phenindione-7289 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the phenindione-7289 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADGRF5 adhesion G protein-coupled receptor F5
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP5 A kinase (PRKA) anchor protein 5
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMBRA1 autophagy/beclin-1 regulator 1
ANXA2P1 annexin A2 pseudogene 1
APOL6 apolipoprotein L, 6
ASF1A anti-silencing function 1A histone chaperone
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
B9D2 B9 protein domain 2
BBC3 BCL2 binding component 3
BCR breakpoint cluster region
BFSP1 beaded filament structural protein 1, filensin
C16ORF59 chromosome 16 open reading frame 59
CCDC71 coiled-coil domain containing 71
CD52 CD52 molecule
CDH8 cadherin 8, type 2
CDK10 cyclin-dependent kinase 10
CFAP45 cilia and flagella associated protein 45
CIDEC cell death-inducing DFFA-like effector c
CLCN6 chloride channel, voltage-sensitive 6
CPEB1 cytoplasmic polyadenylation element binding protein 1
CXCL3 chemokine (C-X-C motif) ligand 3
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
E2F4 E2F transcription factor 4, p107/p130-binding
EFNA3 ephrin-A3
EPB41 erythrocyte membrane protein band 4.1
FA2H fatty acid 2-hydroxylase
FBXO46 F-box protein 46
FCMR Fc fragment of IgM receptor
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GYPB glycophorin B (MNS blood group)
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIPK3 homeodomain interacting protein kinase 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNF1B HNF1 homeobox B
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFIH1 interferon induced with helicase C domain 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LMNA lamin A/C
LRP1 low density lipoprotein receptor-related protein 1
LRRC61 leucine rich repeat containing 61
MAP7D3 MAP7 domain containing 3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MATN3 matrilin 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MEF2D myocyte enhancer factor 2D
METTL7A methyltransferase like 7A
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFIB nuclear factor I/B
NID2 nidogen 2 (osteonidogen)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR2E3 nuclear receptor subfamily 2, group E, member 3
PAOX polyamine oxidase (exo-N4-amino)
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PRODH2 proline dehydrogenase (oxidase) 2
PRR7 proline rich 7 (synaptic)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVT1 Pvt1 oncogene (non-protein coding)
RAB4B RAB4B, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RTEL1 regulator of telomere elongation helicase 1
SECISBP2 SECIS binding protein 2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMAD7 SMAD family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPP1 secreted phosphoprotein 1
SPTB spectrin, beta, erythrocytic
SS18 synovial sarcoma translocation, chromosome 18
STC1 stanniocalcin 1
STX6 syntaxin 6
SYNJ2 synaptojanin 2
TFR2 transferrin receptor 2
TGFB1 transforming growth factor, beta 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TTLL7 tubulin tyrosine ligase-like family member 7
ZER1 zyg-11 related, cell cycle regulator
ZHX3 zinc fingers and homeoboxes 3
ZNF222 zinc finger protein 222

decreased expression

Symbol Name
ADCY7 adenylate cyclase 7
ADGRF1 adhesion G protein-coupled receptor F1
AGO3 argonaute RISC catalytic component 3
ANAPC2 anaphase promoting complex subunit 2
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD10 ankyrin repeat domain 10
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCAS4 breast carcinoma amplified sequence 4
C19ORF40 chromosome 19 open reading frame 40
CCDC47 coiled-coil domain containing 47
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLEC2B C-type lectin domain family 2, member B
CTSF cathepsin F
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EIF5A2 eukaryotic translation initiation factor 5A2
FAM127B family with sequence similarity 127, member B
FAM131A family with sequence similarity 131, member A
FICD FIC domain containing
FPGS folylpolyglutamate synthase
FZD3 frizzled class receptor 3
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
HMGB3P1 high mobility group box 3 pseudogene 1
HOMER2 homer scaffolding protein 2
IFI6 interferon, alpha-inducible protein 6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
JMJD4 jumonji domain containing 4
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0319L KIAA0319-like
KIFC1 kinesin family member C1
KRT4 keratin 4, type II
KRT6A keratin 6A, type II
MANBA mannosidase, beta A, lysosomal
MAPK12 mitogen-activated protein kinase 12
MED15 mediator complex subunit 15
METTL16 methyltransferase like 16
MGMT O-6-methylguanine-DNA methyltransferase
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MID1IP1 MID1 interacting protein 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MON1B MON1 secretory trafficking family member B
MORC3 MORC family CW-type zinc finger 3
MPI mannose phosphate isomerase
MTRF1 mitochondrial translational release factor 1
NCS1 neuronal calcium sensor 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OTUD3 OTU deubiquitinase 3
P3H2 prolyl 3-hydroxylase 2
PALMD palmdelphin
PCOLCE procollagen C-endopeptidase enhancer
PDIA3 protein disulfide isomerase family A, member 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAC1 placenta-specific 1
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPL periplakin
PTBP2 polypyrimidine tract binding protein 2
PTCD2 pentatricopeptide repeat domain 2
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIN1 Ras and Rab interactor 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPH3AL rabphilin 3A-like (without C2 domains)
SALL2 spalt-like transcription factor 2
SAV1 salvador family WW domain containing protein 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SETD6 SET domain containing 6
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMA4 glucuronidase, beta pseudogene
SNHG20 small nucleolar RNA host gene 20
SREBF1 sterol regulatory element binding transcription factor 1
STARD13 StAR-related lipid transfer (START) domain containing 13
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TMEM159 transmembrane protein 159
TPST1 tyrosylprotein sulfotransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
UBA5 ubiquitin-like modifier activating enzyme 5
WASF1 WAS protein family, member 1
ZBTB39 zinc finger and BTB domain containing 39
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36 ZFP36 ring finger protein
ZNF212 zinc finger protein 212
ZNF230 zinc finger protein 230
ZNF665 zinc finger protein 665
ZXDC ZXD family zinc finger C