pindolol-4496 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pindolol-4496 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRA2 adhesion G protein-coupled receptor A2
AMPD3 adenosine monophosphate deaminase 3
ANP32A-IT1 ANP32A intronic transcript 1
AQP3 aquaporin 3 (Gill blood group)
ASPN asporin
ATM ATM serine/threonine kinase
ATP9B ATPase, class II, type 9B
B9D2 B9 protein domain 2
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF105 chromosome 14 open reading frame 105
C2CD2L C2CD2-like
CA9 carbonic anhydrase IX
CCP110 centriolar coiled coil protein 110kDa
CD68 CD68 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP152 centrosomal protein 152kDa
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPA2 carboxypeptidase A2 (pancreatic)
CREB3L1 cAMP responsive element binding protein 3-like 1
CUZD1 CUB and zona pellucida-like domains 1
DMPK dystrophia myotonica-protein kinase
DOCK10 dedicator of cytokinesis 10
ECE1 endothelin converting enzyme 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVI2A ecotropic viral integration site 2A
FAM63B family with sequence similarity 63, member B
FUT2 fucosyltransferase 2 (secretor status included)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLB1L galactosidase, beta 1-like
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPATCH4 G patch domain containing 4
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GYG2 glycogenin 2
HCRP1 hepatocellular carcinoma-related HCRP1
HHAT hedgehog acyltransferase
HIRA histone cell cycle regulator
HR hair growth associated
HSPG2 heparan sulfate proteoglycan 2
IDI2-AS1 IDI2 antisense RNA 1
IFITM1 interferon induced transmembrane protein 1
IL22 interleukin 22
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNIP1 Kv channel interacting protein 1
KCTD14 potassium channel tetramerization domain containing 14
KIAA0391 KIAA0391
KIRREL kin of IRRE like (Drosophila)
KLHL22 kelch-like family member 22
LATS1 large tumor suppressor kinase 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP11 matrix metallopeptidase 11
NTF3 neurotrophin 3
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OMG oligodendrocyte myelin glycoprotein
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PACS1 phosphofurin acidic cluster sorting protein 1
PDCD6 programmed cell death 6
PEX16 peroxisomal biogenesis factor 16
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G10 phospholipase A2, group X
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKCE protein kinase C, epsilon
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RANBP1 RAN binding protein 1
REPS1 RALBP1 associated Eps domain containing 1
RGS4 regulator of G-protein signaling 4
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL35A ribosomal protein L35a
S100A13 S100 calcium binding protein A13
S1PR1 sphingosine-1-phosphate receptor 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SFTPB surfactant protein B
SIGLEC7 sialic acid binding Ig-like lectin 7
SLMO1 slowmo homolog 1 (Drosophila)
SPATS2L spermatogenesis associated, serine-rich 2-like
STRA6 stimulated by retinoic acid 6
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBL1X transducin (beta)-like 1X-linked
TEX13A testis expressed 13A
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLDC1 TBC/LysM-associated domain containing 1
TMEM212 transmembrane protein 212
TMEM231 transmembrane protein 231
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM3 tripartite motif containing 3
USP29 ubiquitin specific peptidase 29
WDR62 WD repeat domain 62
ZNF235 zinc finger protein 235
ZNF407 zinc finger protein 407
ZNF652 zinc finger protein 652
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADGRB2 adhesion G protein-coupled receptor B2
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARMCX4 armadillo repeat containing, X-linked 4
ASB7 ankyrin repeat and SOCS box containing 7
ATG10 autophagy related 10
AURKC aurora kinase C
C14ORF93 chromosome 14 open reading frame 93
CAPN5 calpain 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNO cyclin O
CCNT1 cyclin T1
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CES3 carboxylesterase 3
CHM choroideremia (Rab escort protein 1)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CISH cytokine inducible SH2-containing protein
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CTSD cathepsin D
DCLRE1A DNA cross-link repair 1A
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGF epidermal growth factor
FAM120C family with sequence similarity 120C
FBXL7 F-box and leucine-rich repeat protein 7
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FMO4 flavin containing monooxygenase 4
FSD1 fibronectin type III and SPRY domain containing 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMPR guanosine monophosphate reductase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRB7 growth factor receptor-bound protein 7
GRPR gastrin-releasing peptide receptor
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA1 homeobox A1
HYAL3 hyaluronoglucosaminidase 3
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
ISYNA1 inositol-3-phosphate synthase 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPTN kaptin (actin binding protein)
LINS lines homolog (Drosophila)
LMAN1 lectin, mannose-binding, 1
LMO7 LIM domain 7
LOC257152 uncharacterized LOC257152
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRC6 leucine rich repeat containing 6
LY86 lymphocyte antigen 86
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFSD6 major facilitator superfamily domain containing 6
MRPL44 mitochondrial ribosomal protein L44
MUC3A mucin 3A, cell surface associated
MYO1F myosin IF
NPFFR1 neuropeptide FF receptor 1
NRTN neurturin
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP3 poly (ADP-ribose) polymerase family, member 3
PER3 period circadian clock 3
RNF39 ring finger protein 39
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMR3A submaxillary gland androgen regulated protein 3A
SPIDR scaffolding protein involved in DNA repair
SRD5A3 steroid 5 alpha-reductase 3
STON1 stonin 1
STRN striatin, calmodulin binding protein
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAOK1 TAO kinase 1
TEX40 testis expressed 40
THOP1 thimet oligopeptidase 1
TMSB15A thymosin beta 15a
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USP19 ubiquitin specific peptidase 19
WDR25 WD repeat domain 25
ZNF197 zinc finger protein 197
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF510 zinc finger protein 510
ZNF667 zinc finger protein 667
ZNF702P zinc finger protein 702, pseudogene
ZSCAN31 zinc finger and SCAN domain containing 31