phosphatidylinositol 3-kinase complex, class i Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast. (Gene Ontology, GO_0097651)
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5 proteins localized to the phosphatidylinositol 3-kinase complex, class i cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.057922
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.057922
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 0.03318
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 0.03318
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.03318