pirinixic acid-368 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

191 genes differentially expressed following the pirinixic acid-368 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADIRF adipogenesis regulatory factor
ALAD aminolevulinate dehydratase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARFRP1 ADP-ribosylation factor related protein 1
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATF6 activating transcription factor 6
ATP13A2 ATPase type 13A2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
B3GAT3 beta-1,3-glucuronyltransferase 3
BHLHE40 basic helix-loop-helix family, member e40
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA1 breast cancer 1, early onset
BTBD2 BTB (POZ) domain containing 2
BTD biotinidase
CEP170 centrosomal protein 170kDa
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COBL cordon-bleu WH2 repeat protein
CTC1 CTS telomere maintenance complex component 1
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DHPS deoxyhypusine synthase
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EMC1 ER membrane protein complex subunit 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPHA4 EPH receptor A4
EXOSC9 exosome component 9
FAM114A2 family with sequence similarity 114, member A2
FAM153A family with sequence similarity 153, member A
FANCA Fanconi anemia, complementation group A
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
FXR2 fragile X mental retardation, autosomal homolog 2
GAS7 growth arrest-specific 7
GFOD2 glucose-fructose oxidoreductase domain containing 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GSTM4 glutathione S-transferase mu 4
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H4J histone cluster 1, H4j
HMGA1 high mobility group AT-hook 1
HSPA4 heat shock 70kDa protein 4
HUS1 HUS1 checkpoint homolog (S. pombe)
IL19 interleukin 19
KCTD2 potassium channel tetramerization domain containing 2
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAPK8 mitogen-activated protein kinase 8
MARC1 mitochondrial amidoxime reducing component 1
MPPE1 metallophosphoesterase 1
MPV17 MpV17 mitochondrial inner membrane protein
MRPL35 mitochondrial ribosomal protein L35
MT1HL1 metallothionein 1H-like 1
MXD4 MAX dimerization protein 4
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP210 nucleoporin 210kDa
NUPL2 nucleoporin like 2
PCDHB3 protocadherin beta 3
PCGF1 polycomb group ring finger 1
PEX11A peroxisomal biogenesis factor 11 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRMT7 protein arginine methyltransferase 7
PTEN phosphatase and tensin homolog
PVR poliovirus receptor
RAB3D RAB3D, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RANBP10 RAN binding protein 10
RBM10 RNA binding motif protein 10
RPS11 ribosomal protein S11
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SBF1 SET binding factor 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SGSM3 small G protein signaling modulator 3
SIRPA signal-regulatory protein alpha
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SURF2 surfeit 2
SZRD1 SUZ RNA binding domain containing 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TCEA2 transcription elongation factor A (SII), 2
TMPRSS2 transmembrane protease, serine 2
TNK2 tyrosine kinase, non-receptor, 2
TRIO trio Rho guanine nucleotide exchange factor
TSSC4 tumor suppressing subtransferable candidate 4
TXNRD2 thioredoxin reductase 2
WDR13 WD repeat domain 13
WDR46 WD repeat domain 46
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACPP acid phosphatase, prostate
ADAM23 ADAM metallopeptidase domain 23
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
BNC1 basonuclin 1
CAMKV CaM kinase-like vesicle-associated
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CBX8 chromobox homolog 8
CCDC176 coiled-coil domain containing 176
CCKBR cholecystokinin B receptor
CD101 CD101 molecule
CD2 CD2 molecule
CD53 CD53 molecule
CDH22 cadherin 22, type 2
CEP41 centrosomal protein 41kDa
CHRM2 cholinergic receptor, muscarinic 2
CIDEB cell death-inducing DFFA-like effector b
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CNTNAP1 contactin associated protein 1
CRHBP corticotropin releasing hormone binding protein
CTNNA3 catenin (cadherin-associated protein), alpha 3
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DENND1C DENN/MADD domain containing 1C
ECE2 endothelin converting enzyme 2
F7 coagulation factor VII (serum prothrombin conversion accelerator)
GLRA2 glycine receptor, alpha 2
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GUCA2A guanylate cyclase activator 2A (guanylin)
H2AFY2 H2A histone family, member Y2
HAND1 heart and neural crest derivatives expressed 1
HIST1H1C histone cluster 1, H1c
HIST1H2AB histone cluster 1, H2ab
HMGA2 high mobility group AT-hook 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL10RA interleukin 10 receptor, alpha
IL21 interleukin 21
IQCA1 IQ motif containing with AAA domain 1
KIAA0509 uncharacterized LOC57242
KIAA1549L KIAA1549-like
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL1 kelch-like family member 1
KLHL3 kelch-like family member 3
LEFTY1 left-right determination factor 1
LGALS13 lectin, galactoside-binding, soluble, 13
LIN28A lin-28 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LUZP4 leucine zipper protein 4
MED31 mediator complex subunit 31
MFSD11 major facilitator superfamily domain containing 11
MIP major intrinsic protein of lens fiber
MMP27 matrix metallopeptidase 27
MMP7 matrix metallopeptidase 7
MOXD1 monooxygenase, DBH-like 1
MRPL41 mitochondrial ribosomal protein L41
MT4 metallothionein 4
MYOZ3 myozenin 3
NXPH3 neurexophilin 3
OPRK1 opioid receptor, kappa 1
PCDH17 protocadherin 17
PDZD7 PDZ domain containing 7
PHOX2A paired-like homeobox 2a
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POPDC2 popeye domain containing 2
POPDC3 popeye domain containing 3
PRKG2 protein kinase, cGMP-dependent, type II
REG1B regenerating islet-derived 1 beta
RRH retinal pigment epithelium-derived rhodopsin homolog
S100A1 S100 calcium binding protein A1
S100A2 S100 calcium binding protein A2
SCARA3 scavenger receptor class A, member 3
SCNN1B sodium channel, non voltage gated 1 beta subunit
SDK2 sidekick cell adhesion molecule 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
SYNGR4 synaptogyrin 4
SYNPO synaptopodin
THBS2 thrombospondin 2
TMEM176A transmembrane protein 176A
TMEM40 transmembrane protein 40
TMEM50A transmembrane protein 50A
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
VSIG4 V-set and immunoglobulin domain containing 4
ZBTB39 zinc finger and BTB domain containing 39
ZNF430 zinc finger protein 430