pipemidic acid-6752 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the pipemidic acid-6752 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
AKR1C4 aldo-keto reductase family 1, member C4
ANKLE2 ankyrin repeat and LEM domain containing 2
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ATF5 activating transcription factor 5
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BGN biglycan
BTG2 BTG family, member 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CDC14A cell division cycle 14A
CDK13 cyclin-dependent kinase 13
CEL carboxyl ester lipase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRND cholinergic receptor, nicotinic, delta (muscle)
CLTB clathrin, light chain B
COL3A1 collagen, type III, alpha 1
CORO2B coronin, actin binding protein, 2B
CTSS cathepsin S
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DCHS2 dachsous cadherin-related 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EFR3B EFR3 homolog B (S. cerevisiae)
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FCAR Fc fragment of IgA receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLOT1 flotillin 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GALR2 galanin receptor 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH4 G patch domain containing 4
GPR135 G protein-coupled receptor 135
GPR35 G protein-coupled receptor 35
GSTM5 glutathione S-transferase mu 5
GUK1 guanylate kinase 1
HCRTR2 hypocretin (orexin) receptor 2
IFNA16 interferon, alpha 16
IFT27 intraflagellar transport 27
IGLJ3 immunoglobulin lambda joining 3
IL11 interleukin 11
IL16 interleukin 16
IL18R1 interleukin 18 receptor 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRAS Kirsten rat sarcoma viral oncogene homolog
LDB1 LIM domain binding 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LMOD1 leiomodin 1 (smooth muscle)
LPL lipoprotein lipase
NAT6 N-acetyltransferase 6 (GCN5-related)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NLE1 notchless homolog 1 (Drosophila)
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRF1 nuclear respiratory factor 1
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PAX8 paired box 8
PDE7B phosphodiesterase 7B
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PKNOX2 PBX/knotted 1 homeobox 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRAMEF11 PRAME family member 11
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PVT1 Pvt1 oncogene (non-protein coding)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RBMS2 RNA binding motif, single stranded interacting protein 2
RDH8 retinol dehydrogenase 8 (all-trans)
RGS10 regulator of G-protein signaling 10
RIN3 Ras and Rab interactor 3
RND1 Rho family GTPase 1
RPL14 ribosomal protein L14
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS3A ribosomal protein S3A
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
S100A13 S100 calcium binding protein A13
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SP100 SP100 nuclear antigen
SYCP2 synaptonemal complex protein 2
SYN2 synapsin II
TENM1 teneurin transmembrane protein 1
THSD4 thrombospondin, type I, domain containing 4
TMEM180 transmembrane protein 180
TPM3 tropomyosin 3
TRIM3 tripartite motif containing 3
TTC9 tetratricopeptide repeat domain 9
UBA7 ubiquitin-like modifier activating enzyme 7
VGLL3 vestigial-like family member 3
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
YIPF4 Yip1 domain family, member 4

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ADAM2 ADAM metallopeptidase domain 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCAS3 breast carcinoma amplified sequence 3
BCORL1 BCL6 corepressor-like 1
BEX4 brain expressed, X-linked 4
C1QTNF1 C1q and tumor necrosis factor related protein 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNO cyclin O
CCNT1 cyclin T1
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC37L1 cell division cycle 37-like 1
CDK6 cyclin-dependent kinase 6
CHM choroideremia (Rab escort protein 1)
CNTLN centlein, centrosomal protein
COMMD10 COMM domain containing 10
CORO1A coronin, actin binding protein, 1A
CPNE7 copine VII
CPZ carboxypeptidase Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC5 exocyst complex component 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL7 F-box and leucine-rich repeat protein 7
FKBP5 FK506 binding protein 5
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS3 fibroblast growth factor receptor substrate 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GTF2I general transcription factor IIi
HELZ helicase with zinc finger
HIST1H2BN histone cluster 1, H2bn
HIST1H3G histone cluster 1, H3g
HIST1H4E histone cluster 1, H4e
HOOK1 hook microtubule-tethering protein 1
HP1BP3 heterochromatin protein 1, binding protein 3
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IPO8 importin 8
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
KRT6A keratin 6A, type II
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LOC257152 uncharacterized LOC257152
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTSS1L metastasis suppressor 1-like
NEK11 NIMA-related kinase 11
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OSBP2 oxysterol binding protein 2
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCOLCE procollagen C-endopeptidase enhancer
PLCD1 phospholipase C, delta 1
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PRR4 proline rich 4 (lacrimal)
PTPRS protein tyrosine phosphatase, receptor type, S
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHOBTB2 Rho-related BTB domain containing 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCIN scinderin
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STK16 serine/threonine kinase 16
THBS3 thrombospondin 3
TUBB2B tubulin, beta 2B class IIb
TXLNG taxilin gamma
UGT8 UDP glycosyltransferase 8
USP19 ubiquitin specific peptidase 19
WNT7A wingless-type MMTV integration site family, member 7A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT3 zinc finger, matrin-type 3
ZNF215 zinc finger protein 215
ZNF385D zinc finger protein 385D
ZNF675 zinc finger protein 675
ZW10 zw10 kinetochore protein