personality disorder Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A disease of mental health that involve long-term patterns of thoughts and behaviors that cause serious problems with relationships and work. (Human Disease Ontology, DOID_1510)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0012075
Similar Terms
Downloads & Tools

Genes

301 genes associated with the personality disorder phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
PLCE1 phospholipase C, epsilon 1 1.18704
KATNAL2 katanin p60 subunit A-like 2 1.16223
FHIT fragile histidine triad 1.16177
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 1.15855
SKOR2 SKI family transcriptional corepressor 2 1.14999
PIAS2 protein inhibitor of activated STAT, 2 1.1016
RXRG retinoid X receptor, gamma 1.09906
SCAMP2 secretory carrier membrane protein 2 1.09639
CLNK cytokine-dependent hematopoietic cell linker 1.09365
KIAA1755 KIAA1755 1.09054
PAPLN papilin, proteoglycan-like sulfated glycoprotein 1.0804
SGPP2 sphingosine-1-phosphate phosphatase 2 1.07407
RAVER1 ribonucleoprotein, PTB-binding 1 1.06976
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 1.05869
GRM7 glutamate receptor, metabotropic 7 1.05869
MPI mannose phosphate isomerase 1.05478
FAM219B family with sequence similarity 219, member B 1.0464
ULK3 unc-51 like kinase 3 1.04384
ITK IL2-inducible T-cell kinase 1.04365
SCN1A sodium channel, voltage gated, type I alpha subunit 1.03818
FARSB phenylalanyl-tRNA synthetase, beta subunit 1.03428
TNNT3 troponin T type 3 (skeletal, fast) 1.03114
ANKRD44 ankyrin repeat domain 44 1.02638
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2 1.01883
COX5A cytochrome c oxidase subunit Va 1.01692
FUNDC1 FUN14 domain containing 1 1.01103
SCN5A sodium channel, voltage gated, type V alpha subunit 1.00989
GRM5 glutamate receptor, metabotropic 5 1.00662
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 1.00187
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2) 1.00059
IER3IP1 immediate early response 3 interacting protein 1 1.00059
LMAN1L lectin, mannose-binding, 1 like 0.99698
ARL5B ADP-ribosylation factor-like 5B 0.995928
CRNKL1 crooked neck pre-mRNA splicing factor 1 0.990273
TNRC6C trinucleotide repeat containing 6C 0.989326
CCDC3 coiled-coil domain containing 3 0.986567
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.98077
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.979804
CCSER1 coiled-coil serine-rich protein 1 0.979804
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.977911
LHX6 LIM homeobox 6 0.972231
ECE1 endothelin converting enzyme 1 0.966979
GRIK2 glutamate receptor, ionotropic, kainate 2 0.956975
ARSA arylsulfatase A 0.955595
GRK5 G protein-coupled receptor kinase 5 0.942765
ERBB4 erb-b2 receptor tyrosine kinase 4 0.942765
FLG-AS1 FLG antisense RNA 1 0.942765
CRTAC1 cartilage acidic protein 1 0.93785
FERMT1 fermitin family member 1 0.928309
ASIC2 acid sensing (proton gated) ion channel 2 0.924776
SMOC1 SPARC related modular calcium binding 1 0.923916
KIAA0319 KIAA0319 0.923916
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.919744
NXN nucleoredoxin 0.919136
PSAT1 phosphoserine aminotransferase 1 0.917734
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.917734
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 0.91315
MTCL1 microtubule crosslinking factor 1 0.911691
NOS1 nitric oxide synthase 1 (neuronal) 0.911691
WWOX WW domain containing oxidoreductase 0.909045
KIRREL kin of IRRE like (Drosophila) 0.908445
KIAA1549 KIAA1549 0.899912
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.899731
ATP6AP1L ATPase, H+ transporting, lysosomal accessory protein 1-like 0.898656
BCAS3 breast carcinoma amplified sequence 3 0.898124
DCC DCC netrin 1 receptor 0.897595
RIPK2 receptor-interacting serine-threonine kinase 2 0.894655
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.889642
DCDC2 doublecortin domain containing 2 0.889642
MOGAT1 monoacylglycerol O-acyltransferase 1 0.889297
PTPRD protein tyrosine phosphatase, receptor type, D 0.887424
NME8 NME/NM23 family member 8 0.886585
SYNDIG1 synapse differentiation inducing 1 0.886085
RAD18 RAD18 E3 ubiquitin protein ligase 0.882984
AKAP5 A kinase (PRKA) anchor protein 5 0.882026
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.880922
CFAP61 cilia and flagella associated protein 61 0.876787
CRTC3 CREB regulated transcription coactivator 3 0.873556
FBP1 fructose-1,6-bisphosphatase 1 0.871984
SHROOM3 shroom family member 3 0.870998
REPIN1 replication initiator 1 0.865044
RPA1 replication protein A1, 70kDa 0.864263
MCTP1 multiple C2 domains, transmembrane 1 0.862948
RASGEF1C RasGEF domain family, member 1C 0.862948
CDH13 cadherin 13 0.857878
DENND1A DENN/MADD domain containing 1A 0.855449
NRXN1 neurexin 1 0.855449
CLOCK clock circadian regulator 0.854024
ZFAND2A zinc finger, AN1-type domain 2A 0.852276
KIAA0825 KIAA0825 0.850788
MMRN1 multimerin 1 0.850223
AASS aminoadipate-semialdehyde synthase 0.847125
FAM53B family with sequence similarity 53, member B 0.8468
THUMPD2 THUMP domain containing 2 0.845831
LOC100507002 uncharacterized LOC100507002 0.843198
RIMS1 regulating synaptic membrane exocytosis 1 0.836232
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.836232
CDH23 cadherin-related 23 0.834343
PITPNB phosphatidylinositol transfer protein, beta 0.834343
CSK c-src tyrosine kinase 0.828053
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.825497
LAMB1 laminin, beta 1 0.825497
ADGRB3 adhesion G protein-coupled receptor B3 0.823837
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.81905
CNTN4 contactin 4 0.818279
CYB5A cytochrome b5 type A (microsomal) 0.817516
FRS2 fibroblast growth factor receptor substrate 2 0.817516
CLYBL citrate lyase beta like 0.817516
LOC284395 uncharacterized LOC284395 0.815267
GLI1 GLI family zinc finger 1 0.809986
FBN3 fibrillin 3 0.809986
CD163L1 CD163 molecule-like 1 0.809257
LRRC8B leucine rich repeat containing 8 family, member B 0.805703
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.802966
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.802966
CEP112 centrosomal protein 112kDa 0.802966
CEP85L centrosomal protein 85kDa-like 0.802296
MRPS18C mitochondrial ribosomal protein S18C 0.799025
CTBP2 C-terminal binding protein 2 0.797753
PDCL2 phosducin-like 2 0.7965
SMAD9 SMAD family member 9 0.7965
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.790435
CNTNAP4 contactin associated protein-like 4 0.789787
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.78662
LOC100132891 0.786
ZNF423 zinc finger protein 423 0.784165
ZFPM2 zinc finger protein, FOG family member 2 0.783563
BFSP2 beaded filament structural protein 2, phakinin 0.781192
NT5DC1 5'-nucleotidase domain containing 1 0.777754
MCOLN2 mucolipin 2 0.776085
TENM2 teneurin transmembrane protein 2 0.776085
RSRC1 arginine/serine-rich coiled-coil 1 0.772842
ERCC6L2 excision repair cross-complementation group 6-like 2 0.772842
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.772313
CHD2 chromodomain helicase DNA binding protein 2 0.767696
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.764625
CDYL2 chromodomain protein, Y-like 2 0.763536
ARHGAP22 Rho GTPase activating protein 22 0.762459
ANO4 anoctamin 4 0.757765
ZNF185 zinc finger protein 185 (LIM domain) 0.757258
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.756753
ACBD6 acyl-CoA binding domain containing 6 0.755257
TMEM165 transmembrane protein 165 0.753299
FAF1 Fas (TNFRSF6) associated factor 1 0.753299
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.752335
KEL Kell blood group, metallo-endopeptidase 0.752335
GIPC2 GIPC PDZ domain containing family, member 2 0.750909
CLSTN2 calsyntenin 2 0.750909
COL13A1 collagen, type XIII, alpha 1 0.744097
GFRA1 GDNF family receptor alpha 1 0.743226
FGF14 fibroblast growth factor 14 0.742364
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.739411
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.738997
LOC284080 uncharacterized LOC284080 0.735423
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.734535
EIF4E3 eukaryotic translation initiation factor 4E family member 3 0.734535
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.734535
SLC35F1 solute carrier family 35, member F1 0.731489
ITGA1 integrin, alpha 1 0.731062
DOCK4 dedicator of cytokinesis 4 0.730636
FAM160A1 family with sequence similarity 160, member A1 0.730213
EML6 echinoderm microtubule associated protein like 6 0.729791
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.728954
DCLK1 doublecortin-like kinase 1 0.7273
COL19A1 collagen, type XIX, alpha 1 0.724077
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.723681
PDE7A phosphodiesterase 7A 0.720577
KIAA0930 KIAA0930 0.720196
OFCC1 orofacial cleft 1 candidate 1 0.716836
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.71647
LRP2 low density lipoprotein receptor-related protein 2 0.71502
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.714661
CNTNAP2 contactin associated protein-like 2 0.710116
RYR2 ryanodine receptor 2 (cardiac) 0.707523
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.707154
OPCML opioid binding protein/cell adhesion molecule-like 0.706786
MTFR1 mitochondrial fission regulator 1 0.706055
CAGE1 cancer antigen 1 0.703894
KRT15 keratin 15, type I 0.703894
KRT19 keratin 19, type I 0.700393
SNW1 SNW domain containing 1 0.700393
AGR2 anterior gradient 2 0.700393
PCNA proliferating cell nuclear antigen 0.697013
DAPK1 death-associated protein kinase 1 0.697013
ICOS inducible T-cell co-stimulator 0.694714
MIR31HG MIR31 host gene 0.693745
PACS1 phosphofurin acidic cluster sorting protein 1 0.690896
RYR3 ryanodine receptor 3 0.690584
IL34 interleukin 34 0.687523
ARL15 ADP-ribosylation factor-like 15 0.685142
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.681679
LOC100506023 uncharacterized LOC100506023 0.681679
MACROD1 MACRO domain containing 1 0.678743
ARMC1 armadillo repeat containing 1 0.678131
WDR64 WD repeat domain 64 0.675718
ZRANB3 zinc finger, RAN-binding domain containing 3 0.674532
TMEM117 transmembrane protein 117 0.673652
MOG myelin oligodendrocyte glycoprotein 0.672779
DNM2 dynamin 2 0.672779
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.667145
SNAP25 synaptosomal-associated protein, 25kDa 0.661809
C18ORF63 chromosome 18 open reading frame 63 0.661291
PPP1R36 protein phosphatase 1, regulatory subunit 36 0.661032
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.658991
CCBE1 collagen and calcium binding EGF domains 1 0.658236
GLYATL3 glycine-N-acyltransferase-like 3 0.656743
CSMD1 CUB and Sushi multiple domains 1 0.656743
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.654304
DNHD1 dynein heavy chain domain 1 0.652631
CELF2 CUGBP, Elav-like family member 2 0.651923
MAN1B1 mannosidase, alpha, class 1B, member 1 0.650987
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.649599
ABLIM1 actin binding LIM protein 1 0.648884
BSN bassoon presynaptic cytomatrix protein 0.646367
ASXL1 additional sex combs like transcriptional regulator 1 0.642222
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.640092
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.639858
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.637318
ENAH enabled homolog (Drosophila) 0.635958
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.635284
PRR5L proline rich 5 like 0.633071
MSRA methionine sulfoxide reductase A 0.630903
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.630049
SNX29 sorting nexin 29 0.629625
LINGO2 leucine rich repeat and Ig domain containing 2 0.626701
PLIN3 perilipin 3 0.626701
RASEF RAS and EF-hand domain containing 0.624663
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.624663
RABL6 RAB, member RAS oncogene family-like 6 0.624663
RHBDD3 rhomboid domain containing 3 0.624663
SV2C synaptic vesicle glycoprotein 2C 0.624663
MIR99AHG mir-99a-let-7c cluster host gene 0.62426
DMRT3 doublesex and mab-3 related transcription factor 3 0.622665
NWD2 NACHT and WD repeat domain containing 2 0.622073
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.62168
THSD7B thrombospondin, type I, domain containing 7B 0.620705
VANGL1 VANGL planar cell polarity protein 1 0.620705
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.620705
TSPAN2 tetraspanin 2 0.618783
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.617835
ARHGAP8 Rho GTPase activating protein 8 0.616892
CCDC148 coiled-coil domain containing 148 0.614969
KCNIP1 Kv channel interacting protein 1 0.614969
CAPRIN1 cell cycle associated protein 1 0.614969
MKL2 MKL/myocardin-like 2 0.613082
MCTP2 multiple C2 domains, transmembrane 2 0.611229
LINC00299 long intergenic non-protein coding RNA 299 0.611229
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.610497
FIG4 FIG4 phosphoinositide 5-phosphatase 0.609408
RAB38 RAB38, member RAS oncogene family 0.609408
BMP5 bone morphogenetic protein 5 0.60762
ALOX5 arachidonate 5-lipoxygenase 0.606737
COL5A1 collagen, type V, alpha 1 0.605862
PRKD3 protein kinase D3 0.604135
LCT lactase 0.604135
NAT10 N-acetyltransferase 10 (GCN5-related) 0.604135
BPIFB2 BPI fold containing family B, member 2 0.603112
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.602436
SPEF2 sperm flagellar 2 0.601932
DGKG diacylglycerol kinase, gamma 90kDa 0.601264
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 0.600931
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.600766
DMRT1 doublesex and mab-3 related transcription factor 1 0.599122
TSHZ2 teashirt zinc finger homeobox 2 0.598635
BDNF-AS BDNF antisense RNA 0.598311
NPAS3 neuronal PAS domain protein 3 0.597506
IFI27L2 interferon, alpha-inducible protein 27-like 2 0.597026
EFCAB10 EF-hand calcium binding domain 10 0.594349
SHOX2 short stature homeobox 2 0.593884
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.59296
AFAP1 actin filament associated protein 1 0.59296
VSIG10 V-set and immunoglobulin domain containing 10 0.591289
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.591289
RGS11 regulator of G-protein signaling 11 0.588907
ZNF229 zinc finger protein 229 0.586438
PINK1 PTEN induced putative kinase 1 0.585507
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.585507
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 0.585507
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.584766
KCTD18 potassium channel tetramerization domain containing 18 0.583422
SGMS1 sphingomyelin synthase 1 0.583059
TARSL2 threonyl-tRNA synthetase-like 2 0.583059
AGBL4 ATP/GTP binding protein-like 4 0.581861
LHFPL2 lipoma HMGIC fusion partner-like 2 0.581861
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.581268
FASTKD2 FAST kinase domains 2 0.579512
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.579165
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.57836
ANGPT4 angiopoietin 4 0.57836
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.577224
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.576774
OC90 otoconin 90 0.574995
MED31 mediator complex subunit 31 0.573902
ANGPT1 angiopoietin 1 0.573361
ST18 suppression of tumorigenicity 18, zinc finger 0.572823
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.572823
DRD1 dopamine receptor D1 0.572823
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0.522136
FAM110B family with sequence similarity 110, member B 0.522136
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.522136
SERINC5 serine incorporator 5 0.454179