pituitary cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An endocrine gland cancer located_in the pituitary gland located at the base of the brain. (Human Disease Ontology, DOID_1785)
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Genes

76 genes co-occuring with the disease pituitary cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
POMC proopiomelanocortin 2.57109
AIP aryl hydrocarbon receptor interacting protein 1.87837
CRH corticotropin releasing hormone 1.47989
PRL prolactin 1.47594
SST somatostatin 1.35594
GHRH growth hormone releasing hormone 1.00837
TRH thyrotropin-releasing hormone 1.00246
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 0.948269
MEN1 multiple endocrine neoplasia I 0.947019
IGF1 insulin-like growth factor 1 (somatomedin C) 0.924626
GNAS GNAS complex locus 0.921323
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.904442
SSTR5 somatostatin receptor 5 0.865093
S100G S100 calcium binding protein G 0.765127
SSTR2 somatostatin receptor 2 0.752898
ARG2 arginase 2 0.71925
RERG RAS-like, estrogen-regulated, growth inhibitor 0.713198
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.67551
RAB18 RAB18, member RAS oncogene family 0.655254
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.642615
DRD2 dopamine receptor D2 0.606543
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.583941
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.581996
TLE4 transducin-like enhancer of split 4 0.579272
TP53 tumor protein p53 0.577716
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.537344
PGK1 phosphoglycerate kinase 1 0.524588
SSTR1 somatostatin receptor 1 0.51188
MTO1 mitochondrial tRNA translation optimization 1 0.509959
PTTG1 pituitary tumor-transforming 1 0.497703
MSH5 mutS homolog 5 0.443547
GUK1 guanylate kinase 1 0.434524
TSC22D3 TSC22 domain family, member 3 0.42814
MKI67 marker of proliferation Ki-67 0.42139
MGMT O-6-methylguanine-DNA methyltransferase 0.379256
POU1F1 POU class 1 homeobox 1 0.377402
INS insulin 0.373328
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.355235
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.346042
SSTR4 somatostatin receptor 4 0.308842
FDX1 ferredoxin 1 0.308118
CRABP1 cellular retinoic acid binding protein 1 0.304864
F10 coagulation factor X 0.299092
MAP9 microtubule-associated protein 9 0.278654
CALB1 calbindin 1, 28kDa 0.269753
SSTR3 somatostatin receptor 3 0.253479
PCNA proliferating cell nuclear antigen 0.252422
MRI1 methylthioribose-1-phosphate isomerase 1 0.238752
HPN hepsin 0.22454
TXNRD2 thioredoxin reductase 2 0.222479
SNAP23 synaptosomal-associated protein, 23kDa 0.21974
MED12 mediator complex subunit 12 0.218715
IMMT inner membrane protein, mitochondrial 0.204263
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.198064
NSF N-ethylmaleimide-sensitive factor 0.194548
PDYN prodynorphin 0.188938
CHGA chromogranin A 0.181798
AVP arginine vasopressin 0.167915
ADCY2 adenylate cyclase 2 (brain) 0.153944
ASCL1 achaete-scute family bHLH transcription factor 1 0.140212
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.138896
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.13887
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.138852
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.138716
IFNA21 interferon, alpha 21 0.13866
IFNA17 interferon, alpha 17 0.1381
NGF nerve growth factor (beta polypeptide) 0.137618
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.136506
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.135262
EPCAM epithelial cell adhesion molecule 0.134602
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.13373
SYP synaptophysin 0.133148
MSH6 mutS homolog 6 0.133074
PDE4A phosphodiesterase 4A, cAMP-specific 0.132824
CALCA calcitonin-related polypeptide alpha 0.131673
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.131251