peripheral nervous system disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A nervous system disease that affects the peripheral nervous system. (Human Disease Ontology, DOID_574)
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Genes

681 genes co-occuring with the disease peripheral nervous system disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TTR transthyretin 3.33243
MAG myelin associated glycoprotein 2.37886
PNPLA6 patatin-like phospholipase domain containing 6 2.09948
PMP22 peripheral myelin protein 22 1.99179
CST7 cystatin F (leukocystatin) 1.89592
B2M beta-2-microglobulin 1.7496
MPZ myelin protein zero 1.73277
INS insulin 1.70087
MBTPS2 membrane-bound transcription factor peptidase, site 2 1.66195
SEPT9 septin 9 1.49569
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.46363
GSN gelsolin 1.42674
TAC1 tachykinin, precursor 1 1.42586
CALCA calcitonin-related polypeptide alpha 1.4057
COL6A1 collagen, type VI, alpha 1 1.39083
GJB1 gap junction protein, beta 1, 32kDa 1.38996
PPY pancreatic polypeptide 1.38472
APCS amyloid P component, serum 1.35333
CD79A CD79a molecule, immunoglobulin-associated alpha 1.35245
ALB albumin 1.3494
NGF nerve growth factor (beta polypeptide) 1.31974
NPS neuropeptide S 1.2813
ABHD12 abhydrolase domain containing 12 1.23429
FKBP1A FK506 binding protein 1A, 12kDa 1.13459
MAP6D1 MAP6 domain containing 1 1.11519
GAN gigaxonin 1.08034
EGOT eosinophil granule ontogeny transcript (non-protein coding) 1.04966
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 1.04335
CES1P1 carboxylesterase 1 pseudogene 1 1.04293
CD4 CD4 molecule 1.04125
PORCN porcupine homolog (Drosophila) 1.00625
GCG glucagon 1.00203
NFASC neurofascin 0.994017
EGR2 early growth response 2 0.985585
TNF tumor necrosis factor 0.978426
NOTCH1 notch 1 0.966663
LSR lipolysis stimulated lipoprotein receptor 0.965405
HBA2 hemoglobin, alpha 2 0.955779
MFN2 mitofusin 2 0.947435
DPYSL5 dihydropyrimidinase-like 5 0.945354
HBA1 hemoglobin, alpha 1 0.94078
CAMP cathelicidin antimicrobial peptide 0.939119
MTMR2 myotubularin related protein 2 0.925865
NPY neuropeptide Y 0.902389
ACHE acetylcholinesterase (Yt blood group) 0.882701
IFNB1 interferon, beta 1, fibroblast 0.84544
GDAP1 ganglioside induced differentiation associated protein 1 0.845031
IL1B interleukin 1, beta 0.835607
SH2D2A SH2 domain containing 2A 0.812232
HMGA2 high mobility group AT-hook 2 0.811411
PSD2 pleckstrin and Sec7 domain containing 2 0.811001
SKAP2 src kinase associated phosphoprotein 2 0.806898
PALM3 paralemmin 3 0.805257
SEPT5 septin 5 0.795411
BMP2 bone morphogenetic protein 2 0.795002
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.795002
GLDN gliomedin 0.774932
MBP myelin basic protein 0.773705
MLN motilin 0.770435
NTF3 neurotrophin 3 0.763086
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.746391
SST somatostatin 0.74436
POMC proopiomelanocortin 0.730976
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.729762
IL6 interleukin 6 0.723694
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.723694
FIG4 FIG4 phosphoinositide 5-phosphatase 0.722482
SKOR1 SKI family transcriptional corepressor 1 0.722077
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.709572
CD1E CD1e molecule 0.705144
PRX periaxin 0.700722
CFAP126 cilia and flagella associated protein 126 0.695905
CRP C-reactive protein, pentraxin-related 0.691896
LYZ lysozyme 0.685891
ACE angiotensin I converting enzyme 0.677903
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.675112
POLG polymerase (DNA directed), gamma 0.66755
WRB tryptophan rich basic protein 0.661594
NDRG1 N-myc downstream regulated 1 0.6608
CTSA cathepsin A 0.660404
SACS sacsin molecular chaperone 0.660404
IGF1 insulin-like growth factor 1 (somatomedin C) 0.658422
CCK cholecystokinin 0.653276
CNTN2 contactin 2 (axonal) 0.653276
CBR4 carbonyl reductase 4 0.637102
BTBD9 BTB (POZ) domain containing 9 0.629635
CD6 CD6 molecule 0.626495
HSF4 heat shock transcription factor 4 0.625319
PSD4 pleckstrin and Sec7 domain containing 4 0.624927
KLK8 kallikrein-related peptidase 8 0.622575
PSD3 pleckstrin and Sec7 domain containing 3 0.619442
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 0.619442
IVD isovaleryl-CoA dehydrogenase 0.614747
DNAH17 dynein, axonemal, heavy chain 17 0.613183
EDC4 enhancer of mRNA decapping 4 0.608494
REN renin 0.60303
AVP arginine vasopressin 0.59991
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.589779
PHYH phytanoyl-CoA 2-hydroxylase 0.58005
TACR1 tachykinin receptor 1 0.571884
RIMBP2 RIMS binding protein 2 0.55945
ALPPL2 alkaline phosphatase, placental-like 2 0.549747
VEGFA vascular endothelial growth factor A 0.549747
ALPP alkaline phosphatase, placental 0.549359
ALPL alkaline phosphatase, liver/bone/kidney 0.548583
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.547419
REXO2 RNA exonuclease 2 0.540829
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.535022
APOA1 apolipoprotein A-I 0.534248
IFT122 intraflagellar transport 122 0.533475
AVPR2 arginine vasopressin receptor 2 0.533088
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.532701
ATXN3 ataxin 3 0.530381
LCK LCK proto-oncogene, Src family tyrosine kinase 0.528835
GPC3 glypican 3 0.524974
F8 coagulation factor VIII, procoagulant component 0.51611
PTH parathyroid hormone 0.515725
NF1 neurofibromin 1 0.514956
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.513033
GIP gastric inhibitory polypeptide 0.510344
SPG11 spastic paraplegia 11 (autosomal recessive) 0.502675
PRUNE prune exopolyphosphatase 0.499997
KIN Kin17 DNA and RNA binding protein 0.491978
C10ORF2 chromosome 10 open reading frame 2 0.491978
MAP2K5 mitogen-activated protein kinase kinase 5 0.490454
LITAF lipopolysaccharide-induced TNF factor 0.490454
IGLJ3 immunoglobulin lambda joining 3 0.478289
CD68 CD68 molecule 0.476772
IFNA1 interferon, alpha 1 0.471468
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.470711
ALLC allantoicase 0.468819
PSD pleckstrin and Sec7 domain containing 0.46655
BGLAP bone gamma-carboxyglutamate (gla) protein 0.465794
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 0.465038
KIF5A kinesin family member 5A 0.463527
DHH desert hedgehog 0.463149
PARP14 poly (ADP-ribose) polymerase family, member 14 0.462016
SEPT7 septin 7 0.461261
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.460129
AGER advanced glycosylation end product-specific receptor 0.456355
ARSA arylsulfatase A 0.455601
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 0.451454
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.451454
GALC galactosylceramidase 0.448064
BDNF brain-derived neurotrophic factor 0.445805
GAST gastrin 0.445052
PPT1 palmitoyl-protein thioesterase 1 0.444676
CNTNAP1 contactin associated protein 1 0.440914
CTGF connective tissue growth factor 0.440914
IFNA2 interferon, alpha 2 0.43753
BCHE butyrylcholinesterase 0.436778
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 0.435651
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.434524
B3GAT1 beta-1,3-glucuronyltransferase 1 0.433772
ZDHHC23 zinc finger, DHHC-type containing 23 0.433397
OSGIN2 oxidative stress induced growth inhibitor family member 2 0.431894
TYMP thymidine phosphorylase 0.42589
CD86 CD86 molecule 0.425514
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.42214
SAP30BP SAP30 binding protein 0.421016
AMPH amphiphysin 0.418394
ANKLE2 ankyrin repeat and LEM domain containing 2 0.41727
CLDN5 claudin 5 0.415773
HLA-C major histocompatibility complex, class I, C 0.414276
CDK13 cyclin-dependent kinase 13 0.410535
AFG3L2 AFG3-like AAA ATPase 2 0.406798
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.405678
NF2 neurofibromin 2 (merlin) 0.404557
IL1RN interleukin 1 receptor antagonist 0.404557
CNTN3 contactin 3 (plasmacytoma associated) 0.404184
PMP2 peripheral myelin protein 2 0.403438
FRMPD1 FERM and PDZ domain containing 1 0.403064
TH tyrosine hydroxylase 0.403064
GALK2 galactokinase 2 0.397471
LMNA lamin A/C 0.396353
AIF1 allograft inflammatory factor 1 0.394491
ATF3 activating transcription factor 3 0.394118
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.390397
CAPN15 calpain 15 0.388166
BMP2K BMP2 inducible kinase 0.385193
WDFY2 WD repeat and FYVE domain containing 2 0.382966
CLDN11 claudin 11 0.381852
NPPA natriuretic peptide A 0.381481
SETX senataxin 0.377031
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.37629
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.374809
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.372217
DMXL2 Dmx-like 2 0.368149
DPYSL4 dihydropyrimidinase-like 4 0.36704
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.366301
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.364824
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.364824
FA2H fatty acid 2-hydroxylase 0.364454
CNTF ciliary neurotrophic factor 0.364454
CST3 cystatin C 0.364454
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.362978
PRSS21 protease, serine, 21 (testisin) 0.362239
PCSK7 proprotein convertase subtilisin/kexin type 7 0.361502
TTC34 tetratricopeptide repeat domain 34 0.360395
LIN9 lin-9 DREAM MuvB core complex component 0.358183
SBF2 SET binding factor 2 0.355235
NEFL neurofilament, light polypeptide 0.351555
VASN vasorin 0.350084
ICAM1 intercellular adhesion molecule 1 0.350084
CCL2 chemokine (C-C motif) ligand 2 0.349717
CPA5 carboxypeptidase A5 0.344574
CXCL9 chemokine (C-X-C motif) ligand 9 0.34384
LAX1 lymphocyte transmembrane adaptor 1 0.343473
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 0.343473
EDA ectodysplasin A 0.343473
YIPF4 Yip1 domain family, member 4 0.342006
HCRT hypocretin (orexin) neuropeptide precursor 0.342006
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.342006
LARS leucyl-tRNA synthetase 0.33944
MPO myeloperoxidase 0.339073
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.338341
WAPAL wings apart-like homolog (Drosophila) 0.337242
MMP9 matrix metallopeptidase 9 0.330295
IDS iduronate 2-sulfatase 0.32701
AJAP1 adherens junctions associated protein 1 0.324823
INF2 inverted formin, FH2 and WH2 domain containing 0.320454
IAPP islet amyloid polypeptide 0.320454
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 0.319726
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.318999
AMD1 adenosylmethionine decarboxylase 1 0.313189
CCNA2 cyclin A2 0.312464
SEPT14 septin 14 0.311377
SPAST spastin 0.311377
MGAM maltase-glucoamylase 0.307395
PHGDH phosphoglycerate dehydrogenase 0.305587
CHAT choline O-acetyltransferase 0.298371
SOD2 superoxide dismutase 2, mitochondrial 0.296211
KNG1 kininogen 1 0.296211
CXCL10 chemokine (C-X-C motif) ligand 10 0.292975
MLNR motilin receptor 0.291539
PEX7 peroxisomal biogenesis factor 7 0.29118
FOS FBJ murine osteosarcoma viral oncogene homolog 0.28294
GDNF glial cell derived neurotrophic factor 0.282582
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.282582
ZFYVE27 zinc finger, FYVE domain containing 27 0.281153
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.27794
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.275089
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.274376
GGT1 gamma-glutamyltransferase 1 0.272953
GCH1 GTP cyclohydrolase 1 0.270819
APOA2 apolipoprotein A-II 0.270108
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.268332
IL2RA interleukin 2 receptor, alpha 0.265494
NBAS neuroblastoma amplified sequence 0.264077
CD1B CD1b molecule 0.26266
PER1 period circadian clock 1 0.261952
IVL involucrin 0.260538
PYY peptide YY 0.260538
TF transferrin 0.257711
ALAD aminolevulinate dehydratase 0.256299
INPP5J inositol polyphosphate-5-phosphatase J 0.255946
NIN ninein (GSK3B interacting protein) 0.254888
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 0.253127
PIDD1 p53-induced death domain protein 1 0.250663
CPN1 carboxypeptidase N, polypeptide 1 0.250311
LDHC lactate dehydrogenase C 0.243645
CD276 CD276 molecule 0.241895
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.241546
CLEC2A C-type lectin domain family 2, member A 0.241196
C7ORF49 chromosome 7 open reading frame 49 0.240847
CINP cyclin-dependent kinase 2 interacting protein 0.240497
SORD sorbitol dehydrogenase 0.237706
ADRA1A adrenoceptor alpha 1A 0.234573
SIGLEC7 sialic acid binding Ig-like lectin 7 0.232836
ERLIN2 ER lipid raft associated 2 0.230755
CBS cystathionine-beta-synthase 0.230409
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.229024
FTL ferritin, light polypeptide 0.228679
FTH1 ferritin, heavy polypeptide 1 0.228679
NPTX2 neuronal pentraxin II 0.223509
CLIC2 chloride intracellular channel 2 0.222822
TNXB tenascin XB 0.220424
TRIM21 tripartite motif containing 21 0.218034
PARP9 poly (ADP-ribose) polymerase family, member 9 0.218034
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.215653
PLA2G1B phospholipase A2, group IB (pancreas) 0.215653
SOX21 SRY (sex determining region Y)-box 21 0.214975
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.212945
PDLIM2 PDZ and LIM domain 2 (mystique) 0.212608
ENO2 enolase 2 (gamma, neuronal) 0.211597
RICTOR RPTOR independent companion of MTOR, complex 2 0.210589
ACAN aggrecan 0.209918
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.209583
NUMBL numb homolog (Drosophila)-like 0.208914
NPPB natriuretic peptide B 0.207578
VIP vasoactive intestinal peptide 0.205916
PNKP polynucleotide kinase 3'-phosphatase 0.204923
FGF7 fibroblast growth factor 7 0.204593
TNXA tenascin XA (pseudogene) 0.199033
NEFH neurofilament, heavy polypeptide 0.19742
FGD4 FYVE, RhoGEF and PH domain containing 4 0.197099
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.194232
SAA1 serum amyloid A1 0.194232
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.193285
SAA2 serum amyloid A2 0.190786
OMD osteomodulin 0.190786
SEPT11 septin 11 0.189551
CRCP CGRP receptor component 0.188938
GFAP glial fibrillary acidic protein 0.188938
CLEC10A C-type lectin domain family 10, member A 0.187719
AMBP alpha-1-microglobulin/bikunin precursor 0.185016
CCR2 chemokine (C-C motif) receptor 2 0.183541
RTKN rhotekin 0.182957
SSX2B synovial sarcoma, X breakpoint 2B 0.180084
PRDM16 PR domain containing 16 0.179802
IDUA iduronidase, alpha-L- 0.177301
APOA4 apolipoprotein A-IV 0.177029
MRPL49 mitochondrial ribosomal protein L49 0.175411
NRCAM neuronal cell adhesion molecule 0.175146
DNAH8 dynein, axonemal, heavy chain 8 0.173571
IGLL5 immunoglobulin lambda-like polypeptide 5 0.173314
SRPX2 sushi-repeat containing protein, X-linked 2 0.170789
TTC39A tetratricopeptide repeat domain 39A 0.170789
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.169812
TGFB1 transforming growth factor, beta 1 0.16933
RBP4 retinol binding protein 4, plasma 0.169091
AMPD2 adenosine monophosphate deaminase 2 0.167915
EMP3 epithelial membrane protein 3 0.167682
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.165435
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.165001
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.163938
MNT MAX network transcriptional repressor 0.163729
C1QC complement component 1, q subcomponent, C chain 0.161716
CCL3 chemokine (C-C motif) ligand 3 0.161716
SPTA1 spectrin, alpha, erythrocytic 1 0.161523
PRTN3 proteinase 3 0.161139
AMPD1 adenosine monophosphate deaminase 1 0.160761
ZCCHC7 zinc finger, CCHC domain containing 7 0.160574
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.159302
ASGR2 asialoglycoprotein receptor 2 0.159124
MME membrane metallo-endopeptidase 0.158951
HHAT hedgehog acyltransferase 0.158951
HSF1 heat shock transcription factor 1 0.158778
LY96 lymphocyte antigen 96 0.158778
TRH thyrotropin-releasing hormone 0.157929
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.138568
ST5 suppression of tumorigenicity 5 0.13429
TSKU tsukushi, small leucine rich proteoglycan 0.132673
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.131585
CNTN1 contactin 1 0.130895
IPP intracisternal A particle-promoted polypeptide 0.130882
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.129341
ADAM2 ADAM metallopeptidase domain 2 0.128644
SYCP3 synaptonemal complex protein 3 0.128162
PRSS50 protease, serine, 50 0.128084
RPIA ribose 5-phosphate isomerase A 0.127381
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.126898
FOXL2 forkhead box L2 0.12672
SRSF2 serine/arginine-rich splicing factor 2 0.125523
CCR1 chemokine (C-C motif) receptor 1 0.125263
GRM6 glutamate receptor, metabotropic 6 0.125126
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.125104
MBD5 methyl-CpG binding domain protein 5 0.124831
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.124442
BIN3 bridging integrator 3 0.124431
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.123483
CRLF1 cytokine receptor-like factor 1 0.123459
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.123326
CCL23 chemokine (C-C motif) ligand 23 0.123175
IHH indian hedgehog 0.123157
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.123132
SYNM synemin, intermediate filament protein 0.12282
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.122814
UBE2K ubiquitin-conjugating enzyme E2K 0.122671
RRM1 ribonucleotide reductase M1 0.122621
BMP3 bone morphogenetic protein 3 0.122571
THEM4 thioesterase superfamily member 4 0.122074
DLAT dihydrolipoamide S-acetyltransferase 0.121951
INA internexin neuronal intermediate filament protein, alpha 0.121931
SEPT1 septin 1 0.121891
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.121765
FBXW2 F-box and WD repeat domain containing 2 0.121138
GALR2 galanin receptor 2 0.120863
C5 complement component 5 0.12078
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.120093
ZC3H12D zinc finger CCCH-type containing 12D 0.119948
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.119617
AANAT aralkylamine N-acetyltransferase 0.119171
TBX1 T-box 1 0.117676
PGRMC1 progesterone receptor membrane component 1 0.117335
SPAG7 sperm associated antigen 7 0.116682
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.116623
C5ORF38 chromosome 5 open reading frame 38 0.116184
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.115977
GRM4 glutamate receptor, metabotropic 4 0.115597
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.115571
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.115377
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.115323
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.114159
MUSK muscle, skeletal, receptor tyrosine kinase 0.113865
LCAT lecithin-cholesterol acyltransferase 0.113176
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.112872
DCD dermcidin 0.112569
FBXO17 F-box protein 17 0.112325
HAND1 heart and neural crest derivatives expressed 1 0.111421
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.110801
ANKRD11 ankyrin repeat domain 11 0.109928
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.109524
CD27 CD27 molecule 0.109375
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.109152
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.108891
PMF1 polyamine-modulated factor 1 0.108727
SCGB3A1 secretoglobin, family 3A, member 1 0.108716
NRP1 neuropilin 1 0.108672
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.108639
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.108333
ARSB arylsulfatase B 0.108311
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.108278
HTN3 histatin 3 0.108004
MRC1 mannose receptor, C type 1 0.10797
SIK1 salt-inducible kinase 1 0.107104
SELL selectin L 0.107048
MMP3 matrix metallopeptidase 3 0.106934
TK1 thymidine kinase 1, soluble 0.106865
MATK megakaryocyte-associated tyrosine kinase 0.106726
UBIAD1 UbiA prenyltransferase domain containing 1 0.10668
GGT2 gamma-glutamyltransferase 2 0.106645
OCLN occludin 0.106518
IK IK cytokine, down-regulator of HLA II 0.106507
CASC5 cancer susceptibility candidate 5 0.106207
DPT dermatopontin 0.105812
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.105207
WDR20 WD repeat domain 20 0.104598
SAA4 serum amyloid A4, constitutive 0.104525
NMU neuromedin U 0.104246
SCN10A sodium channel, voltage gated, type X alpha subunit 0.104209
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.10399
CNOT2 CCR4-NOT transcription complex, subunit 2 0.103845
ETV3 ets variant 3 0.103363
GALE UDP-galactose-4-epimerase 0.102604
C5AR1 complement component 5a receptor 1 0.102591
NCF1C neutrophil cytosolic factor 1C pseudogene 0.102591
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.101136
SPHK1 sphingosine kinase 1 0.101083
GAL galanin/GMAP prepropeptide 0.100952
SPTB spectrin, beta, erythrocytic 0.100691
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.100469
SHD Src homology 2 domain containing transforming protein D 0.100051
GPR148 G protein-coupled receptor 148 0.099958
NCF1 neutrophil cytosolic factor 1 0.099944
ECE1 endothelin converting enzyme 1 0.099704
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.099089
ADAR adenosine deaminase, RNA-specific 0.098942
IL1A interleukin 1, alpha 0.098782
KNTC1 kinetochore associated 1 0.098754
PENK proenkephalin 0.098659
FAM134B family with sequence similarity 134, member B 0.098344
EDN1 endothelin 1 0.09829
PEX10 peroxisomal biogenesis factor 10 0.098276
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.097372
SUMF2 sulfatase modifying factor 2 0.096939
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.096465
MLPH melanophilin 0.096044
IL17A interleukin 17A 0.095816
CTSS cathepsin S 0.095801
SZRD1 SUZ RNA binding domain containing 1 0.095702
NELFCD negative elongation factor complex member C/D 0.095147
MON1A MON1 secretory trafficking family member A 0.094933
EPHA2 EPH receptor A2 0.094862
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.094862
SMTNL1 smoothelin-like 1 0.094775
BSN bassoon presynaptic cytomatrix protein 0.094499
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 0.09447
THAP1 THAP domain containing, apoptosis associated protein 1 0.094136
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 0.093875
VCL vinculin 0.093861
GPI glucose-6-phosphate isomerase 0.093542
FLAD1 flavin adenine dinucleotide synthetase 1 0.093498
CRBN cereblon 0.093099
COL5A1 collagen, type V, alpha 1 0.093025
WNK1 WNK lysine deficient protein kinase 1 0.092891
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.092877
MFAP2 microfibrillar-associated protein 2 0.092773
AGK acylglycerol kinase 0.092463
PDLIM5 PDZ and LIM domain 5 0.092433
SS18 synovial sarcoma translocation, chromosome 18 0.091973
YIPF1 Yip1 domain family, member 1 0.091867
MMP10 matrix metallopeptidase 10 0.090769
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.090708
BRS3 bombesin-like receptor 3 0.090556
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.090234
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.090203
PDIA3 protein disulfide isomerase family A, member 3 0.089744
RIPK4 receptor-interacting serine-threonine kinase 4 0.089576
SNCB synuclein, beta 0.088741
DST dystonin 0.088585
MLX MLX, MAX dimerization protein 0.088585
CYGB cytoglobin 0.08815
LACTB lactamase, beta 0.08746
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.086813
SLC22A18 solute carrier family 22, member 18 0.086702
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.086686
GRHL1 grainyhead-like 1 (Drosophila) 0.086276
LHB luteinizing hormone beta polypeptide 0.08618
HNF1A HNF1 homeobox A 0.085987
LGALS7 lectin, galactoside-binding, soluble, 7 0.085891
NCS1 neuronal calcium sensor 1 0.085682
KRT81 keratin 81, type II 0.085618
EFNA5 ephrin-A5 0.085586
CHAD chondroadherin 0.085426
NAGLU N-acetylglucosaminidase, alpha 0.085122
FOXP3 forkhead box P3 0.084656
FAP fibroblast activation protein, alpha 0.08438
LST1 leukocyte specific transcript 1 0.083665
CEL carboxyl ester lipase 0.0836
HP haptoglobin 0.083373
PCP2 Purkinje cell protein 2 0.083292
MID2 midline 2 0.083112
DMRTA1 DMRT-like family A1 0.083013
HPR haptoglobin-related protein 0.082848
CES1 carboxylesterase 1 0.082783
COL2A1 collagen, type II, alpha 1 0.0827
AGRP agouti related neuropeptide 0.082125
FGB fibrinogen beta chain 0.081398
IGLV5-52 immunoglobulin lambda variable 5-52 0.081149
ADGRV1 adhesion G protein-coupled receptor V1 0.080883
LRP5 low density lipoprotein receptor-related protein 5 0.080633
NTS neurotensin 0.080384
C1QA complement component 1, q subcomponent, A chain 0.080118
SETD1A SET domain containing 1A 0.080101
TOP3A topoisomerase (DNA) III alpha 0.079983
GNAS GNAS complex locus 0.079866
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.079513
GPR162 G protein-coupled receptor 162 0.078807
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.078572
GRM1 glutamate receptor, metabotropic 1 0.078453
EWSR1 EWS RNA-binding protein 1 0.078368
WFS1 Wolfram syndrome 1 (wolframin) 0.078335
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.078267
C1ORF167 chromosome 1 open reading frame 167 0.078131
ANXA3 annexin A3 0.077452
S100B S100 calcium binding protein B 0.077198
GAP43 growth associated protein 43 0.077113
ANO1 anoctamin 1, calcium activated chloride channel 0.077012
C4A complement component 4A (Rodgers blood group) 0.076618
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.076413
LPIN1 lipin 1 0.076224
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.075831
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.074835
DAXX death-domain associated protein 0.074645
RFXANK regulatory factor X-associated ankyrin-containing protein 0.074628
NPC1 Niemann-Pick disease, type C1 0.07399
GPANK1 G patch domain and ankyrin repeats 1 0.073749
MAGEC1 melanoma antigen family C1 0.072933
HLA-DMA major histocompatibility complex, class II, DM alpha 0.07224
BCR breakpoint cluster region 0.071629
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.070461
PTPRN protein tyrosine phosphatase, receptor type, N 0.070426
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.069777
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.069338
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.069233
GLG1 golgi glycoprotein 1 0.069128
CFP complement factor properdin 0.069076
HM13 histocompatibility (minor) 13 0.068953
CLEC11A C-type lectin domain family 11, member A 0.068637
RAET1E retinoic acid early transcript 1E 0.068531
SQLE squalene epoxidase 0.068285
ZNF135 zinc finger protein 135 0.068126
FRS2 fibroblast growth factor receptor substrate 2 0.067986
F3 coagulation factor III (thromboplastin, tissue factor) 0.067704
WARS tryptophanyl-tRNA synthetase 0.067669
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.067652
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.067493
TRAF3 TNF receptor-associated factor 3 0.066983
GYPC glycophorin C (Gerbich blood group) 0.066824
PNMA1 paraneoplastic Ma antigen 1 0.066683
KAT8 K(lysine) acetyltransferase 8 0.066189
NANP N-acetylneuraminic acid phosphatase 0.065819
CDSN corneodesmosin 0.065608
FUS FUS RNA binding protein 0.065148
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.065131
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.06506
CALCRL calcitonin receptor-like 0.064989
MYOG myogenin (myogenic factor 4) 0.064989
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.064848
PNMA2 paraneoplastic Ma antigen 2 0.064707
VIM vimentin 0.064671
MANBA mannosidase, beta A, lysosomal 0.064442
AHSG alpha-2-HS-glycoprotein 0.064424
FMN1 formin 1 0.064248
IFNG interferon, gamma 0.064018
PDHX pyruvate dehydrogenase complex, component X 0.063842
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.063205
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.063135
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.063117
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.063028
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.062905
KRT14 keratin 14, type I 0.062728
MYOD1 myogenic differentiation 1 0.062622
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.062216
CLDN1 claudin 1 0.061792
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.061721
CD1D CD1d molecule 0.061686
MAPK14 mitogen-activated protein kinase 14 0.061562
CLDN7 claudin 7 0.061139
VIT vitrin 0.061121
MSR1 macrophage scavenger receptor 1 0.060997
BLK BLK proto-oncogene, Src family tyrosine kinase 0.060662
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.060592
LAMA2 laminin, alpha 2 0.060433
FYB FYN binding protein 0.060221
EEA1 early endosome antigen 1 0.060133
FLNA filamin A, alpha 0.060062
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.060062
REEP5 receptor accessory protein 5 0.060045
PRNP prion protein 0.060045
PER2 period circadian clock 2 0.059833
SP7 Sp7 transcription factor 0.059833
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.059745
CTSH cathepsin H 0.059692
CALCR calcitonin receptor 0.059604
ASGR1 asialoglycoprotein receptor 1 0.059604
CCL27 chemokine (C-C motif) ligand 27 0.059533
PMM2 phosphomannomutase 2 0.059463
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.059428
KIAA0196 KIAA0196 0.059269
XK X-linked Kx blood group 0.059234
ASPN asporin 0.059146
TBX21 T-box 21 0.059111
SV2A synaptic vesicle glycoprotein 2A 0.059005
CLEC3A C-type lectin domain family 3, member A 0.058987
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.058899
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.058899
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.058899
GIF gastric intrinsic factor (vitamin B synthesis) 0.058811
IBSP integrin-binding sialoprotein 0.058811
CLEC2B C-type lectin domain family 2, member B 0.058758
REEP1 receptor accessory protein 1 0.0586
CLU clusterin 0.058336
CD83 CD83 molecule 0.058301
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.057896
CARD17 caspase recruitment domain family, member 17 0.057773
HSPG2 heparan sulfate proteoglycan 2 0.057703
TARDBP TAR DNA binding protein 0.057685
PART1 prostate androgen-regulated transcript 1 (non-protein coding) 0.057633
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.05758
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.057545
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.05751
TNC tenascin C 0.05751
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.057404
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.057387
KRT86 keratin 86, type II 0.057352
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.057317
CD46 CD46 molecule, complement regulatory protein 0.057194
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.057194
TYRO3 TYRO3 protein tyrosine kinase 0.057176
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.057159
FASLG Fas ligand (TNF superfamily, member 6) 0.057124
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.057089
ZFYVE26 zinc finger, FYVE domain containing 26 0.057053
ADA adenosine deaminase 0.057036
NCAM1 neural cell adhesion molecule 1 0.056983
TJP1 tight junction protein 1 0.056966
IL5 interleukin 5 0.056966
CABIN1 calcineurin binding protein 1 0.056896
SREBF1 sterol regulatory element binding transcription factor 1 0.056878
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.056861
HLA-A major histocompatibility complex, class I, A 0.056843
PRIMA1 proline rich membrane anchor 1 0.05672
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.05672
EDNRB endothelin receptor type B 0.056703
PSPH phosphoserine phosphatase 0.056703
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.056668
MGP matrix Gla protein 0.056615
PARP1 poly (ADP-ribose) polymerase 1 0.05658
TIMP2 TIMP metallopeptidase inhibitor 2 0.056422
APOD apolipoprotein D 0.056317
LPO lactoperoxidase 0.05623
ECI1 enoyl-CoA delta isomerase 1 0.056037
TRO trophinin 0.055967
ANPEP alanyl (membrane) aminopeptidase 0.05595
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.05595
TYR tyrosinase 0.055775
HPD 4-hydroxyphenylpyruvate dioxygenase 0.055705
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.055635
MEIS1 Meis homeobox 1 0.0556