piromidic acid-4398 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the piromidic acid-4398 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADAM12 ADAM metallopeptidase domain 12
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADGRG2 adhesion G protein-coupled receptor G2
AEBP1 AE binding protein 1
ALDOB aldolase B, fructose-bisphosphate
ALPPL2 alkaline phosphatase, placental-like 2
APAF1 apoptotic peptidase activating factor 1
ARMCX4 armadillo repeat containing, X-linked 4
ASIC1 acid sensing (proton gated) ion channel 1
ATF7IP activating transcription factor 7 interacting protein
BCAM basal cell adhesion molecule (Lutheran blood group)
BGN biglycan
C10ORF10 chromosome 10 open reading frame 10
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCL17 chemokine (C-C motif) ligand 17
CCRL2 chemokine (C-C motif) receptor-like 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRMP1 collapsin response mediator protein 1
CXCL6 chemokine (C-X-C motif) ligand 6
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DCN decorin
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DIO2 deiodinase, iodothyronine, type II
DOCK10 dedicator of cytokinesis 10
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ERC1 ELKS/RAB6-interacting/CAST family member 1
FER1L4 fer-1-like family member 4, pseudogene (functional)
FPR2 formyl peptide receptor 2
FRMD1 FERM domain containing 1
FST follistatin
FYB FYN binding protein
GIMAP6 GTPase, IMAP family member 6
GJA4 gap junction protein, alpha 4, 37kDa
GM2A GM2 ganglioside activator
GPR39 G protein-coupled receptor 39
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSDMD gasdermin D
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXA9 homeobox A9
IFNA14 interferon, alpha 14
IL1B interleukin 1, beta
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRF5 interferon regulatory factor 5
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAG1 jagged 1
JAM3 junctional adhesion molecule 3
KANK1 KN motif and ankyrin repeat domains 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLHL35 kelch-like family member 35
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYZL6 lysozyme-like 6
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MYOZ1 myozenin 1
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NOTCH3 notch 3
NPAS3 neuronal PAS domain protein 3
PAX8 paired box 8
PIP prolactin-induced protein
POFUT1 protein O-fucosyltransferase 1
PRB3 proline-rich protein BstNI subfamily 3
PRDM12 PR domain containing 12
PRELP proline/arginine-rich end leucine-rich repeat protein
PTRF polymerase I and transcript release factor
RAB11B RAB11B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RARA retinoic acid receptor, alpha
RGS12 regulator of G-protein signaling 12
RUNX1 runt-related transcription factor 1
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A16 solute carrier family 6, member 16
SNTG1 syntrophin, gamma 1
SNX13 sorting nexin 13
SP110 SP110 nuclear body protein
SPPL2B signal peptide peptidase like 2B
SSX1 synovial sarcoma, X breakpoint 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TFEB transcription factor EB
TPPP3 tubulin polymerization-promoting protein family member 3
TRIM49 tripartite motif containing 49
TUBA3C tubulin, alpha 3c
VPRBP Vpr (HIV-1) binding protein
WNT16 wingless-type MMTV integration site family, member 16
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD3 abhydrolase domain containing 3
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY6 adenylate cyclase 6
AFAP1 actin filament associated protein 1
AHNAK2 AHNAK nucleoprotein 2
ALPK1 alpha-kinase 1
ANKRD36 ankyrin repeat domain 36
ANP32A-IT1 ANP32A intronic transcript 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
APOLD1 apolipoprotein L domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
AZI2 5-azacytidine induced 2
BAHCC1 BAH domain and coiled-coil containing 1
BAX BCL2-associated X protein
BCL9 B-cell CLL/lymphoma 9
C21ORF91 chromosome 21 open reading frame 91
C7ORF43 chromosome 7 open reading frame 43
CAMK1 calcium/calmodulin-dependent protein kinase I
CCP110 centriolar coiled coil protein 110kDa
CEP97 centrosomal protein 97kDa
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPY19L1P1 DPY19L1 pseudogene 1
EGFL7 EGF-like-domain, multiple 7
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETAA1 Ewing tumor-associated antigen 1
FBXO46 F-box protein 46
FBXO5 F-box protein 5
FGF13 fibroblast growth factor 13
FKRP fukutin related protein
GATA4 GATA binding protein 4
GLS2 glutaminase 2 (liver, mitochondrial)
GPR143 G protein-coupled receptor 143
GPR157 G protein-coupled receptor 157
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL15RA interleukin 15 receptor, alpha
INO80D INO80 complex subunit D
IRF9 interferon regulatory factor 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KRT86 keratin 86, type II
LRRC37A3 leucine rich repeat containing 37, member A3
MAGEF1 melanoma antigen family F1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MED23 mediator complex subunit 23
MUM1 melanoma associated antigen (mutated) 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOL12 nucleolar protein 12
PFDN6 prefoldin subunit 6
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A9 S100 calcium binding protein A9
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SNTA1 syntrophin, alpha 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SREK1IP1 SREK1-interacting protein 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TICAM1 toll-like receptor adaptor molecule 1
TMEM183A transmembrane protein 183A
TMOD3 tropomodulin 3 (ubiquitous)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM21 tripartite motif containing 21
TSGA10 testis specific, 10
TSPAN15 tetraspanin 15
UNKL unkempt family zinc finger-like
VLDLR very low density lipoprotein receptor
VWA1 von Willebrand factor A domain containing 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF286A zinc finger protein 286A
ZNF492 zinc finger protein 492
ZNF516 zinc finger protein 516
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652