picrotoxinin-4842 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the picrotoxinin-4842 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACTL8 actin-like 8
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AQP3 aquaporin 3 (Gill blood group)
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATXN2L ataxin 2-like
B9D1 B9 protein domain 1
BAIAP3 BAI1-associated protein 3
C1ORF56 chromosome 1 open reading frame 56
C1ORF61 chromosome 1 open reading frame 61
C21ORF2 chromosome 21 open reading frame 2
CA1 carbonic anhydrase I
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALD1 caldesmon 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CES3 carboxylesterase 3
COL1A1 collagen, type I, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTNS cystinosin, lysosomal cystine transporter
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDN dendrin
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DLX6 distal-less homeobox 6
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
EPN1 epsin 1
GAMT guanidinoacetate N-methyltransferase
GAS7 growth arrest-specific 7
GLP1R glucagon-like peptide 1 receptor
GM2A GM2 ganglioside activator
GPR1 G protein-coupled receptor 1
HIC2 hypermethylated in cancer 2
HOXA4 homeobox A4
HOXB2 homeobox B2
HSF1 heat shock transcription factor 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
IFNA14 interferon, alpha 14
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
ING2 inhibitor of growth family, member 2
INHBA inhibin, beta A
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KLF4 Kruppel-like factor 4 (gut)
KMT2A lysine (K)-specific methyltransferase 2A
LIMD1 LIM domains containing 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC729164 hCG1732469
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAOB monoamine oxidase B
MCAM melanoma cell adhesion molecule
MEF2D myocyte enhancer factor 2D
MFAP3L microfibrillar-associated protein 3-like
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFX1 nuclear transcription factor, X-box binding 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
ONECUT2 one cut homeobox 2
OSGIN2 oxidative stress induced growth inhibitor family member 2
PCLO piccolo presynaptic cytomatrix protein
PLAC4 placenta-specific 4
PLAUR plasminogen activator, urokinase receptor
PLIN2 perilipin 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
RAB40AL RAB40A, member RAS oncogene family-like
RABGAP1 RAB GTPase activating protein 1
RASIP1 Ras interacting protein 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RRAGB Ras-related GTP binding B
RS1 retinoschisin 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SRSF7 serine/arginine-rich splicing factor 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYCE1L synaptonemal complex central element protein 1-like
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TGM2 transglutaminase 2
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRD T cell receptor delta locus
UBOX5 U-box domain containing 5
UCN urocortin
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VEZT vezatin, adherens junctions transmembrane protein
WDTC1 WD and tetratricopeptide repeats 1
WSCD1 WSC domain containing 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YIPF4 Yip1 domain family, member 4
ZNF280A zinc finger protein 280A
ZNF609 zinc finger protein 609
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACPP acid phosphatase, prostate
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKRD36 ankyrin repeat domain 36
APLP1 amyloid beta (A4) precursor-like protein 1
AR androgen receptor
ARHGAP4 Rho GTPase activating protein 4
ARRB1 arrestin, beta 1
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
B9D2 B9 protein domain 2
BMP15 bone morphogenetic protein 15
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF80 chromosome 11 open reading frame 80
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAPN5 calpain 5
CCNT1 cyclin T1
CDK3 cyclin-dependent kinase 3
CLCN5 chloride channel, voltage-sensitive 5
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRIP1 cysteine-rich protein 1 (intestinal)
CRLF1 cytokine receptor-like factor 1
CXADR coxsackie virus and adenovirus receptor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPK3 death-associated protein kinase 3
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
FAM214B family with sequence similarity 214, member B
FGGY FGGY carbohydrate kinase domain containing
FKBP5 FK506 binding protein 5
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GRB7 growth factor receptor-bound protein 7
HDAC7 histone deacetylase 7
HIST1H2BC histone cluster 1, H2bc
HOXC10 homeobox C10
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HYAL3 hyaluronoglucosaminidase 3
IL2 interleukin 2
INTS9 integrator complex subunit 9
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0319L KIAA0319-like
LOXL3 lysyl oxidase-like 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
METTL16 methyltransferase like 16
MGC12488
MTMR12 myotubularin related protein 12
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCALD neurocalcin delta
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ODF2 outer dense fiber of sperm tails 2
P3H1 prolyl 3-hydroxylase 1
PGPEP1 pyroglutamyl-peptidase I
PITX2 paired-like homeodomain 2
PLA2G10 phospholipase A2, group X
PODXL podocalyxin-like
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS16 protease, serine, 16 (thymus)
RANGRF RAN guanine nucleotide release factor
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF126P1 ring finger protein 126 pseudogene 1
RNF208 ring finger protein 208
S100A2 S100 calcium binding protein A2
SCGB2A2 secretoglobin, family 2A, member 2
SKI SKI proto-oncogene
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLPI secretory leukocyte peptidase inhibitor
SNX15 sorting nexin 15
STARD3 StAR-related lipid transfer (START) domain containing 3
TCP10 t-complex 10
TDRD1 tudor domain containing 1
TMEM104 transmembrane protein 104
TMEM212 transmembrane protein 212
TRIP10 thyroid hormone receptor interactor 10
UBTD1 ubiquitin domain containing 1
UBXN6 UBX domain protein 6
UPK2 uroplakin 2
USP20 ubiquitin specific peptidase 20
VASH2 vasohibin 2
VIM vimentin
ZBTB44 zinc finger and BTB domain containing 44