phenindione-2868 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the phenindione-2868 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AGO4 argonaute RISC catalytic component 4
AQR aquarius intron-binding spliceosomal factor
ARHGAP33 Rho GTPase activating protein 33
ARID1A AT rich interactive domain 1A (SWI-like)
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BIN1 bridging integrator 1
BTN2A2 butyrophilin, subfamily 2, member A2
C17ORF59 chromosome 17 open reading frame 59
C3ORF18 chromosome 3 open reading frame 18
CAMK1G calcium/calmodulin-dependent protein kinase IG
CCDC85B coiled-coil domain containing 85B
CD47 CD47 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CLEC7A C-type lectin domain family 7, member A
COL19A1 collagen, type XIX, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXCR2 chemokine (C-X-C motif) receptor 2
CYTH1 cytohesin 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DLX2 distal-less homeobox 2
EDNRB endothelin receptor type B
EPHB2 EPH receptor B2
EPX eosinophil peroxidase
ERCC2 excision repair cross-complementation group 2
ERO1LB ERO1-like beta (S. cerevisiae)
ESR2 estrogen receptor 2 (ER beta)
F9 coagulation factor IX
FAM198B family with sequence similarity 198, member B
FBLN1 fibulin 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP8 FK506 binding protein 8, 38kDa
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FXYD5 FXYD domain containing ion transport regulator 5
GJA4 gap junction protein, alpha 4, 37kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAS1 hyaluronan synthase 1
HFE hemochromatosis
HIST1H3E histone cluster 1, H3e
HLA-DMB major histocompatibility complex, class II, DM beta
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IL23A interleukin 23, alpha subunit p19
ITGA8 integrin, alpha 8
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLF8 Kruppel-like factor 8
LAMP1 lysosomal-associated membrane protein 1
LENEP lens epithelial protein
MATN1 matrilin 1, cartilage matrix protein
MFSD7 major facilitator superfamily domain containing 7
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEFL neurofilament, light polypeptide
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OSBPL10 oxysterol binding protein-like 10
PENK proenkephalin
PER1 period circadian clock 1
PKP1 plakophilin 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD1 phospholipase D1, phosphatidylcholine-specific
PRDM10 PR domain containing 10
PROM1 prominin 1
PXN paxillin
RARA retinoic acid receptor, alpha
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A8 S100 calcium binding protein A8
SAA4 serum amyloid A4, constitutive
SDC2 syndecan 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3BP2 SH3-domain binding protein 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMG6 SMG6 nonsense mediated mRNA decay factor
SORBS3 sorbin and SH3 domain containing 3
TBCD tubulin folding cofactor D
TCF3 transcription factor 3
TCP10L t-complex 10-like
TGFA transforming growth factor, alpha
TMLHE trimethyllysine hydroxylase, epsilon
TMPRSS15 transmembrane protease, serine 15
TMPRSS4 transmembrane protease, serine 4
TRIM29 tripartite motif containing 29
TRIM38 tripartite motif containing 38
TRIP11 thyroid hormone receptor interactor 11
TSPAN9 tetraspanin 9
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VPRBP Vpr (HIV-1) binding protein
ZNF286A zinc finger protein 286A
ZNF391 zinc finger protein 391
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ASIC3 acid sensing (proton gated) ion channel 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
BAK1 BCL2-antagonist/killer 1
BCL9 B-cell CLL/lymphoma 9
BCORL1 BCL6 corepressor-like 1
C14ORF93 chromosome 14 open reading frame 93
C1ORF105 chromosome 1 open reading frame 105
C22ORF29 chromosome 22 open reading frame 29
CCDC25 coiled-coil domain containing 25
CDK3 cyclin-dependent kinase 3
CIDEC cell death-inducing DFFA-like effector c
CLDN15 claudin 15
CPPED1 calcineurin-like phosphoesterase domain containing 1
ELMO3 engulfment and cell motility 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM160B2 family with sequence similarity 160, member B2
FBXL6 F-box and leucine-rich repeat protein 6
FER fer (fps/fes related) tyrosine kinase
FFAR2 free fatty acid receptor 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRK fyn-related Src family tyrosine kinase
GEMIN8 gem (nuclear organelle) associated protein 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L2 galactosidase, beta 1-like 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM2 glutathione S-transferase mu 2 (muscle)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4F histone cluster 1, H4f
HIST1H4J histone cluster 1, H4j
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IGFBP6 insulin-like growth factor binding protein 6
IGSF1 immunoglobulin superfamily, member 1
IL17RA interleukin 17 receptor A
INPP1 inositol polyphosphate-1-phosphatase
KLF7 Kruppel-like factor 7 (ubiquitous)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBTD1 mbt domain containing 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAV2 neuron navigator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NES nestin
NPIPB15 nuclear pore complex interacting protein family, member B15
NRGN neurogranin (protein kinase C substrate, RC3)
P3H1 prolyl 3-hydroxylase 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PLCD1 phospholipase C, delta 1
PNRC1 proline-rich nuclear receptor coactivator 1
PRICKLE3 prickle homolog 3 (Drosophila)
RNF2 ring finger protein 2
SCAI suppressor of cancer cell invasion
SHARPIN SHANK-associated RH domain interactor
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SOX12 SRY (sex determining region Y)-box 12
SREBF1 sterol regulatory element binding transcription factor 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STRN4 striatin, calmodulin binding protein 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TARP TCR gamma alternate reading frame protein
TBC1D19 TBC1 domain family, member 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TM6SF1 transmembrane 6 superfamily member 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM115 transmembrane protein 115
TMEM242 transmembrane protein 242
TMEM62 transmembrane protein 62
TRAF2 TNF receptor-associated factor 2
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
UBOX5 U-box domain containing 5
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
USP36 ubiquitin specific peptidase 36
VEGFC vascular endothelial growth factor C
XK X-linked Kx blood group
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF189 zinc finger protein 189
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF571 zinc finger protein 571
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862