phosphatidylinositol 3-kinase complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too. (Gene Ontology, GO_0005942)
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15 proteins localized to the phosphatidylinositol 3-kinase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.663342
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.663342
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.663342
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.663342
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 0.237908
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 0.237908
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.237908
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.098109
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.098109
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 0.098109
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.098109
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.098109
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.03318
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.03318
VAC14 Vac14 homolog (S. cerevisiae) 0.007697