phosphatidylinositol-3-kinases Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

415 proteins co-occuring with the biological term phosphatidylinositol-3-kinases in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABI1 abl-interactor 1
ACACA acetyl-CoA carboxylase alpha
ACIN1 apoptotic chromatin condensation inducer 1
ACLY ATP citrate lyase
ADAM12 ADAM metallopeptidase domain 12
ADRB2 adrenoceptor beta 2, surface
AFAP1L2 actin filament associated protein 1-like 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALK anaplastic lymphoma receptor tyrosine kinase
ALYREF Aly/REF export factor
AQP2 aquaporin 2 (collecting duct)
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARFIP1 ADP-ribosylation factor interacting protein 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARRB1 arrestin, beta 1
ASIC1 acid sensing (proton gated) ion channel 1
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATXN1 ataxin 1
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAD BCL2-associated agonist of cell death
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMX BMX non-receptor tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
CA9 carbonic anhydrase IX
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD19 CD19 molecule
CD22 CD22 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD300LF CD300 molecule-like family member f
CD37 CD37 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD5 CD5 molecule
CDC25A cell division cycle 25A
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFL1 cofilin 1 (non-muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CNGB3 cyclic nucleotide gated channel beta 3
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COPS6 COP9 signalosome subunit 6
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DLC1 DLC1 Rho GTPase activating protein
DNM1 dynamin 1
DNM2 dynamin 2
DOCK6 dedicator of cytokinesis 6
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EDC3 enhancer of mRNA decapping 3
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESYT1 extended synaptotagmin-like protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZR ezrin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FLII flightless I homolog (Drosophila)
FLNC filamin C, gamma
FLOT1 flotillin 1
FLOT2 flotillin 2
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXA2 forkhead box A2
FOXG1 forkhead box G1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXO6 forkhead box O6
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAP43 growth associated protein 43
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GCM1 glial cells missing homolog 1 (Drosophila)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRB10 growth factor receptor-bound protein 10
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HSF1 heat shock transcription factor 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICAM1 intercellular adhesion molecule 1
ICAM3 intercellular adhesion molecule 3
IFI16 interferon, gamma-inducible protein 16
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1R1 interleukin 1 receptor, type I
IL21R interleukin 21 receptor
IL2RB interleukin 2 receptor, beta
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
ILK integrin-linked kinase
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPPL1 inositol polyphosphate phosphatase-like 1
INSR insulin receptor
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
ITGB4 integrin, beta 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KDR kinase insert domain receptor
KHSRP KH-type splicing regulatory protein
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAT linker for activation of T cells
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIME1 Lck interacting transmembrane adaptor 1
LIMK1 LIM domain kinase 1
LRP1 low density lipoprotein receptor-related protein 1
LRP6 low density lipoprotein receptor-related protein 6
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MKNK1 MAP kinase interacting serine/threonine kinase 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSN moesin
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MXD1 MAX dimerization protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYL12B myosin, light chain 12B, regulatory
MYO5A myosin VA (heavy chain 12, myoxin)
NBN nibrin
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCF1 neutrophil cytosolic factor 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEU3 sialidase 3 (membrane sialidase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OCLN occludin
OSBP oxysterol binding protein
OSBPL9 oxysterol binding protein-like 9
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALLD palladin, cytoskeletal associated protein
PAWR PRKC, apoptosis, WT1, regulator
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDCD6IP programmed cell death 6 interacting protein
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PELP1 proline, glutamate and leucine rich protein 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFN1 profilin 1
PHB prohibitin
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITPNA phosphatidylinositol transfer protein, alpha
PITPNB phosphatidylinositol transfer protein, beta
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PKN1 protein kinase N1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLN phospholamban
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRA protein tyrosine phosphatase, receptor type, A
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD17 RAD17 homolog (S. pombe)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RANBP3 RAN binding protein 3
RARG retinoic acid receptor, gamma
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RDX radixin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RICTOR RPTOR independent companion of MTOR, complex 2
RPA2 replication protein A2, 32kDa
RPLP2 ribosomal protein, large, P2
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPTOR regulatory associated protein of MTOR, complex 1
RUFY1 RUN and FYVE domain containing 1
RUNX2 runt-related transcription factor 2
RYR2 ryanodine receptor 2 (cardiac)
SDC4 syndecan 4
SGK1 serum/glucocorticoid regulated kinase 1
SGK2 serum/glucocorticoid regulated kinase 2
SGK3 serum/glucocorticoid regulated kinase family, member 3
SH2B2 SH2B adaptor protein 2
SH2B3 SH2B adaptor protein 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SKI SKI proto-oncogene
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD5 SMAD family member 5
SMC1A structural maintenance of chromosomes 1A
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRPK2 SRSF protein kinase 2
SRSF1 serine/arginine-rich splicing factor 1
SRSF5 serine/arginine-rich splicing factor 5
SSH1 slingshot protein phosphatase 1
SSTR2 somatostatin receptor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STK4 serine/threonine kinase 4
STXBP3 syntaxin binding protein 3
SYK spleen tyrosine kinase
SYNJ1 synaptojanin 1
SYNJ2 synaptojanin 2
SYTL1 synaptotagmin-like 1
TAL1 T-cell acute lymphocytic leukemia 1
TBC1D4 TBC1 domain family, member 4
TEK TEK tyrosine kinase, endothelial
TELO2 telomere maintenance 2
TGFBR1 transforming growth factor, beta receptor 1
THOC5 THO complex 5
TIAM2 T-cell lymphoma invasion and metastasis 2
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR5 toll-like receptor 5
TNIP1 TNFAIP3 interacting protein 1
TOM1L1 target of myb1 (chicken)-like 1
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USF1 upstream transcription factor 1
USP8 ubiquitin specific peptidase 8
VASP vasodilator-stimulated phosphoprotein
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VCL vinculin
VCP valosin containing protein
VIM vimentin
WAS Wiskott-Aldrich syndrome
WASL Wiskott-Aldrich syndrome-like
WNK1 WNK lysine deficient protein kinase 1
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3HC1 zinc finger, C3HC-type containing 1
ZFYVE16 zinc finger, FYVE domain containing 16