pentoxyverine-4649 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the pentoxyverine-4649 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADORA1 adenosine A1 receptor
ALMS1 Alstrom syndrome protein 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASCL1 achaete-scute family bHLH transcription factor 1
ASTN1 astrotactin 1
B3GAT1 beta-1,3-glucuronyltransferase 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAAT bile acid CoA:amino acid N-acyltransferase
BTNL2 butyrophilin-like 2
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACYBP calcyclin binding protein
CNGB3 cyclic nucleotide gated channel beta 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COMP cartilage oligomeric matrix protein
CRP C-reactive protein, pentraxin-related
CXCR6 chemokine (C-X-C motif) receptor 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCTN1 dynactin 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
EHD2 EH-domain containing 2
ELMO1 engulfment and cell motility 1
ERAP1 endoplasmic reticulum aminopeptidase 1
EXOC7 exocyst complex component 7
FBRS fibrosin
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAST gastrin
GLI2 GLI family zinc finger 2
GTPBP1 GTP binding protein 1
H2AFJ H2A histone family, member J
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXD9 homeobox D9
HPCAL4 hippocalcin like 4
HPR haptoglobin-related protein
HPS1 Hermansky-Pudlak syndrome 1
HSPB3 heat shock 27kDa protein 3
INS insulin
KCTD13 potassium channel tetramerization domain containing 13
KDM4B lysine (K)-specific demethylase 4B
KIF21B kinesin family member 21B
KSR1 kinase suppressor of ras 1
LINC00216 long intergenic non-protein coding RNA 216
LINC00652 long intergenic non-protein coding RNA 652
LOC100131532 uncharacterized LOC100131532
LOC100287387 uncharacterized LOC100287387
MEG3 maternally expressed 3 (non-protein coding)
MKL1 megakaryoblastic leukemia (translocation) 1
MMP11 matrix metallopeptidase 11
MTSS1 metastasis suppressor 1
MYH14 myosin, heavy chain 14, non-muscle
NOP16 NOP16 nucleolar protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OMD osteomodulin
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PADI4 peptidyl arginine deiminase, type IV
PAX4 paired box 4
PCDH11Y protocadherin 11 Y-linked
PCDHB17P protocadherin beta 17 pseudogene
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLA2G3 phospholipase A2, group III
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POU6F1 POU class 6 homeobox 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRDM1 PR domain containing 1, with ZNF domain
PRTN3 proteinase 3
RGS12 regulator of G-protein signaling 12
RHAG Rh-associated glycoprotein
RIN3 Ras and Rab interactor 3
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCN2B sodium channel, voltage gated, type II beta subunit
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A6 solute carrier family 16, member 6
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC39A9 solute carrier family 39, member 9
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SSX1 synovial sarcoma, X breakpoint 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TBKBP1 TBK1 binding protein 1
TDRD1 tudor domain containing 1
TDRD12 tudor domain containing 12
TESPA1 thymocyte expressed, positive selection associated 1
THOC5 THO complex 5
TMEM140 transmembrane protein 140
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TP63 tumor protein p63
TREM1 triggering receptor expressed on myeloid cells 1
WNT8B wingless-type MMTV integration site family, member 8B
ZNF223 zinc finger protein 223
ZNF37BP zinc finger protein 37B, pseudogene
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAT1 adenosine deaminase, tRNA-specific 1
ADGRG6 adhesion G protein-coupled receptor G6
AGPS alkylglycerone phosphate synthase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMT aminomethyltransferase
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CASD1 CAS1 domain containing 1
CASZ1 castor zinc finger 1
CCDC85C coiled-coil domain containing 85C
CD68 CD68 molecule
CEP131 centrosomal protein 131kDa
CISH cytokine inducible SH2-containing protein
CNN1 calponin 1, basic, smooth muscle
CNTLN centlein, centrosomal protein
DCAF4 DDB1 and CUL4 associated factor 4
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
ELOVL4 ELOVL fatty acid elongase 4
EPHB6 EPH receptor B6
EPN3 epsin 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM118A family with sequence similarity 118, member A
FBXO2 F-box protein 2
FBXO46 F-box protein 46
FKBP5 FK506 binding protein 5
FSD1 fibronectin type III and SPRY domain containing 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
HELZ helicase with zinc finger
HOXA1 homeobox A1
IL7 interleukin 7
KDM7A lysine (K)-specific demethylase 7A
KRT34 keratin 34, type I
KRT8P12 keratin 8 pseudogene 12
LMNB2 lamin B2
LOC157562 uncharacterized LOC157562
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRK1 leucine-rich repeat kinase 1
LUC7L LUC7-like (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
MANBA mannosidase, beta A, lysosomal
MED31 mediator complex subunit 31
MNX1 motor neuron and pancreas homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NPFFR1 neuropeptide FF receptor 1
P3H2 prolyl 3-hydroxylase 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PCOLCE procollagen C-endopeptidase enhancer
PLCD1 phospholipase C, delta 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPT2 palmitoyl-protein thioesterase 2
PTK7 protein tyrosine kinase 7 (inactive)
RAB17 RAB17, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RECQL4 RecQ protein-like 4
RFWD3 ring finger and WD repeat domain 3
ROM1 retinal outer segment membrane protein 1
RUSC2 RUN and SH3 domain containing 2
RWDD2A RWD domain containing 2A
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SH2D4A SH2 domain containing 4A
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SND1-IT1 SND1 intronic transcript 1
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
STEAP4 STEAP family member 4
THBS3 thrombospondin 3
THOP1 thimet oligopeptidase 1
TMEM156 transmembrane protein 156
TOR4A torsin family 4, member A
TUBB2B tubulin, beta 2B class IIb
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
YY2 YY2 transcription factor
ZFHX3 zinc finger homeobox 3
ZNF222 zinc finger protein 222
ZNF532 zinc finger protein 532
ZNF671 zinc finger protein 671
ZNF76 zinc finger protein 76