pigment granule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. (Gene Ontology, GO_0048770)
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Genes

213 proteins co-occuring with the pigment granule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TYR tyrosinase 3.64655
TYRP1 tyrosinase-related protein 1 2.62692
PMEL premelanosome protein 2.56889
RAB27A RAB27A, member RAS oncogene family 2.21565
MLPH melanophilin 2.15006
DCT dopachrome tautomerase 2.017
MYO5A myosin VA (heavy chain 12, myoxin) 1.97132
MLANA melan-A 1.80707
MITF microphthalmia-associated transcription factor 1.76561
HPS1 Hermansky-Pudlak syndrome 1 1.72745
OCA2 oculocutaneous albinism II 1.69216
HPS3 Hermansky-Pudlak syndrome 3 1.53896
GPR143 G protein-coupled receptor 143 1.5113
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 1.50791
RAB38 RAB38, member RAS oncogene family 1.50057
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 1.38738
HPS5 Hermansky-Pudlak syndrome 5 1.33793
HPS4 Hermansky-Pudlak syndrome 4 1.31573
GPNMB glycoprotein (transmembrane) nmb 1.28676
RAB32 RAB32, member RAS oncogene family 1.28569
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.25864
MYO7A myosin VIIA 1.23766
SLC45A2 solute carrier family 45, member 2 1.22776
HPS6 Hermansky-Pudlak syndrome 6 1.2262
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.22257
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.17209
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 1.09442
LYST lysosomal trafficking regulator 1.04884
POMC proopiomelanocortin 1.03479
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 1.0243
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 0.989759
FAM3C family with sequence similarity 3, member C 0.963588
ENO2 enolase 2 (gamma, neuronal) 0.961667
SYTL2 synaptotagmin-like 2 0.959748
MREG melanoregulin 0.954961
LAMP1 lysosomal-associated membrane protein 1 0.906926
EDN3 endothelin 3 0.900426
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 0.858473
CD63 CD63 molecule 0.794229
SYTL4 synaptotagmin-like 4 0.781869
SLC35D3 solute carrier family 35, member D3 0.777298
ASIP agouti signaling protein 0.777298
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.774101
RAB27B RAB27B, member RAS oncogene family 0.739614
KITLG KIT ligand 0.71857
MYRIP myosin VIIA and Rab interacting protein 0.700423
CD68 CD68 molecule 0.697344
CANX calnexin 0.693832
MNT MAX network transcriptional repressor 0.647003
RPH3A rabphilin 3A 0.638434
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.61883
TH tyrosine hydroxylase 0.609086
DTNBP1 dystrobrevin binding protein 1 0.596435
SYP synaptophysin 0.596014
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.591392
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.590133
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.587199
ACPP acid phosphatase, prostate 0.584268
APOPT1 apoptogenic 1, mitochondrial 0.575078
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.571745
CD34 CD34 molecule 0.565923
TBC1D10A TBC1 domain family, member 10A 0.564262
DCTN1 dynactin 1 0.555973
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.552251
RAB21 RAB21, member RAS oncogene family 0.551012
DPH2 DPH2 homolog (S. cerevisiae) 0.540706
RABGGTA Rab geranylgeranyltransferase, alpha subunit 0.532078
FGF7 fibroblast growth factor 7 0.520206
SHROOM2 shroom family member 2 0.520206
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.516124
IGLV9-49 immunoglobulin lambda variable 9-49 0.503912
KIF13A kinesin family member 13A 0.502288
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.500258
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.460401
UBAC1 UBA domain containing 1 0.456809
RHO rhodopsin 0.451631
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 0.450438
RAB17 RAB17, member RAS oncogene family 0.449643
POU3F2 POU class 3 homeobox 2 0.446465
KRT20 keratin 20, type I 0.444085
KRT14 keratin 14, type I 0.442104
PAX6 paired box 6 0.441312
RAB3A RAB3A, member RAS oncogene family 0.440124
TP53 tumor protein p53 0.438542
PAH phenylalanine hydroxylase 0.43696
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.434591
XG Xg blood group 0.433407
NF1 neurofibromin 1 0.425924
HLA-A major histocompatibility complex, class I, A 0.423174
MSH4 mutS homolog 4 0.422782
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.421997
EDNRB endothelin receptor type B 0.419644
NCAPG non-SMC condensin I complex, subunit G 0.40675
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.403637
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.398587
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.397423
THEM5 thioesterase superfamily member 5 0.395873
RILPL1 Rab interacting lysosomal protein-like 1 0.387365
RILP Rab interacting lysosomal protein 0.383895
KRT7 keratin 7, type II 0.380814
PTX4 pentraxin 4, long 0.378122
VAMP7 vesicle-associated membrane protein 7 0.375434
RPE65 retinal pigment epithelium-specific protein 65kDa 0.375434
KLK7 kallikrein-related peptidase 7 0.372366
SLC35G5 solute carrier family 35, member G5 0.366623
RAB8A RAB8A, member RAS oncogene family 0.366241
SNAPIN SNAP-associated protein 0.365477
KRT5 keratin 5, type II 0.36204
PAX3 paired box 3 0.360133
PKDREJ polycystin (PKD) family receptor for egg jelly 0.356705
NCAM1 neural cell adhesion molecule 1 0.352901
RAB36 RAB36, member RAS oncogene family 0.349863
CFH complement factor H 0.345314
SHD Src homology 2 domain containing transforming protein D 0.338884
BAGE2 B melanoma antigen family, member 2 0.338884
LYZ lysozyme 0.334356
PMCH pro-melanin-concentrating hormone 0.329084
B3GAT1 beta-1,3-glucuronyltransferase 1 0.322325
KIF25 kinesin family member 25 0.321201
MB myoglobin 0.318205
MAGEA3 melanoma antigen family A3 0.307004
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.303283
F8 coagulation factor VIII, procoagulant component 0.302168
TBC1D20 TBC1 domain family, member 20 0.298455
FOXN1 forkhead box N1 0.297342
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.296972
PRCC papillary renal cell carcinoma (translocation-associated) 0.295489
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.293267
RLBP1 retinaldehyde binding protein 1 0.292897
RAB37 RAB37, member RAS oncogene family 0.287721
UNC13D unc-13 homolog D (C. elegans) 0.286614
SCARB2 scavenger receptor class B, member 2 0.284032
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 0.264946
TCTEX1D4 Tctex1 domain containing 4 0.26239
RAB33A RAB33A, member RAS oncogene family 0.260202
RILPL2 Rab interacting lysosomal protein-like 2 0.260202
GAK cyclin G associated kinase 0.259473
ATF1 activating transcription factor 1 0.256561
FGF2 fibroblast growth factor 2 (basic) 0.25547
MIR203A microRNA 203a 0.253291
ZBTB14 zinc finger and BTB domain containing 14 0.249302
KTN1 kinectin 1 (kinesin receptor) 0.24894
ANTXR1 anthrax toxin receptor 1 0.244601
CAPN8 calpain 8 0.240276
CAPN5 calpain 5 0.238478
RAB5A RAB5A, member RAS oncogene family 0.234891
SCRT1 scratch family zinc finger 1 0.229532
PLXNC1 plexin C1 0.225976
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.224558
CAT catalase 0.22385
GIPC1 GIPC PDZ domain containing family, member 1 0.217861
FURIN furin (paired basic amino acid cleaving enzyme) 0.215412
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.213669
MCOLN3 mucolipin 3 0.211933
LAMP2 lysosomal-associated membrane protein 2 0.209169
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.203699
GYLTL1B glycosyltransferase-like 1B 0.203022
RAB20 RAB20, member RAS oncogene family 0.200999
GUSB glucuronidase, beta 0.198991
IL2RG interleukin 2 receptor, gamma 0.197993
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.19601
GPR162 G protein-coupled receptor 162 0.191135
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.190814
PF4 platelet factor 4 0.18859
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.185777
CTSD cathepsin D 0.183631
SCG5 secretogranin V 0.180634
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.178877
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.177439
TSC2 tuberous sclerosis 2 0.176305
CDC16 cell division cycle 16 0.173814
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.170629
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.169859
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 0.169604
HBA1 hemoglobin, alpha 1 0.167856
RAP2A RAP2A, member of RAS oncogene family 0.166167
MYO10 myosin X 0.165932
HBA2 hemoglobin, alpha 2 0.164315
CLTC clathrin, heavy chain (Hc) 0.16233
RCC1 regulator of chromosome condensation 1 0.161905
RAP2B RAP2B, member of RAS oncogene family 0.161068
GSTO1 glutathione S-transferase omega 1 0.157943
XDH xanthine dehydrogenase 0.138421
CD40LG CD40 ligand 0.136319
F2 coagulation factor II (thrombin) 0.133795
MYDGF myeloid-derived growth factor 0.131548
VWF von Willebrand factor 0.131033
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.130309
PLA2G10 phospholipase A2, group X 0.12859
HDC histidine decarboxylase 0.127768
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.126705
GP6 glycoprotein VI (platelet) 0.126322
CD36 CD36 molecule (thrombospondin receptor) 0.126307
SCARB1 scavenger receptor class B, member 1 0.124463
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.124244
PGF placental growth factor 0.122986
COX5A cytochrome c oxidase subunit Va 0.122552
F5 coagulation factor V (proaccelerin, labile factor) 0.120685
SELL selectin L 0.117527
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.117107
F2R coagulation factor II (thrombin) receptor 0.115348
RBSN rabenosyn, RAB effector 0.114453
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.114242
SHROOM3 shroom family member 3 0.114171
TFEB transcription factor EB 0.11399
UXT ubiquitously-expressed, prefoldin-like chaperone 0.113954
FRY furry homolog (Drosophila) 0.113845
ILVBL ilvB (bacterial acetolactate synthase)-like 0.113627
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.113515
RAB31 RAB31, member RAS oncogene family 0.113515
RAB2A RAB2A, member RAS oncogene family 0.113293
HMGA2 high mobility group AT-hook 2 0.113256
RAB1A RAB1A, member RAS oncogene family 0.112877