pentolonium-2343 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the pentolonium-2343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD55 ankyrin repeat domain 55
APOM apolipoprotein M
ASB7 ankyrin repeat and SOCS box containing 7
C1ORF21 chromosome 1 open reading frame 21
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC9 coiled-coil domain containing 9
CD86 CD86 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDR2L cerebellar degeneration-related protein 2-like
CDRT1 CMT1A duplicated region transcript 1
CELF1 CUGBP, Elav-like family member 1
CEP250 centrosomal protein 250kDa
CIDEC cell death-inducing DFFA-like effector c
CKB creatine kinase, brain
CLCN4 chloride channel, voltage-sensitive 4
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COX4I1 cytochrome c oxidase subunit IV isoform 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREM cAMP responsive element modulator
CRY2 cryptochrome circadian clock 2
CTNNBL1 catenin, beta like 1
DGKE diacylglycerol kinase, epsilon 64kDa
DHODH dihydroorotate dehydrogenase (quinone)
DNASE2 deoxyribonuclease II, lysosomal
DNPEP aspartyl aminopeptidase
DOCK5 dedicator of cytokinesis 5
DRD2 dopamine receptor D2
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
E2F4 E2F transcription factor 4, p107/p130-binding
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EMILIN2 elastin microfibril interfacer 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
F12 coagulation factor XII (Hageman factor)
FAM3A family with sequence similarity 3, member A
FAM65A family with sequence similarity 65, member A
FAS Fas cell surface death receptor
FURIN furin (paired basic amino acid cleaving enzyme)
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GMEB1 glucocorticoid modulatory element binding protein 1
GOSR2 golgi SNAP receptor complex member 2
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HOPX HOP homeobox
HRH1 histamine receptor H1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IL17RA interleukin 17 receptor A
IL1R2 interleukin 1 receptor, type II
INO80B INO80 complex subunit B
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD13 potassium channel tetramerization domain containing 13
LOC100287590 uncharacterized LOC100287590
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRK1 leucine-rich repeat kinase 1
MAOA monoamine oxidase A
MMP9 matrix metallopeptidase 9
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPZL1 myelin protein zero-like 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NOL12 nucleolar protein 12
PHACTR2 phosphatase and actin regulator 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIAS3 protein inhibitor of activated STAT, 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POU3F2 POU class 3 homeobox 2
PQLC2 PQ loop repeat containing 2
PRKCZ protein kinase C, zeta
PSD3 pleckstrin and Sec7 domain containing 3
PTPRJ protein tyrosine phosphatase, receptor type, J
R3HDM4 R3H domain containing 4
RAB35 RAB35, member RAS oncogene family
RANGAP1 Ran GTPase activating protein 1
RBM42 RNA binding motif protein 42
RFPL3 ret finger protein-like 3
RGS3 regulator of G-protein signaling 3
RPL13 ribosomal protein L13
SCUBE3 signal peptide, CUB domain, EGF-like 3
SH2B1 SH2B adaptor protein 1
SIDT2 SID1 transmembrane family, member 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX4 SRY (sex determining region Y)-box 4
SYT11 synaptotagmin XI
TCF3 transcription factor 3
TECPR2 tectonin beta-propeller repeat containing 2
TRAPPC9 trafficking protein particle complex 9
UBE3B ubiquitin protein ligase E3B
UHRF1BP1L UHRF1 binding protein 1-like
USP48 ubiquitin specific peptidase 48
WDR4 WD repeat domain 4
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACO1 aconitase 1, soluble
ACPP acid phosphatase, prostate
AHCTF1 AT hook containing transcription factor 1
AHDC1 AT hook, DNA binding motif, containing 1
ANKRD36B ankyrin repeat domain 36B
ASCC2 activating signal cointegrator 1 complex subunit 2
ATF7IP2 activating transcription factor 7 interacting protein 2
BMP15 bone morphogenetic protein 15
BPI bactericidal/permeability-increasing protein
C19ORF40 chromosome 19 open reading frame 40
C7ORF69 chromosome 7 open reading frame 69
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC88C coiled-coil domain containing 88C
CDK3 cyclin-dependent kinase 3
CENPB centromere protein B, 80kDa
CLCF1 cardiotrophin-like cytokine factor 1
CLCN6 chloride channel, voltage-sensitive 6
CLEC7A C-type lectin domain family 7, member A
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDIT3 DNA-damage-inducible transcript 3
DENND2D DENN/MADD domain containing 2D
DSPP dentin sialophosphoprotein
DUSP5 dual specificity phosphatase 5
DYM dymeclin
E4F1 E4F transcription factor 1
EDAR ectodysplasin A receptor
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EML4 echinoderm microtubule associated protein like 4
ETAA1 Ewing tumor-associated antigen 1
FAM57A family with sequence similarity 57, member A
FILIP1L filamin A interacting protein 1-like
FLJ21369 uncharacterized protein FLJ21369
GIPC1 GIPC PDZ domain containing family, member 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BF histone cluster 1, H2bf
HOOK2 hook microtubule-tethering protein 2
ICK intestinal cell (MAK-like) kinase
IER3 immediate early response 3
IFT46 intraflagellar transport 46
IRF9 interferon regulatory factor 9
KAT2B K(lysine) acetyltransferase 2B
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLHL21 kelch-like family member 21
KLK5 kallikrein-related peptidase 5
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAX1 lymphocyte transmembrane adaptor 1
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAGEB2 melanoma antigen family B2
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP6D1 MAP6 domain containing 1
MBNL3 muscleblind-like splicing regulator 3
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
ODF2 outer dense fiber of sperm tails 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLA2G15 phospholipase A2, group XV
POMT1 protein-O-mannosyltransferase 1
PPCS phosphopantothenoylcysteine synthetase
PSKH1 protein serine kinase H1
PTTG3P pituitary tumor-transforming 3, pseudogene
PTX3 pentraxin 3, long
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB8B RAB8B, member RAS oncogene family
RBL1 retinoblastoma-like 1
RCAN3 RCAN family member 3
RNF31 ring finger protein 31
RPAP1 RNA polymerase II associated protein 1
RPL23AP7 ribosomal protein L23a pseudogene 7
RSF1 remodeling and spacing factor 1
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SLC22A18 solute carrier family 22, member 18
SMR3A submaxillary gland androgen regulated protein 3A
SNAP29 synaptosomal-associated protein, 29kDa
SOX12 SRY (sex determining region Y)-box 12
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP1 six transmembrane epithelial antigen of the prostate 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
THEM6 thioesterase superfamily member 6
THOC1 THO complex 1
TIGD6 tigger transposable element derived 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMC7 transmembrane channel-like 7
TMEM134 transmembrane protein 134
TMEM212 transmembrane protein 212
UGDH UDP-glucose 6-dehydrogenase
WDR91 WD repeat domain 91
XAF1 XIAP associated factor 1
ZBED8 zinc finger, BED-type containing 8
ZMAT3 zinc finger, matrin-type 3
ZMYM1 zinc finger, MYM-type 1
ZNF668 zinc finger protein 668