phenazopyridine-6100 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the phenazopyridine-6100 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACTC1 actin, alpha, cardiac muscle 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOA4 apolipoprotein A-IV
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARTN artemin
ATXN2L ataxin 2-like
BHMT2 betaine--homocysteine S-methyltransferase 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF12 chromosome 10 open reading frame 12
C14ORF105 chromosome 14 open reading frame 105
CALCB calcitonin-related polypeptide beta
CAMKV CaM kinase-like vesicle-associated
CD4 CD4 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP112 centrosomal protein 112kDa
CLCN6 chloride channel, voltage-sensitive 6
CLCN7 chloride channel, voltage-sensitive 7
CLIC2 chloride intracellular channel 2
CNTNAP2 contactin associated protein-like 2
CRISP2 cysteine-rich secretory protein 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSHL1 chorionic somatomammotropin hormone-like 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEFB126 defensin, beta 126
DFNB31 deafness, autosomal recessive 31
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
EMCN endomucin
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPYC epiphycan
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM134B family with sequence similarity 134, member B
FAM65B family with sequence similarity 65, member B
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FFAR2 free fatty acid receptor 2
FGFBP1 fibroblast growth factor binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GBP2 guanylate binding protein 2, interferon-inducible
GDF5 growth differentiation factor 5
GP5 glycoprotein V (platelet)
GRM7 glutamate receptor, metabotropic 7
GSN gelsolin
GSTA3 glutathione S-transferase alpha 3
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HCAR3 hydroxycarboxylic acid receptor 3
HDAC6 histone deacetylase 6
HFE hemochromatosis
HIST1H4B histone cluster 1, H4b
HNF4A hepatocyte nuclear factor 4, alpha
ICOS inducible T-cell co-stimulator
IFT27 intraflagellar transport 27
IL1B interleukin 1, beta
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LDHB lactate dehydrogenase B
LINC00302 long intergenic non-protein coding RNA 302
LRRC23 leucine rich repeat containing 23
LRRN3 leucine rich repeat neuronal 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCAM melanoma cell adhesion molecule
MRPS18C mitochondrial ribosomal protein S18C
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
MYF5 myogenic factor 5
NOVA2 neuro-oncological ventral antigen 2
NPC1 Niemann-Pick disease, type C1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRXN1 neurexin 1
OGDHL oxoglutarate dehydrogenase-like
OLIG2 oligodendrocyte lineage transcription factor 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PML promyelocytic leukemia
PRUNE2 prune homolog 2 (Drosophila)
PURG purine-rich element binding protein G
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPL23AP53 ribosomal protein L23a pseudogene 53
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A1 S100 calcium binding protein A1
SFTPD surfactant protein D
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMIM14 small integral membrane protein 14
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTA1 syntrophin, alpha 1
SPN sialophorin
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
STS steroid sulfatase (microsomal), isozyme S
THBS3 thrombospondin 3
TNNT3 troponin T type 3 (skeletal, fast)
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
TRH thyrotropin-releasing hormone
TRIM68 tripartite motif containing 68
TRPM2 transient receptor potential cation channel, subfamily M, member 2
VCX2 variable charge, X-linked 2
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADGRG2 adhesion G protein-coupled receptor G2
AMPH amphiphysin
ARPIN actin-related protein 2/3 complex inhibitor
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BHLHE41 basic helix-loop-helix family, member e41
C17ORF80 chromosome 17 open reading frame 80
C22ORF46 chromosome 22 open reading frame 46
C3ORF18 chromosome 3 open reading frame 18
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNO cyclin O
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP164 centrosomal protein 164kDa
CLCF1 cardiotrophin-like cytokine factor 1
COQ3 coenzyme Q3 methyltransferase
CRIP1 cysteine-rich protein 1 (intestinal)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSF1R colony stimulating factor 1 receptor
CXXC4 CXXC finger protein 4
DCAF13 DDB1 and CUL4 associated factor 13
DRD1 dopamine receptor D1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
ETNK2 ethanolamine kinase 2
FAM131A family with sequence similarity 131, member A
FCHSD2 FCH and double SH3 domains 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FILIP1L filamin A interacting protein 1-like
FOXN2 forkhead box N2
FRK fyn-related Src family tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR85 G protein-coupled receptor 85
GRAMD1C GRAM domain containing 1C
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H2AK histone cluster 1, H2ak
HIST1H3B histone cluster 1, H3b
HOXA4 homeobox A4
HSPB6 heat shock protein, alpha-crystallin-related, B6
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KAT2A K(lysine) acetyltransferase 2A
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KLF7 Kruppel-like factor 7 (ubiquitous)
LAX1 lymphocyte transmembrane adaptor 1
LHX1 LIM homeobox 1
LOC729164 hCG1732469
LOXL3 lysyl oxidase-like 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MED31 mediator complex subunit 31
MMP3 matrix metallopeptidase 3
NDOR1 NADPH dependent diflavin oxidoreductase 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5E 5'-nucleotidase, ecto (CD73)
NTF3 neurotrophin 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PDGFD platelet derived growth factor D
PEX26 peroxisomal biogenesis factor 26
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB30 RAB30, member RAS oncogene family
RAB40AL RAB40A, member RAS oncogene family-like
RFPL1S RFPL1 antisense RNA 1
RUSC2 RUN and SH3 domain containing 2
SETD1A SET domain containing 1A
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STIM1 stromal interaction molecule 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBR1 transforming growth factor, beta receptor 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM212 transmembrane protein 212
TMEM242 transmembrane protein 242
TRIM36 tripartite motif containing 36
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBG2 tubulin, gamma 2
UBTD1 ubiquitin domain containing 1
UNC119 unc-119 homolog (C. elegans)
VPS9D1 VPS9 domain containing 1
WDR25 WD repeat domain 25
WDR62 WD repeat domain 62
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP37 ZFP37 zinc finger protein
ZNF711 zinc finger protein 711
ZNF804A zinc finger protein 804A
ZSCAN2 zinc finger and SCAN domain containing 2