piperacillin-3763 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the piperacillin-3763 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAM22 ADAM metallopeptidase domain 22
AHSP alpha hemoglobin stabilizing protein
AMPH amphiphysin
ANK2 ankyrin 2, neuronal
ANKH ANKH inorganic pyrophosphate transport regulator
ANKRD55 ankyrin repeat domain 55
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP44 Rho GTPase activating protein 44
ATP9A ATPase, class II, type 9A
BAIAP2 BAI1-associated protein 2
BCAS1 breast carcinoma amplified sequence 1
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CCDC121 coiled-coil domain containing 121
CCL22 chemokine (C-C motif) ligand 22
CDK18 cyclin-dependent kinase 18
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CIB2 calcium and integrin binding family member 2
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLPS colipase, pancreatic
CPA3 carboxypeptidase A3 (mast cell)
CT62 cancer/testis antigen 62
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DGKQ diacylglycerol kinase, theta 110kDa
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
EVI5 ecotropic viral integration site 5
FAM63A family with sequence similarity 63, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGB fibrinogen beta chain
FMNL1 formin-like 1
FOLR1 folate receptor 1 (adult)
GGT1 gamma-glutamyltransferase 1
GHRHR growth hormone releasing hormone receptor
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA8A golgin A8 family, member A
GPATCH4 G patch domain containing 4
GPR135 G protein-coupled receptor 135
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
GUCA1B guanylate cyclase activator 1B (retina)
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IDS iduronate 2-sulfatase
IL32 interleukin 32
KALRN kalirin, RhoGEF kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KIF25 kinesin family member 25
KLHL25 kelch-like family member 25
KLK10 kallikrein-related peptidase 10
LINC00260 long intergenic non-protein coding RNA 260
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MLN motilin
MMP13 matrix metallopeptidase 13
MSLN mesothelin
MYH14 myosin, heavy chain 14, non-muscle
NCALD neurocalcin delta
NLRP3 NLR family, pyrin domain containing 3
NMT2 N-myristoyltransferase 2
NUMA1 nuclear mitotic apparatus protein 1
OLFM1 olfactomedin 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSBPL10 oxysterol binding protein-like 10
PARP6 poly (ADP-ribose) polymerase family, member 6
PDE8B phosphodiesterase 8B
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POM121L2 POM121 transmembrane nucleoporin-like 2
PRAMEF10 PRAME family member 10
PSG1 pregnancy specific beta-1-glycoprotein 1
RNF17 ring finger protein 17
RRAD Ras-related associated with diabetes
S100A5 S100 calcium binding protein A5
SCAPER S-phase cyclin A-associated protein in the ER
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOX21 SRY (sex determining region Y)-box 21
SPATA6 spermatogenesis associated 6
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAT2 signal transducer and activator of transcription 2, 113kDa
SYNGR3 synaptogyrin 3
SYT12 synaptotagmin XII
TBC1D2 TBC1 domain family, member 2
TGM4 transglutaminase 4
TNPO2 transportin 2
TNS4 tensin 4
TRIM29 tripartite motif containing 29
TTC22 tetratricopeptide repeat domain 22
TUBB7P tubulin, beta 7, pseudogene
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VIPR2 vasoactive intestinal peptide receptor 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AMT aminomethyltransferase
ANG angiogenin, ribonuclease, RNase A family, 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
AURKC aurora kinase C
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEND5 BEN domain containing 5
BMP4 bone morphogenetic protein 4
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C22ORF46 chromosome 22 open reading frame 46
C5 complement component 5
C8ORF44 chromosome 8 open reading frame 44
CCDC132 coiled-coil domain containing 132
CCDC134 coiled-coil domain containing 134
CD79B CD79b molecule, immunoglobulin-associated beta
CFAP69 cilia and flagella associated protein 69
CHM choroideremia (Rab escort protein 1)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EHD3 EH-domain containing 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA4 EPH receptor A4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GIF gastric intrinsic factor (vitamin B synthesis)
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH2L G patch domain containing 2-like
GPRASP1 G protein-coupled receptor associated sorting protein 1
H2AFJ H2A histone family, member J
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2BM histone cluster 1, H2bm
HSPA1L heat shock 70kDa protein 1-like
IL12A interleukin 12A
IRF1 interferon regulatory factor 1
ITPKA inositol-trisphosphate 3-kinase A
KDM8 lysine (K)-specific demethylase 8
KIFC1 kinesin family member C1
KRT8P12 keratin 8 pseudogene 12
LAMC3 laminin, gamma 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LY86 lymphocyte antigen 86
MLYCD malonyl-CoA decarboxylase
MYLK myosin light chain kinase
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NEK11 NIMA-related kinase 11
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NT5M 5',3'-nucleotidase, mitochondrial
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAIP2B poly(A) binding protein interacting protein 2B
PDE12 phosphodiesterase 12
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGP phosphoglycolate phosphatase
PILRB paired immunoglobin-like type 2 receptor beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL2 podocalyxin-like 2
PTPRS protein tyrosine phosphatase, receptor type, S
QPCTL glutaminyl-peptide cyclotransferase-like
RFPL3 ret finger protein-like 3
RGCC regulator of cell cycle
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF220 ring finger protein 220
SAMD9 sterile alpha motif domain containing 9
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC22A14 solute carrier family 22, member 14
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAOK1 TAO kinase 1
TFCP2L1 transcription factor CP2-like 1
TIGD6 tigger transposable element derived 6
TMEM159 transmembrane protein 159
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRABD TraB domain containing
USP20 ubiquitin specific peptidase 20
VEZT vezatin, adherens junctions transmembrane protein
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YPEL1 yippee-like 1 (Drosophila)
ZNF140 zinc finger protein 140
ZNF197 zinc finger protein 197
ZNF205 zinc finger protein 205
ZNF222 zinc finger protein 222
ZNF385D zinc finger protein 385D
ZNF428 zinc finger protein 428