370737
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.369628
PCBP1 poly(rC) binding protein 1 0.368888
MNX1 motor neuron and pancreas homeobox 1 0.36741
KRT7 keratin 7, type II 0.366301
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.365193
ERBB4 erb-b2 receptor tyrosine kinase 4 0.359289
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 0.358551
CDC123 cell division cycle 123 0.356341
TF transferrin 0.351923
KRT18 keratin 18, type I 0.348246
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.345675
FN1 fibronectin 1 0.344207
MCM7 minichromosome maintenance complex component 7 0.343473
TIMP3 TIMP metallopeptidase inhibitor 3 0.341639
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.33944
ERH enhancer of rudimentary homolog (Drosophila) 0.332121
FOXF2 forkhead box F2 0.328105
LAP3 leucine aminopeptidase 3 0.322637
FURIN furin (paired basic amino acid cleaving enzyme) 0.322637
CTSZ cathepsin Z 0.321909
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.321181
PCNA proliferating cell nuclear antigen 0.318999
HAUS3 HAUS augmin-like complex, subunit 3 0.317545
IL1B interleukin 1, beta 0.317182
CNOT2 CCR4-NOT transcription complex, subunit 2 0.316092
PDLIM5 PDZ and LIM domain 5 0.312827
GDF3 growth differentiation factor 3 0.310652
HMP19 HMP19 protein 0.31029
EGFR epidermal growth factor receptor 0.305226
AKR1C3 aldo-keto reductase family 1, member C3 0.304503
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.303059
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.296571
THRA thyroid hormone receptor, alpha 0.286877
TGFB3 transforming growth factor, beta 3 0.284728
IK IK cytokine, down-regulator of HLA II 0.284013
ERBB3 erb-b2 receptor tyrosine kinase 3 0.283655
PLIN2 perilipin 2 0.281153
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.280796
SIGMAR1 sigma non-opioid intracellular receptor 1 0.280439
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.279724
CDKN2A cyclin-dependent kinase inhibitor 2A 0.279367
DLX4 distal-less homeobox 4 0.279367
PTTG1 pituitary tumor-transforming 1 0.27794
B2M beta-2-microglobulin 0.277227
NID1 nidogen 1 0.277227
RNF31 ring finger protein 31 0.27687
CSHL1 chorionic somatomammotropin hormone-like 1 0.275445
WASH7P WAS protein family homolog 7 pseudogene 0.271886
NCR1 natural cytotoxicity triggering receptor 1 0.269043
WASH1 WAS protein family homolog 1 0.268332
LDHC lactate dehydrogenase C 0.265849
WASH6P WAS protein family homolog 6 pseudogene 0.265849
ESR1 estrogen receptor 1 0.264431
SDC3 syndecan 3 0.263014
GPR162 G protein-coupled receptor 162 0.262306
RXRA retinoid X receptor, alpha 0.261599
LAMA2 laminin, alpha 2 0.259477
TAGLN2 transgelin 2 0.257711
MME membrane metallo-endopeptidase 0.256652
ACOT1 acyl-CoA thioesterase 1 0.255946
MCM4 minichromosome maintenance complex component 4 0.252774
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.251366
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.246448
ASMT acetylserotonin O-methyltransferase 0.238752
SYN2 synapsin II 0.238752
DCN decorin 0.238403
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.238054
STS steroid sulfatase (microsomal), isozyme S 0.237009
ESRRB estrogen-related receptor beta 0.23666
GJA5 gap junction protein, alpha 5, 40kDa 0.236312
GALP galanin-like peptide 0.235964
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.232489
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.232142
TIMP1 TIMP metallopeptidase inhibitor 1 0.22937
DIO3 deiodinase, iodothyronine, type III 0.22937
CAPN1 calpain 1, (mu/I) large subunit 0.22937
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.228333
CALR calreticulin 0.225229
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.222479
CGB7 chorionic gonadotropin, beta polypeptide 7 0.220766
CGB5 chorionic gonadotropin, beta polypeptide 5 0.219398
ASCL3 achaete-scute family bHLH transcription factor 3 0.218034
DNTT DNA nucleotidylexotransferase 0.217012
PI3 peptidase inhibitor 3, skin-derived 0.213959
S100P S100 calcium binding protein P 0.212945
MCM6 minichromosome maintenance complex component 6 0.212271
PDGFB platelet-derived growth factor beta polypeptide 0.210253
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 0.207578
HAPLN1 hyaluronan and proteoglycan link protein 1 0.20658
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.201962
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.199356
FLT1 fms-related tyrosine kinase 1 0.199356
DIO1 deiodinase, iodothyronine, type I 0.198064
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.19742
CENPV centromere protein V 0.195183
TMEM245 transmembrane protein 245 0.1936
PARD6A par-6 family cell polarity regulator alpha 0.193285
FGF4 fibroblast growth factor 4 0.188938
HRAS Harvey rat sarcoma viral oncogene homolog 0.188326
PEX1 peroxisomal biogenesis factor 1 0.188326
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.187719
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 0.187113
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.18591
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.185016
JAK2 Janus kinase 2 0.184424
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.183248
DUSP5 dual specificity phosphatase 5 0.182957
OSM oncostatin M 0.182666
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.180652
AANAT aralkylamine N-acetyltransferase 0.180084
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.178403
CLIC1 chloride intracellular channel 1 0.174617
ACTG1 actin gamma 1 0.169571
GPC1 glypican 1 0.167682
PNMA2 paraneoplastic Ma antigen 2 0.167224
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.166995
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.166544
MMP2 matrix metallopeptidase 2 0.165874
RAET1E retinoic acid early transcript 1E 0.165874
SYN3 synapsin III 0.165655
DNM1 dynamin 1 0.162707
HES4 hes family bHLH transcription factor 4 0.160948
TNF tumor necrosis factor 0.160761
RPS6 ribosomal protein S6 0.160021
DNAH8 dynein, axonemal, heavy chain 8 0.159658
TFRC transferrin receptor 0.158434
FUT2 fucosyltransferase 2 (secretor status included) 0.158434
HOPX HOP homeobox 0.158266
SRY sex determining region Y 0.144647
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.141637
PCSK6 proprotein convertase subtilisin/kexin type 6 0.141621
CUTA cutA divalent cation tolerance homolog (E. coli) 0.14141
RGN regucalcin 0.140904
HES2 hes family bHLH transcription factor 2 0.14071
PCSK7 proprotein convertase subtilisin/kexin type 7 0.139905
PAOX polyamine oxidase (exo-N4-amino) 0.139865
ACSL6 acyl-CoA synthetase long-chain family member 6 0.139804
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.139678
ERAP1 endoplasmic reticulum aminopeptidase 1 0.139506
NFE2 nuclear factor, erythroid 2 0.139506
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.137607
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.13723
PLIN1 perilipin 1 0.137184
ACSL5 acyl-CoA synthetase long-chain family member 5 0.136569
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.136234
ACTB actin, beta 0.135231
WNT5A wingless-type MMTV integration site family, member 5A 0.134444
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.133636
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.13358
FGF19 fibroblast growth factor 19 0.133256
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.131829
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.13085
LDHA lactate dehydrogenase A 0.130575
ACSL4 acyl-CoA synthetase long-chain family member 4 0.130193
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.128766
ENO2 enolase 2 (gamma, neuronal) 0.128123
PTER phosphotriesterase related 0.128071
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.125703
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.125465
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.124408
MUC3A mucin 3A, cell surface associated 0.124375
SOX3 SRY (sex determining region Y)-box 3 0.122455
FOXD3 forkhead box D3 0.120477
ZNF185 zinc finger protein 185 (LIM domain) 0.119919
MEGF6 multiple EGF-like-domains 6 0.119786
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.119477
HHAT hedgehog acyltransferase 0.119003
RPSA ribosomal protein SA 0.117886
CD200 CD200 molecule 0.117643
FASLG Fas ligand (TNF superfamily, member 6) 0.115261
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.115127
HAS2 hyaluronan synthase 2 0.11486
FOSL1 FOS-like antigen 1 0.114453
JUND jun D proto-oncogene 0.111612
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.111521
MUC4 mucin 4, cell surface associated 0.105953
PARK7 parkinson protein 7 0.104744
CCNA2 cyclin A2 0.103426
F10 coagulation factor X 0.103388
EZR ezrin 0.102566
CCNE1 cyclin E1 0.101917
HBEGF heparin-binding EGF-like growth factor 0.101649
INHBA inhibin, beta A 0.098969
SDC2 syndecan 2 0.098153
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.097702
GIF gastric intrinsic factor (vitamin B synthesis) 0.097204
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.096535
PGR progesterone receptor 0.096029
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.093395
PPARG peroxisome proliferator-activated receptor gamma 0.092951
AHR aryl hydrocarbon receptor 0.091973
ODC1 ornithine decarboxylase 1 0.090617
MMP10 matrix metallopeptidase 10 0.089698