phenacetin-2471 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the phenacetin-2471 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABLIM1 actin binding LIM protein 1
ACO2 aconitase 2, mitochondrial
APOC4 apolipoprotein C-IV
ARHGAP44 Rho GTPase activating protein 44
ATP13A2 ATPase type 13A2
BMP7 bone morphogenetic protein 7
C1ORF105 chromosome 1 open reading frame 105
C1ORF95 chromosome 1 open reading frame 95
CARD10 caspase recruitment domain family, member 10
CBX8 chromobox homolog 8
CCDC57 coiled-coil domain containing 57
CCDC71 coiled-coil domain containing 71
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CNN1 calponin 1, basic, smooth muscle
COL9A3 collagen, type IX, alpha 3
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPN2 carboxypeptidase N, polypeptide 2
CPNE7 copine VII
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
CRYGD crystallin, gamma D
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
EHD3 EH-domain containing 3
FCMR Fc fragment of IgM receptor
FGL1 fibrinogen-like 1
FLOT1 flotillin 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GATA3 GATA binding protein 3
GJA4 gap junction protein, alpha 4, 37kDa
GRIK5 glutamate receptor, ionotropic, kainate 5
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HIST1H4A histone cluster 1, H4a
HOXA7 homeobox A7
HRASLS2 HRAS-like suppressor 2
IFNA17 interferon, alpha 17
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
ING1 inhibitor of growth family, member 1
JAK3 Janus kinase 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF3A kinesin family member 3A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT8 keratin 8, type II
KSR1 kinase suppressor of ras 1
LAMP3 lysosomal-associated membrane protein 3
LENEP lens epithelial protein
LIMK1 LIM domain kinase 1
LOXL3 lysyl oxidase-like 3
LTBP1 latent transforming growth factor beta binding protein 1
MFAP3L microfibrillar-associated protein 3-like
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MYOZ3 myozenin 3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NINJ2 ninjurin 2
NPR1 natriuretic peptide receptor 1
OLFM1 olfactomedin 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDIA2 protein disulfide isomerase family A, member 2
PER3 period circadian clock 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G3 phospholipase A2, group III
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRB1 proline-rich protein BstNI subfamily 1
PRELP proline/arginine-rich end leucine-rich repeat protein
PTCRA pre T-cell antigen receptor alpha
PTPRG protein tyrosine phosphatase, receptor type, G
RAB11B RAB11B, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RANBP3 RAN binding protein 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RTEL1 regulator of telomere elongation helicase 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPTBN5 spectrin, beta, non-erythrocytic 5
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SV2B synaptic vesicle glycoprotein 2B
TEF thyrotrophic embryonic factor
TJP3 tight junction protein 3
TK2 thymidine kinase 2, mitochondrial
TRBC1 T cell receptor beta constant 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TTN titin
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WFDC8 WAP four-disulfide core domain 8
WNT16 wingless-type MMTV integration site family, member 16
WRAP53 WD repeat containing, antisense to TP53
ZBTB25 zinc finger and BTB domain containing 25
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACPP acid phosphatase, prostate
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHR aryl hydrocarbon receptor
AIM2 absent in melanoma 2
ANXA2P2 annexin A2 pseudogene 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARMC6 armadillo repeat containing 6
ASGR2 asialoglycoprotein receptor 2
AXIN1 axin 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BNC2 basonuclin 2
C16ORF59 chromosome 16 open reading frame 59
C17ORF53 chromosome 17 open reading frame 53
C17ORF70 chromosome 17 open reading frame 70
CAPN5 calpain 5
CCDC186 coiled-coil domain containing 186
CDCP1 CUB domain containing protein 1
CHM choroideremia (Rab escort protein 1)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DBR1 debranching RNA lariats 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPEP2 dipeptidase 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
FBXO31 F-box protein 31
FGL2 fibrinogen-like 2
FOXN2 forkhead box N2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GPR27 G protein-coupled receptor 27
HIST1H2BI histone cluster 1, H2bi
HPSE heparanase
ICAM5 intercellular adhesion molecule 5, telencephalin
INO80D INO80 complex subunit D
IP6K1 inositol hexakisphosphate kinase 1
IRF2 interferon regulatory factor 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCTD20 potassium channel tetramerization domain containing 20
KLK5 kallikrein-related peptidase 5
LATS1 large tumor suppressor kinase 1
LMAN1 lectin, mannose-binding, 1
LTBP3 latent transforming growth factor beta binding protein 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM4 MDM4, p53 regulator
MRAS muscle RAS oncogene homolog
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NSUN6 NOP2/Sun domain family, member 6
NXPE3 neurexophilin and PC-esterase domain family, member 3
ODF2 outer dense fiber of sperm tails 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHACTR1 phosphatase and actin regulator 1
PLA2G15 phospholipase A2, group XV
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRR14L proline rich 14-like
PRR7 proline rich 7 (synaptic)
PTAFR platelet-activating factor receptor
PTCD1 pentatricopeptide repeat domain 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RETN resistin
RFXAP regulatory factor X-associated protein
RNF122 ring finger protein 122
SCRN3 secernin 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKI SKI proto-oncogene
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SOX12 SRY (sex determining region Y)-box 12
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
STK4 serine/threonine kinase 4
STX11 syntaxin 11
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THEM6 thioesterase superfamily member 6
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN13 tetraspanin 13
TWISTNB TWIST neighbor
TXLNG taxilin gamma
UNC119 unc-119 homolog (C. elegans)
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF350 zinc finger protein 350
ZNF480 zinc finger protein 480
ZNF747 zinc finger protein 747