pipemidic acid-3093 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the pipemidic acid-3093 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACSF2 acyl-CoA synthetase family member 2
ACVR1B activin A receptor, type IB
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDOB aldolase B, fructose-bisphosphate
AP1M2 adaptor-related protein complex 1, mu 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARMC9 armadillo repeat containing 9
ATF5 activating transcription factor 5
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BHMT2 betaine--homocysteine S-methyltransferase 2
C20ORF27 chromosome 20 open reading frame 27
CAT catalase
CCKAR cholecystokinin A receptor
CCL22 chemokine (C-C motif) ligand 22
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CLTC clathrin, heavy chain (Hc)
COMT catechol-O-methyltransferase
COPE coatomer protein complex, subunit epsilon
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DLC1 DLC1 Rho GTPase activating protein
DNM2 dynamin 2
FAS Fas cell surface death receptor
FBN1 fibrillin 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOSL2 FOS-like antigen 2
FSCN3 fascin actin-bundling protein 3, testicular
FSTL1 follistatin-like 1
GATA4 GATA binding protein 4
GDF5 growth differentiation factor 5
GKN1 gastrokine 1
GRM6 glutamate receptor, metabotropic 6
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HNF4A hepatocyte nuclear factor 4, alpha
HRASLS2 HRAS-like suppressor 2
IGKV1D-13 immunoglobulin kappa variable 1D-13
IMPG2 interphotoreceptor matrix proteoglycan 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPK1 inositol-tetrakisphosphate 1-kinase
ITPKA inositol-trisphosphate 3-kinase A
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KHK ketohexokinase (fructokinase)
KLF6 Kruppel-like factor 6
LGALS4 lectin, galactoside-binding, soluble, 4
LTBP1 latent transforming growth factor beta binding protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAST2 microtubule associated serine/threonine kinase 2
MINK1 misshapen-like kinase 1
MIP major intrinsic protein of lens fiber
MLXIP MLX interacting protein
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MPPE1 metallophosphoesterase 1
MUC1 mucin 1, cell surface associated
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NR2F2 nuclear receptor subfamily 2, group F, member 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PARVB parvin, beta
PCDHGB6 protocadherin gamma subfamily B, 6
PCNX pecanex homolog (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGAP3 post-GPI attachment to proteins 3
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCL2 phospholipase C-like 2
POU3F2 POU class 3 homeobox 2
PRAMEF11 PRAME family member 11
PRICKLE3 prickle homolog 3 (Drosophila)
PRY PTPN13-like, Y-linked
RAB33A RAB33A, member RAS oncogene family
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCIN scinderin
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLMO1 slowmo homolog 1 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATA2L spermatogenesis associated 2-like
SPRR1B small proline-rich protein 1B
SRSF7 serine/arginine-rich splicing factor 7
STARD13 StAR-related lipid transfer (START) domain containing 13
TERT telomerase reverse transcriptase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM176B transmembrane protein 176B
TSKU tsukushi, small leucine rich proteoglycan
VSIG10 V-set and immunoglobulin domain containing 10
XAB2 XPA binding protein 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZC3H13 zinc finger CCCH-type containing 13
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AKTIP AKT interacting protein
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC6 armadillo repeat containing 6
ASB13 ankyrin repeat and SOCS box containing 13
ASPN asporin
ATAD5 ATPase family, AAA domain containing 5
BCL7A B-cell CLL/lymphoma 7A
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C14ORF93 chromosome 14 open reading frame 93
C1ORF56 chromosome 1 open reading frame 56
C1RL complement component 1, r subcomponent-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC25 coiled-coil domain containing 25
CD3EAP CD3e molecule, epsilon associated protein
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPT centromere protein T
CHKB choline kinase beta
CHM choroideremia (Rab escort protein 1)
CLGN calmegin
CLUH clustered mitochondria (cluA/CLU1) homolog
CRIP1 cysteine-rich protein 1 (intestinal)
CRYL1 crystallin, lambda 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DEPDC1 DEP domain containing 1
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DPY19L2P2 DPY19L2 pseudogene 2
ENAH enabled homolog (Drosophila)
EPS8 epidermal growth factor receptor pathway substrate 8
ERCC3 excision repair cross-complementation group 3
FHOD1 formin homology 2 domain containing 1
FLCN folliculin
FOXN2 forkhead box N2
GPR19 G protein-coupled receptor 19
GPR22 G protein-coupled receptor 22
GPR3 G protein-coupled receptor 3
GRWD1 glutamate-rich WD repeat containing 1
IER3IP1 immediate early response 3 interacting protein 1
IL4R interleukin 4 receptor
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0319L KIAA0319-like
KLHDC4 kelch domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
MAGOHB mago-nashi homolog B (Drosophila)
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MLYCD malonyl-CoA decarboxylase
MTMR12 myotubularin related protein 12
MXD3 MAX dimerization protein 3
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NUPR1 nuclear protein, transcriptional regulator, 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PMCH pro-melanin-concentrating hormone
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRAF2 PRA1 domain family, member 2
PROS1 protein S (alpha)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB23 RAB23, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RCAN3 RCAN family member 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF25 ring finger protein 25
RPL13P5 ribosomal protein L13 pseudogene 5
RWDD2A RWD domain containing 2A
S100A12 S100 calcium binding protein A12
SCGB2A2 secretoglobin, family 2A, member 2
SCRN3 secernin 3
SLC16A4 solute carrier family 16, member 4
SNIP1 Smad nuclear interacting protein 1
SREK1IP1 SREK1-interacting protein 1
ST7L suppression of tumorigenicity 7 like
STARD8 StAR-related lipid transfer (START) domain containing 8
STRA13 stimulated by retinoic acid 13
TAS2R10 taste receptor, type 2, member 10
THBS3 thrombospondin 3
TM7SF2 transmembrane 7 superfamily member 2
TMC5 transmembrane channel-like 5
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNNT1 troponin T type 1 (skeletal, slow)
TPM3 tropomyosin 3
TPRA1 transmembrane protein, adipocyte asscociated 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
ULK1 unc-51 like autophagy activating kinase 1
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WWC2 WW and C2 domain containing 2
ZHX2 zinc fingers and homeoboxes 2
ZNF215 zinc finger protein 215
ZNF862 zinc finger protein 862