pirinixic acid Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An aryl sulfide that has formula C14H14ClN3O2S. (Chemical Entities of Biological Interest Ontology, CHEBI_32509)
External Link http://ctdbase.org/detail.go?type=chem&acc=C006253
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Genes

180 genes/proteins interacting with the chemical pirinixic acid from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACAA1 acetyl-CoA acyltransferase 1
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACAT1 acetyl-CoA acetyltransferase 1
ACOT1 acyl-CoA thioesterase 1
ACOT2 acyl-CoA thioesterase 2
ACOT4 acyl-CoA thioesterase 4
ACOX1 acyl-CoA oxidase 1, palmitoyl
ADIPOQ adiponectin, C1Q and collagen domain containing
AGTR2 angiotensin II receptor, type 2
AHCY adenosylhomocysteinase
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDOB aldolase B, fructose-bisphosphate
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ARG1 arginase 1
ASGR1 asialoglycoprotein receptor 1
ASS1 argininosuccinate synthase 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BAG1 BCL2-associated athanogene
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
C3 complement component 3
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCNB1 cyclin B1
CCND1 cyclin D1
CCND3 cyclin D3
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CD36 CD36 molecule (thrombospondin receptor)
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CGB chorionic gonadotropin, beta polypeptide
CIDEA cell death-inducing DFFA-like effector a
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREBBP CREB binding protein
CROT carnitine O-octanoyltransferase
CSAD cysteine sulfinic acid decarboxylase
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL2 chemokine (C-X-C motif) ligand 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPP4 dipeptidyl-peptidase 4
ECH1 enoyl CoA hydratase 1, peroxisomal
EGFR epidermal growth factor receptor
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF4B eukaryotic translation initiation factor 4B
ELANE elastase, neutrophil expressed
ELOVL1 ELOVL fatty acid elongase 1
ELOVL5 ELOVL fatty acid elongase 5
ELOVL6 ELOVL fatty acid elongase 6
EP300 E1A binding protein p300
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
FBP1 fructose-1,6-bisphosphatase 1
FDPS farnesyl diphosphate synthase
FLG filaggrin
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FTCD formimidoyltransferase cyclodeaminase
GADD45B growth arrest and DNA-damage-inducible, beta
GJB1 gap junction protein, beta 1, 32kDa
GJB2 gap junction protein, beta 2, 26kDa
GNMT glycine N-methyltransferase
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPX1 glutathione peroxidase 1
GSR glutathione reductase
GSTA4 glutathione S-transferase alpha 4
GSTP1 glutathione S-transferase pi 1
HACL1 2-hydroxyacyl-CoA lyase 1
HADH hydroxyacyl-CoA dehydrogenase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HPX hemopexin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPH1 heat shock 105kDa/110kDa protein 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGFBP1 insulin-like growth factor binding protein 1
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
IVL involucrin
JUN jun proto-oncogene
KHK ketohexokinase (fructokinase)
LEP leptin
LOR loricrin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED1 mediator complex subunit 1
MLXIPL MLX interacting protein-like
MPO myeloperoxidase
MRPS6 mitochondrial ribosomal protein S6
MTTP microsomal triglyceride transfer protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCF1 neutrophil cytosolic factor 1
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOR1 nuclear receptor corepressor 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
ORM1 orosomucoid 1
ORM2 orosomucoid 2
OTC ornithine carbamoyltransferase
P4HB prolyl 4-hydroxylase, beta polypeptide
PCNA proliferating cell nuclear antigen
PCTP phosphatidylcholine transfer protein
PHEX phosphate regulating endopeptidase homolog, X-linked
PKLR pyruvate kinase, liver and RBC
PLIN2 perilipin 2
PPA1 pyrophosphatase (inorganic) 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRDX6 peroxiredoxin 6
PTGES2 prostaglandin E synthase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGN regucalcin
RXRA retinoid X receptor, alpha
S100B S100 calcium binding protein B
SAR1A secretion associated, Ras related GTPase 1A
SARDH sarcosine dehydrogenase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TF transferrin
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TRIB3 tribbles pseudokinase 3
TSC22D1 TSC22 domain family, member 1
TTR transthyretin
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
WEE1 WEE1 G2 checkpoint kinase
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C