phagocyte bactericidal dysfunction Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A primary immunodeficiency disease where phagocytes have a diminished ability to fight bacterial infection. (Human Disease Ontology, DOID_3262)
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Genes

65 genes co-occuring with the disease phagocyte bactericidal dysfunction in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CYBB cytochrome b-245, beta polypeptide 2.73685
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.62553
NCF1C neutrophil cytosolic factor 1C pseudogene 2.35201
NCF1 neutrophil cytosolic factor 1 2.33601
CYBA cytochrome b-245, alpha polypeptide 2.10904
NCF2 neutrophil cytosolic factor 2 2.10138
CAT catalase 1.50096
DUOX1 dual oxidase 1 1.39258
DUOX2 dual oxidase 2 1.36902
NCF4 neutrophil cytosolic factor 4, 40kDa 1.28435
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 0.97128
FERMT3 fermitin family member 3 0.873281
GCDH glutaryl-CoA dehydrogenase 0.844211
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.839296
NOXA1 NADPH oxidase activator 1 0.730166
PEX16 peroxisomal biogenesis factor 16 0.724098
NKX6-2 NK6 homeobox 2 0.697109
NOXO1 NADPH oxidase organizer 1 0.678701
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.642615
XK X-linked Kx blood group 0.642221
DAO D-amino-acid oxidase 0.637495
GLYAT glycine-N-acyltransferase 0.630813
MPO myeloperoxidase 0.569552
CD53 CD53 molecule 0.531928
IL4I1 interleukin 4 induced 1 0.528063
CXXC5 CXXC finger protein 5 0.508041
OLFM4 olfactomedin 4 0.457109
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.4443
RASD1 RAS, dexamethasone-induced 1 0.428516
CXCR1 chemokine (C-X-C motif) receptor 1 0.391141
CD34 CD34 molecule 0.362609
RAG2 recombination activating gene 2 0.35892
TADA1 transcriptional adaptor 1 0.352659
AOX1 aldehyde oxidase 1 0.351923
RAP1A RAP1A, member of RAS oncogene family 0.331025
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.33066
SELE selectin E 0.304864
SCAI suppressor of cancer cell invasion 0.298731
CXCR2 chemokine (C-X-C motif) receptor 2 0.270464
GZMM granzyme M (lymphocyte met-ase 1) 0.263722
LST1 leukocyte specific transcript 1 0.259124
IDO1 indoleamine 2,3-dioxygenase 1 0.257005
CD226 CD226 molecule 0.232836
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.207245
SELL selectin L 0.201308
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.184128
IL2RG interleukin 2 receptor, gamma 0.178682
CD4 CD4 molecule 0.171036
FXYD5 FXYD domain containing ion transport regulator 5 0.166995
LMO2 LIM domain only 2 (rhombotin-like 1) 0.166768
SRI sorcin 0.164571
LBR lamin B receptor 0.160203
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.144799
ESAM endothelial cell adhesion molecule 0.144278
SP1 Sp1 transcription factor 0.143837
FYN FYN proto-oncogene, Src family tyrosine kinase 0.143834
VCAM1 vascular cell adhesion molecule 1 0.143743
ICAM1 intercellular adhesion molecule 1 0.143436
EDA ectodysplasin A 0.142826
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.142291
C3 complement component 3 0.142091
SMAD2 SMAD family member 2 0.141424
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.141424
CXCL12 chemokine (C-X-C motif) ligand 12 0.138015
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.136361