piromidic acid-2996 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the piromidic acid-2996 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADRB1 adrenoceptor beta 1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C8ORF4 chromosome 8 open reading frame 4
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD24 CD24 molecule
CD300C CD300c molecule
CDO1 cysteine dioxygenase type 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DCN decorin
DGCR8 DGCR8 microprocessor complex subunit
DLX2 distal-less homeobox 2
DOC2B double C2-like domains, beta
DSCR4 Down syndrome critical region 4
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EN1 engrailed homeobox 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHB2 EPH receptor B2
EXO5 exonuclease 5
FAM65B family with sequence similarity 65, member B
FDPS farnesyl diphosphate synthase
FJX1 four jointed box 1 (Drosophila)
FOXA2 forkhead box A2
HFE hemochromatosis
HIST1H2BL histone cluster 1, H2bl
HOXA4 homeobox A4
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KEL Kell blood group, metallo-endopeptidase
KLK5 kallikrein-related peptidase 5
KRTAP2-4 keratin associated protein 2-4
LHFPL2 lipoma HMGIC fusion partner-like 2
LIMD2 LIM domain containing 2
LPAR1 lysophosphatidic acid receptor 1
LRP2 low density lipoprotein receptor-related protein 2
MAG myelin associated glycoprotein
MAP2K7 mitogen-activated protein kinase kinase 7
MARC1 mitochondrial amidoxime reducing component 1
MAU2 MAU2 sister chromatid cohesion factor
MCF2L MCF.2 cell line derived transforming sequence-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MVP major vault protein
MYOG myogenin (myogenic factor 4)
NF2 neurofibromin 2 (merlin)
NOS1 nitric oxide synthase 1 (neuronal)
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLFM1 olfactomedin 1
OPRM1 opioid receptor, mu 1
PCDHGA8 protocadherin gamma subfamily A, 8
PCGF2 polycomb group ring finger 2
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
RASAL1 RAS protein activator like 1 (GAP1 like)
RASAL2 RAS protein activator like 2
REPS2 RALBP1 associated Eps domain containing 2
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RPL23AP53 ribosomal protein L23a pseudogene 53
RUSC2 RUN and SH3 domain containing 2
SCG2 secretogranin II
SEMG2 semenogelin II
SHOX2 short stature homeobox 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC39A9 solute carrier family 39, member 9
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLMO1 slowmo homolog 1 (Drosophila)
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SORBS2 sorbin and SH3 domain containing 2
SPINK1 serine peptidase inhibitor, Kazal type 1
TAAR2 trace amine associated receptor 2
TAT tyrosine aminotransferase
TBX5 T-box 5
TFF2 trefoil factor 2
TMEM144 transmembrane protein 144
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNPO2 transportin 2
TRIL TLR4 interactor with leucine-rich repeats
TRPS1 trichorhinophalangeal syndrome I
UGT8 UDP glycosyltransferase 8
UNC119 unc-119 homolog (C. elegans)
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
WDR78 WD repeat domain 78
ZBTB20 zinc finger and BTB domain containing 20
ZNF280B zinc finger protein 280B
ZNF34 zinc finger protein 34
ZNF442 zinc finger protein 442
ZNF613 zinc finger protein 613
ZNF639 zinc finger protein 639
ZNF768 zinc finger protein 768
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADGRE5 adhesion G protein-coupled receptor E5
ADORA3 adenosine A3 receptor
AKTIP AKT interacting protein
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOC4 apolipoprotein C-IV
APOL6 apolipoprotein L, 6
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL15 ADP-ribosylation factor-like 15
BCAR3 breast cancer anti-estrogen resistance 3
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C3ORF18 chromosome 3 open reading frame 18
C8A complement component 8, alpha polypeptide
CASP5 caspase 5, apoptosis-related cysteine peptidase
CD79B CD79b molecule, immunoglobulin-associated beta
CD9 CD9 molecule
CLDN3 claudin 3
CLGN calmegin
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRIP1 cysteine-rich protein 1 (intestinal)
CTAGE9 CTAGE family, member 9
CTSD cathepsin D
DEXI Dexi homolog (mouse)
DNAL4 dynein, axonemal, light chain 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM13C family with sequence similarity 13, member C
FAM204A family with sequence similarity 204, member A
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCH1 GTP cyclohydrolase 1
GPR27 G protein-coupled receptor 27
HAMP hepcidin antimicrobial peptide
HIST1H2AI histone cluster 1, H2ai
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA6 homeobox A6
HOXB9 homeobox B9
HOXC8 homeobox C8
HRAS Harvey rat sarcoma viral oncogene homolog
ICAM2 intercellular adhesion molecule 2
IFT140 intraflagellar transport 140
IL12B interleukin 12B
IL18 interleukin 18
KIAA1456 KIAA1456
KPTN kaptin (actin binding protein)
KRT12 keratin 12, type I
KRT20 keratin 20, type I
LATS1 large tumor suppressor kinase 1
LIME1 Lck interacting transmembrane adaptor 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MOCS3 molybdenum cofactor synthesis 3
MRAS muscle RAS oncogene homolog
NME8 NME/NM23 family member 8
NMUR1 neuromedin U receptor 1
NSUN6 NOP2/Sun domain family, member 6
NTSR1 neurotensin receptor 1 (high affinity)
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PBOV1 prostate and breast cancer overexpressed 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGM3 phosphoglucomutase 3
PGP phosphoglycolate phosphatase
PIPOX pipecolic acid oxidase
PKD2L2 polycystic kidney disease 2-like 2
PLA2G15 phospholipase A2, group XV
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB3 proline-rich protein BstNI subfamily 3
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
REEP4 receptor accessory protein 4
RHOBTB2 Rho-related BTB domain containing 2
RPL23AP32 ribosomal protein L23a pseudogene 32
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIL1 SIL1 nucleotide exchange factor
SLC16A6 solute carrier family 16, member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX12 SRY (sex determining region Y)-box 12
SPINT1 serine peptidase inhibitor, Kunitz type 1
STAG3 stromal antigen 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM212 transmembrane protein 212
TRABD TraB domain containing
TRAIP TRAF interacting protein
TSPYL2 TSPY-like 2
UBL4A ubiquitin-like 4A
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZFYVE16 zinc finger, FYVE domain containing 16
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF16 zinc finger protein 16
ZNF177 zinc finger protein 177
ZNF415 zinc finger protein 415
ZNF574 zinc finger protein 574
ZNF665 zinc finger protein 665
ZNF81 zinc finger protein 81