pipenzolate bromide-4484 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pipenzolate bromide-4484 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL6B actin-like 6B
AK1 adenylate kinase 1
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BAAT bile acid CoA:amino acid N-acyltransferase
BAIAP3 BAI1-associated protein 3
BEST2 bestrophin 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BTG2 BTG family, member 2
C16ORF58 chromosome 16 open reading frame 58
C21ORF2 chromosome 21 open reading frame 2
C3AR1 complement component 3a receptor 1
CAPN10 calpain 10
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CTIF CBP80/20-dependent translation initiation factor
CTNND2 catenin (cadherin-associated protein), delta 2
CUZD1 CUB and zona pellucida-like domains 1
DSTYK dual serine/threonine and tyrosine protein kinase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ECE1 endothelin converting enzyme 1
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
FBLN1 fibulin 1
FBXO11 F-box protein 11
FUBP1 far upstream element (FUSE) binding protein 1
GAB1 GRB2-associated binding protein 1
GRK5 G protein-coupled receptor kinase 5
HAPLN1 hyaluronan and proteoglycan link protein 1
HHLA1 HERV-H LTR-associating 1
HOMER3 homer scaffolding protein 3
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICOSLG inducible T-cell co-stimulator ligand
IGLJ3 immunoglobulin lambda joining 3
ITGA7 integrin, alpha 7
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0319L KIAA0319-like
KIAA1467 KIAA1467
KLHL22 kelch-like family member 22
LAX1 lymphocyte transmembrane adaptor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIPE lipase, hormone-sensitive
MAPK14 mitogen-activated protein kinase 14
MIA melanoma inhibitory activity
MINK1 misshapen-like kinase 1
NCALD neurocalcin delta
NCLN nicalin
NEK9 NIMA-related kinase 9
NPY neuropeptide Y
OPRL1 opiate receptor-like 1
PAOX polyamine oxidase (exo-N4-amino)
PDE4DIP phosphodiesterase 4D interacting protein
PGK2 phosphoglycerate kinase 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIPOX pipecolic acid oxidase
PLCG1 phospholipase C, gamma 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDX2 peroxiredoxin 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTPRU protein tyrosine phosphatase, receptor type, U
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RECQL5 RecQ protein-like 5
RNF17 ring finger protein 17
RPLP2 ribosomal protein, large, P2
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SELPLG selectin P ligand
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLA Src-like-adaptor
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC45A2 solute carrier family 45, member 2
SMAD6 SMAD family member 6
SPHK2 sphingosine kinase 2
SRSF7 serine/arginine-rich splicing factor 7
STOML1 stomatin (EPB72)-like 1
TAOK2 TAO kinase 2
TBKBP1 TBK1 binding protein 1
TCP10L t-complex 10-like
TEF thyrotrophic embryonic factor
TEP1 telomerase-associated protein 1
TET3 tet methylcytosine dioxygenase 3
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TLR2 toll-like receptor 2
TPM3 tropomyosin 3
TRIM10 tripartite motif containing 10
TSC22D2 TSC22 domain family, member 2
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAV1 vav 1 guanine nucleotide exchange factor
WIPF1 WAS/WASL interacting protein family, member 1
ZNF343 zinc finger protein 343
ZNF510 zinc finger protein 510
ZNF652 zinc finger protein 652
ZNF780B zinc finger protein 780B

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACAD10 acyl-CoA dehydrogenase family, member 10
ACBD4 acyl-CoA binding domain containing 4
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARMCX4 armadillo repeat containing, X-linked 4
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
BFSP1 beaded filament structural protein 1, filensin
BMP15 bone morphogenetic protein 15
C17ORF70 chromosome 17 open reading frame 70
C1QTNF1 C1q and tumor necrosis factor related protein 1
CCDC106 coiled-coil domain containing 106
CCDC85C coiled-coil domain containing 85C
CCDC9 coiled-coil domain containing 9
CCL27 chemokine (C-C motif) ligand 27
CCRL2 chemokine (C-C motif) receptor-like 2
CD101 CD101 molecule
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDN dendrin
DEPTOR DEP domain containing MTOR-interacting protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EDIL3 EGF-like repeats and discoidin I-like domains 3
EXD3 exonuclease 3'-5' domain containing 3
EYA4 EYA transcriptional coactivator and phosphatase 4
GAS8 growth arrest-specific 8
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2BJ histone cluster 1, H2bj
HLA-DMA major histocompatibility complex, class II, DM alpha
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL33 interleukin 33
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT86 keratin 86, type II
LOC100287590 uncharacterized LOC100287590
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
MEIS1 Meis homeobox 1
MFAP2 microfibrillar-associated protein 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYO1F myosin IF
NEK11 NIMA-related kinase 11
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NME5 NME/NM23 family member 5
NTSR1 neurotensin receptor 1 (high affinity)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PEX26 peroxisomal biogenesis factor 26
PLXNA3 plexin A3
POM121 POM121 transmembrane nucleoporin
RABL6 RAB, member RAS oncogene family-like 6
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A3 S100 calcium binding protein A3
SCD5 stearoyl-CoA desaturase 5
SCIN scinderin
SERGEF secretion regulating guanine nucleotide exchange factor
SLC12A8 solute carrier family 12, member 8
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMR3A submaxillary gland androgen regulated protein 3A
SND1-IT1 SND1 intronic transcript 1
SNPH syntaphilin
SYT17 synaptotagmin XVII
TEX15 testis expressed 15
TM7SF2 transmembrane 7 superfamily member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM183A transmembrane protein 183A
TMEM8B transmembrane protein 8B
TMSB15A thymosin beta 15a
TRAIP TRAF interacting protein
TRAPPC6A trafficking protein particle complex 6A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL7 tubulin tyrosine ligase-like family member 7
VEZT vezatin, adherens junctions transmembrane protein
VN1R1 vomeronasal 1 receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF205 zinc finger protein 205
ZNF280D zinc finger protein 280D
ZNHIT2 zinc finger, HIT-type containing 2