phosphatidylinositol 3-kinase complex, class ib Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks. (Gene Ontology, GO_0005944)
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17 proteins co-occuring with the phosphatidylinositol 3-kinase complex, class ib cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.19259
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.51694
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.19314
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.05136
CCNF cyclin F 0.972263
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 0.924197
IMMT inner membrane protein, mitochondrial 0.773188
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 0.748189
PLEK pleckstrin 0.65259
CCL11 chemokine (C-C motif) ligand 11 0.612471
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.600223
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.352142
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.344556
TNS1 tensin 1 0.326453
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.320826
C5AR1 complement component 5a receptor 1 0.19733
SELE selectin E 0.166405