phosphatidylinositol 3-kinase complex, class iii Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI). (Gene Ontology, GO_0035032)
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59 proteins co-occuring with the phosphatidylinositol 3-kinase complex, class iii cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.16906
BECN1 beclin 1, autophagy related 1.93274
UVRAG UV radiation resistance associated 1.42373
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 1.3543
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.11888
ATG14 autophagy related 14 1.0243
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.904602
NRBF2 nuclear receptor binding factor 2 0.85342
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 0.797436
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.781412
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.738263
ATG9A autophagy related 9A 0.728836
ATG5 autophagy related 5 0.716346
ATG7 autophagy related 7 0.696026
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 0.681155
INPP5J inositol polyphosphate-5-phosphatase J 0.663368
ZFYVE26 zinc finger, FYVE domain containing 26 0.631598
RRAGB Ras-related GTP binding B 0.627335
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.625632
AMBRA1 autophagy/beclin-1 regulator 1 0.603174
KIAA0226 KIAA0226 0.603174
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.593492
TNS1 tensin 1 0.551012
RAB21 RAB21, member RAS oncogene family 0.535772
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.535361
VMP1 vacuole membrane protein 1 0.523476
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.510418
ZFYVE1 zinc finger, FYVE domain containing 1 0.489731
RHEB Ras homolog enriched in brain 0.45004
SGK1 serum/glucocorticoid regulated kinase 1 0.448054
IL24 interleukin 24 0.432618
PTEN phosphatase and tensin homolog 0.431435
MAP1S microtubule-associated protein 1S 0.430253
LRPPRC leucine-rich pentatricopeptide repeat containing 0.41182
DAPK1 death-associated protein kinase 1 0.405193
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.350243
DAP death-associated protein 0.326078
PI3 peptidase inhibitor 3, skin-derived 0.288091
MAP4 microtubule-associated protein 4 0.285876
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.260566
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.256561
PLD1 phospholipase D1, phosphatidylcholine-specific 0.250026
TLR4 toll-like receptor 4 0.245685
CYBB cytochrome b-245, beta polypeptide 0.240996
EPHB2 EPH receptor B2 0.237401
MYD88 myeloid differentiation primary response 88 0.229176
IL13 interleukin 13 0.208825
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.206766
PNPLA2 patatin-like phospholipase domain containing 2 0.200999
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.195025
MAP2 microtubule-associated protein 2 0.191456
TBK1 TANK-binding kinase 1 0.18796
ATG12 autophagy related 12 0.182122
MAPT microtubule-associated protein tau 0.181823
RNF2 ring finger protein 2 0.143624
SNORA29 small nucleolar RNA, H/ACA box 29 0.1426
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.141913
ULK1 unc-51 like autophagy activating kinase 1 0.139382
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.138074