pentolonium-4699 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the pentolonium-4699 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADGRG2 adhesion G protein-coupled receptor G2
ANAPC13 anaphase promoting complex subunit 13
ANGEL2 angel homolog 2 (Drosophila)
APOLD1 apolipoprotein L domain containing 1
ATN1 atrophin 1
BTG2 BTG family, member 2
C10ORF95 chromosome 10 open reading frame 95
CALML5 calmodulin-like 5
CCDC121 coiled-coil domain containing 121
CD34 CD34 molecule
CD47 CD47 molecule
CDC14A cell division cycle 14A
CDC42 cell division cycle 42
CEMIP cell migration inducing protein, hyaluronan binding
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
COMMD10 COMM domain containing 10
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CXCR4 chemokine (C-X-C motif) receptor 4
DCAF11 DDB1 and CUL4 associated factor 11
DGAT1 diacylglycerol O-acyltransferase 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DOK4 docking protein 4
DSC2 desmocollin 2
EDRF1 erythroid differentiation regulatory factor 1
FH fumarate hydratase
FN1 fibronectin 1
GALC galactosylceramidase
GDAP1 ganglioside induced differentiation associated protein 1
GID4 GID complex subunit 4
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GM2A GM2 ganglioside activator
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAS GNAS complex locus
GPATCH4 G patch domain containing 4
GULP1 GULP, engulfment adaptor PTB domain containing 1
HR hair growth associated
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INCENP inner centromere protein antigens 135/155kDa
INHBA inhibin, beta A
KITLG KIT ligand
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAU2 MAU2 sister chromatid cohesion factor
MBTPS2 membrane-bound transcription factor peptidase, site 2
MORC1 MORC family CW-type zinc finger 1
MTMR2 myotubularin related protein 2
MYB v-myb avian myeloblastosis viral oncogene homolog
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
OSBP2 oxysterol binding protein 2
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAOX polyamine oxidase (exo-N4-amino)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHB12 protocadherin beta 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLK4 polo-like kinase 4
PRKCA protein kinase C, alpha
PRKD3 protein kinase D3
PSG1 pregnancy specific beta-1-glycoprotein 1
PVR poliovirus receptor
QKI QKI, KH domain containing, RNA binding
RASAL2 RAS protein activator like 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBBP9 retinoblastoma binding protein 9
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIMS2 regulating synaptic membrane exocytosis 2
RRAGB Ras-related GTP binding B
RRM1 ribonucleotide reductase M1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RXRB retinoid X receptor, beta
SCAMP1 secretory carrier membrane protein 1
SCAND2P SCAN domain containing 2 pseudogene
SFRP4 secreted frizzled-related protein 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRR3 small proline-rich protein 3
SSBP2 single-stranded DNA binding protein 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYN2 synapsin II
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAPBP TAP binding protein (tapasin)
TCP11L1 t-complex 11, testis-specific-like 1
TMLHE trimethyllysine hydroxylase, epsilon
TRIM23 tripartite motif containing 23
UNC5B unc-5 homolog B (C. elegans)
WFDC2 WAP four-disulfide core domain 2
YIPF4 Yip1 domain family, member 4
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF174 zinc finger protein 174

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADGRE5 adhesion G protein-coupled receptor E5
ALPK1 alpha-kinase 1
ARC activity-regulated cytoskeleton-associated protein
ARHGAP4 Rho GTPase activating protein 4
BCL9 B-cell CLL/lymphoma 9
BFSP1 beaded filament structural protein 1, filensin
BPGM 2,3-bisphosphoglycerate mutase
C11ORF63 chromosome 11 open reading frame 63
C2ORF54 chromosome 2 open reading frame 54
CAPRIN2 caprin family member 2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CINP cyclin-dependent kinase 2 interacting protein
CLCN6 chloride channel, voltage-sensitive 6
CORO7 coronin 7
CRY2 cryptochrome circadian clock 2
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DEAF1 DEAF1 transcription factor
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
EXD3 exonuclease 3'-5' domain containing 3
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM131A family with sequence similarity 131, member A
FANCE Fanconi anemia, complementation group E
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLJ21369 uncharacterized protein FLJ21369
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPC3 glypican 3
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HDAC5 histone deacetylase 5
HIST1H2AI histone cluster 1, H2ai
HIST1H2BN histone cluster 1, H2bn
HIST2H2AA3 histone cluster 2, H2aa3
HOXC8 homeobox C8
HSPB6 heat shock protein, alpha-crystallin-related, B6
JMJD4 jumonji domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KPNA5 karyopherin alpha 5 (importin alpha 6)
MFSD11 major facilitator superfamily domain containing 11
MTA2 metastasis associated 1 family, member 2
MYLK myosin light chain kinase
N4BP3 NEDD4 binding protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD1 neuronal differentiation 1
NUP62CL nucleoporin 62kDa C-terminal like
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
POLM polymerase (DNA directed), mu
POM121 POM121 transmembrane nucleoporin
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100A9 S100 calcium binding protein A9
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP4 STEAP family member 4
TICAM1 toll-like receptor adaptor molecule 1
TIGD6 tigger transposable element derived 6
TMEM132A transmembrane protein 132A
TMEM212 transmembrane protein 212
TMEM57 transmembrane protein 57
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNRC6B trinucleotide repeat containing 6B
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBB2B tubulin, beta 2B class IIb
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
VAV1 vav 1 guanine nucleotide exchange factor
VIM vimentin
WDR19 WD repeat domain 19
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB22 zinc finger and BTB domain containing 22
ZC3H3 zinc finger CCCH-type containing 3
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747