personality disorder Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A disease of mental health that involve long-term patterns of thoughts and behaviors that cause serious problems with relationships and work. (Human Disease Ontology, DOID_1510)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1510
Similar Terms
Downloads & Tools

Genes

306 genes associated with the disease personality disorder in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
PLCE1 phospholipase C, epsilon 1 1.35834
KATNAL2 katanin p60 subunit A-like 2 1.32653
FHIT fragile histidine triad 1.32598
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 1.32218
SKOR2 SKI family transcriptional corepressor 2 1.31262
PIAS2 protein inhibitor of activated STAT, 2 1.25746
RXRG retinoid X receptor, gamma 1.25477
SCAMP2 secretory carrier membrane protein 2 1.25198
CLNK cytokine-dependent hematopoietic cell linker 1.24871
KIAA1755 KIAA1755 1.24497
PAPLN papilin, proteoglycan-like sulfated glycoprotein 1.234
SGPP2 sphingosine-1-phosphate phosphatase 2 1.22689
RAVER1 ribonucleoprotein, PTB-binding 1 1.22257
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 1.21019
GRM7 glutamate receptor, metabotropic 7 1.21019
MPI mannose phosphate isomerase 1.20608
FAM219B family with sequence similarity 219, member B 1.19692
ULK3 unc-51 like kinase 3 1.19408
NRXN1 neurexin 1 1.19386
ITK IL2-inducible T-cell kinase 1.19386
SCN1A sodium channel, voltage gated, type I alpha subunit 1.18762
FARSB phenylalanyl-tRNA synthetase, beta subunit 1.18343
TNNT3 troponin T type 3 (skeletal, fast) 1.18008
ANKRD44 ankyrin repeat domain 44 1.17489
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2 1.1662
COX5A cytochrome c oxidase subunit Va 1.16393
FUNDC1 FUN14 domain containing 1 1.1576
SCN5A sodium channel, voltage gated, type V alpha subunit 1.15641
GRM5 glutamate receptor, metabotropic 5 1.15242
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 1.14629
IER3IP1 immediate early response 3 interacting protein 1 1.14463
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2) 1.14463
MSRB3 methionine sulfoxide reductase B3 1.14463
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 1.14463
LMAN1L lectin, mannose-binding, 1 like 1.14065
ARL5B ADP-ribosylation factor-like 5B 1.1395
CRNKL1 crooked neck pre-mRNA splicing factor 1 1.13288
TNRC6C trinucleotide repeat containing 6C 1.13167
CCDC3 coiled-coil domain containing 3 1.12815
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 1.12121
CCSER1 coiled-coil serine-rich protein 1 1.12017
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 1.12017
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.11813
LHX6 LIM homeobox 6 1.1116
ECE1 endothelin converting enzyme 1 1.10487
GRIK2 glutamate receptor, ionotropic, kainate 2 1.09343
ARSA arylsulfatase A 1.09196
ERBB4 erb-b2 receptor tyrosine kinase 4 1.07599
FLG-AS1 FLG antisense RNA 1 1.07599
GRK5 G protein-coupled receptor kinase 5 1.07599
CRTAC1 cartilage acidic protein 1 1.07024
FERMT1 fermitin family member 1 1.05943
ASIC2 acid sensing (proton gated) ion channel 2 1.0549
KIAA0319 KIAA0319 1.0538
SMOC1 SPARC related modular calcium binding 1 1.0538
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 1.04846
PTPRD protein tyrosine phosphatase, receptor type, D 1.04846
SLA Src-like-adaptor 1.04846
CADM2 cell adhesion molecule 2 1.04846
NXN nucleoredoxin 1.04769
PSAT1 phosphoserine aminotransferase 1 1.0459
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.0459
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.04048
NOS1 nitric oxide synthase 1 (neuronal) 1.03882
MTCL1 microtubule crosslinking factor 1 1.03882
WWOX WW domain containing oxidoreductase 1.0358
KIRREL kin of IRRE like (Drosophila) 1.03512
KIAA1549 KIAA1549 1.02476
CASC15 cancer susceptibility candidate 15 (non-protein coding) 1.02453
ATP6AP1L ATPase, H+ transporting, lysosomal accessory protein 1-like 1.02317
BCAS3 breast carcinoma amplified sequence 3 1.02249
DCC DCC netrin 1 receptor 1.02182
RIPK2 receptor-interacting serine-threonine kinase 2 1.0181
DCDC2 doublecortin domain containing 2 1.01185
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 1.01185
MOGAT1 monoacylglycerol O-acyltransferase 1 1.01145
NME8 NME/NM23 family member 8 1.00827
SYNDIG1 synapse differentiation inducing 1 1.00769
RAD18 RAD18 E3 ubiquitin protein ligase 1.00407
AKAP5 A kinase (PRKA) anchor protein 5 1.00295
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 1.00166
CFAP61 cilia and flagella associated protein 61 0.996743
CRTC3 CREB regulated transcription coactivator 3 0.992818
FBP1 fructose-1,6-bisphosphatase 1 0.990911
SHROOM3 shroom family member 3 0.989716
REPIN1 replication initiator 1 0.98251
RPA1 replication protein A1, 70kDa 0.981566
MCTP1 multiple C2 domains, transmembrane 1 0.980012
RASGEF1C RasGEF domain family, member 1C 0.980012
CDH13 cadherin 13 0.97403
DENND1A DENN/MADD domain containing 1A 0.971169
FBN2 fibrillin 2 0.971169
CLOCK clock circadian regulator 0.969492
ZFAND2A zinc finger, AN1-type domain 2A 0.967464
KIAA0825 KIAA0825 0.965779
MMRN1 multimerin 1 0.96514
AASS aminoadipate-semialdehyde synthase 0.961634
FAM53B family with sequence similarity 53, member B 0.961266
THUMPD2 THUMP domain containing 2 0.960171
LOC100507002 uncharacterized LOC100507002 0.957195
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.949336
RIMS1 regulating synaptic membrane exocytosis 1 0.949336
PITPNB phosphatidylinositol transfer protein, beta 0.947208
CDH23 cadherin-related 23 0.947208
CSK c-src tyrosine kinase 0.940135
LAMB1 laminin, beta 1 0.937304
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.937304
ADGRB3 adhesion G protein-coupled receptor B3 0.935465
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.930169
CNTN4 contactin 4 0.929316
FRS2 fibroblast growth factor receptor substrate 2 0.928472
CYB5A cytochrome b5 type A (microsomal) 0.928472
CLYBL citrate lyase beta like 0.928472
LOC284395 uncharacterized LOC284395 0.925987
GLI1 GLI family zinc finger 1 0.920453
FBN3 fibrillin 3 0.920453
CD163L1 CD163 molecule-like 1 0.91969
LRRC8B leucine rich repeat containing 8 family, member B 0.915976
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.912987
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.912987
CEP112 centrosomal protein 112kDa 0.912987
CEP85L centrosomal protein 85kDa-like 0.912226
MRPS18C mitochondrial ribosomal protein S18C 0.908515
CTBP2 C-terminal binding protein 2 0.907073
SMAD9 SMAD family member 9 0.905653
PDCL2 phosducin-like 2 0.905653
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.898875
CNTNAP4 contactin associated protein-like 4 0.898225
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.895044
LOC100132891 0.894421
ZNF423 zinc finger protein 423 0.892579
ZFPM2 zinc finger protein, FOG family member 2 0.891974
BFSP2 beaded filament structural protein 2, phakinin 0.889594
NT5DC1 5'-nucleotidase domain containing 1 0.885884
MCOLN2 mucolipin 2 0.884
TENM2 teneurin transmembrane protein 2 0.884
RSRC1 arginine/serine-rich coiled-coil 1 0.88034
ERCC6L2 excision repair cross-complementation group 6-like 2 0.88034
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.879744
CHD2 chromodomain helicase DNA binding protein 2 0.874542
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.871229
CDYL2 chromodomain protein, Y-like 2 0.87015
ARHGAP22 Rho GTPase activating protein 22 0.869084
ANO4 anoctamin 4 0.864435
ZNF185 zinc finger protein 185 (LIM domain) 0.863933
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.863433
ACBD6 acyl-CoA binding domain containing 6 0.861951
TMEM165 transmembrane protein 165 0.859982
FAF1 Fas (TNFRSF6) associated factor 1 0.859982
KEL Kell blood group, metallo-endopeptidase 0.858922
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.858922
GIPC2 GIPC PDZ domain containing family, member 2 0.857354
CLSTN2 calsyntenin 2 0.857354
COL13A1 collagen, type XIII, alpha 1 0.849872
GFRA1 GDNF family receptor alpha 1 0.848917
FGF14 fibroblast growth factor 14 0.847971
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.844732
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.844278
LOC284080 uncharacterized LOC284080 0.840723
EIF4E3 eukaryotic translation initiation factor 4E family member 3 0.839855
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.839855
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.839855
SLC35F1 solute carrier family 35, member F1 0.836877
ITGA1 integrin, alpha 1 0.836459
DOCK4 dedicator of cytokinesis 4 0.836043
FAM160A1 family with sequence similarity 160, member A1 0.835629
EML6 echinoderm microtubule associated protein like 6 0.835216
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.834397
DCLK1 doublecortin-like kinase 1 0.832779
COL19A1 collagen, type XIX, alpha 1 0.829434
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.829001
PDE7A phosphodiesterase 7A 0.825607
KIAA0930 KIAA0930 0.82519
OFCC1 orofacial cleft 1 candidate 1 0.821519
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.821119
LRP2 low density lipoprotein receptor-related protein 2 0.819536
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.819144
CNTNAP2 contactin associated protein-like 2 0.814185
RYR2 ryanodine receptor 2 (cardiac) 0.811614
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.811252
OPCML opioid binding protein/cell adhesion molecule-like 0.810892
MTFR1 mitochondrial fission regulator 1 0.810175
CAGE1 cancer antigen 1 0.808055
KRT15 keratin 15, type I 0.808055
SNW1 SNW domain containing 1 0.804621
AGR2 anterior gradient 2 0.804621
KRT19 keratin 19, type I 0.804621
PCNA proliferating cell nuclear antigen 0.801304
DAPK1 death-associated protein kinase 1 0.801304
ICOS inducible T-cell co-stimulator 0.798811
MIR31HG MIR31 host gene 0.79774
PACS1 phosphofurin acidic cluster sorting protein 1 0.794591
RYR3 ryanodine receptor 3 0.794247
IL34 interleukin 34 0.790866
ARL15 ADP-ribosylation factor-like 15 0.788239
LOC100506023 uncharacterized LOC100506023 0.78442
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.78442
MACROD1 MACRO domain containing 1 0.781342
ARMC1 armadillo repeat containing 1 0.780738
WDR64 WD repeat domain 64 0.778355
ZRANB3 zinc finger, RAN-binding domain containing 3 0.777184
TMEM117 transmembrane protein 117 0.776314
DNM2 dynamin 2 0.775452
MOG myelin oligodendrocyte glycoprotein 0.775452
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.769887
SNAP25 synaptosomal-associated protein, 25kDa 0.764084
C18ORF63 chromosome 18 open reading frame 63 0.763511
PPP1R36 protein phosphatase 1, regulatory subunit 36 0.763226
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.760971
CCBE1 collagen and calcium binding EGF domains 1 0.760137
GLYATL3 glycine-N-acyltransferase-like 3 0.758489
CSMD1 CUB and Sushi multiple domains 1 0.758489
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.755798
DNHD1 dynein heavy chain domain 1 0.753954
CELF2 CUGBP, Elav-like family member 2 0.753174
MAN1B1 mannosidase, alpha, class 1B, member 1 0.752142
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.750612
ABLIM1 actin binding LIM protein 1 0.749856
BSN bassoon presynaptic cytomatrix protein 0.747373
ASXL1 additional sex combs like transcriptional regulator 1 0.743283
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.741181
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.74095
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.738443
ENAH enabled homolog (Drosophila) 0.737101
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.736436
PRR5L proline rich 5 like 0.734059
MSRA methionine sulfoxide reductase A 0.731685
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.73075
SNX29 sorting nexin 29 0.730285
PLIN3 perilipin 3 0.727087
LINGO2 leucine rich repeat and Ig domain containing 2 0.727087
RABL6 RAB, member RAS oncogene family-like 6 0.724858
RHBDD3 rhomboid domain containing 3 0.724858
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.724858
RASEF RAS and EF-hand domain containing 0.724858
SV2C synaptic vesicle glycoprotein 2C 0.724858
MIR99AHG mir-99a-let-7c cluster host gene 0.724417
DMRT3 doublesex and mab-3 related transcription factor 3 0.722673
NWD2 NACHT and WD repeat domain containing 2 0.722026
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 0.721597
THSD7B thrombospondin, type I, domain containing 7B 0.720532
VANGL1 VANGL planar cell polarity protein 1 0.720532
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.720532
TSPAN2 tetraspanin 2 0.718432
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.717397
ARHGAP8 Rho GTPase activating protein 8 0.716372
CCDC148 coiled-coil domain containing 148 0.714351
CAPRIN1 cell cycle associated protein 1 0.714351
KCNIP1 Kv channel interacting protein 1 0.714351
MKL2 MKL/myocardin-like 2 0.712368
LINC00299 long intergenic non-protein coding RNA 299 0.71042
MCTP2 multiple C2 domains, transmembrane 2 0.71042
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.709651
RAB38 RAB38, member RAS oncogene family 0.708508
FIG4 FIG4 phosphoinositide 5-phosphatase 0.708508
BMP5 bone morphogenetic protein 5 0.70663
ALOX5 arachidonate 5-lipoxygenase 0.705703
COL5A1 collagen, type V, alpha 1 0.704784
LCT lactase 0.70297
PRKD3 protein kinase D3 0.70297
NAT10 N-acetyltransferase 10 (GCN5-related) 0.70297
BPIFB2 BPI fold containing family B, member 2 0.701897
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.701191
SPEF2 sperm flagellar 2 0.700665
DGKG diacylglycerol kinase, gamma 90kDa 0.699967
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 0.699619
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.699446
DMRT1 doublesex and mab-3 related transcription factor 1 0.69773
TSHZ2 teashirt zinc finger homeobox 2 0.697221
BDNF-AS BDNF antisense RNA 0.696883
NPAS3 neuronal PAS domain protein 3 0.696042
IFI27L2 interferon, alpha-inducible protein 27-like 2 0.695541
EFCAB10 EF-hand calcium binding domain 10 0.692747
SHOX2 short stature homeobox 2 0.692261
AFAP1 actin filament associated protein 1 0.691297
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.691297
VSIG10 V-set and immunoglobulin domain containing 10 0.689554
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.689554
RGS11 regulator of G-protein signaling 11 0.687069
ZNF229 zinc finger protein 229 0.684494
PINK1 PTEN induced putative kinase 1 0.683452
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.683452
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 0.683452
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.682568
KCTD18 potassium channel tetramerization domain containing 18 0.680967
SGMS1 sphingomyelin synthase 1 0.680534
TARSL2 threonyl-tRNA synthetase-like 2 0.680534
LHFPL2 lipoma HMGIC fusion partner-like 2 0.679107
AGBL4 ATP/GTP binding protein-like 4 0.679107
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.6784
FASTKD2 FAST kinase domains 2 0.67631
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.675898
ANGPT4 angiopoietin 4 0.674941
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.674941
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.67359
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.673055
OC90 otoconin 90 0.670943
MED31 mediator complex subunit 31 0.669849
ANGPT1 angiopoietin 1 0.669341
ST18 suppression of tumorigenicity 18, zinc finger 0.668836
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.668836
DRD1 dopamine receptor D1 0.668836
FAM110B family with sequence similarity 110, member B 0.615118
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0.615118
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.615118
SERINC5 serine incorporator 5 0.532436