pentetic acid-5629 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pentetic acid-5629 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY2 adenylate cyclase 2 (brain)
ADM adrenomedullin
AGO4 argonaute RISC catalytic component 4
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATG10 autophagy related 10
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATN1 atrophin 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP8A bone morphogenetic protein 8a
BTG2 BTG family, member 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CD4 CD4 molecule
CD52 CD52 molecule
CD8A CD8a molecule
CEP41 centrosomal protein 41kDa
CNTLN centlein, centrosomal protein
COL5A1 collagen, type V, alpha 1
CYLD cylindromatosis (turban tumor syndrome)
DCTN1 dynactin 1
DGCR8 DGCR8 microprocessor complex subunit
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DMP1 dentin matrix acidic phosphoprotein 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPP4 dipeptidyl-peptidase 4
EPHB1 EPH receptor B1
FBXO21 F-box protein 21
FFAR3 free fatty acid receptor 3
FHIT fragile histidine triad
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GIF gastric intrinsic factor (vitamin B synthesis)
GLP1R glucagon-like peptide 1 receptor
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
HRASLS2 HRAS-like suppressor 2
IFNA2 interferon, alpha 2
IL11 interleukin 11
IL2RG interleukin 2 receptor, gamma
ING4 inhibitor of growth family, member 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLHL25 kelch-like family member 25
KRT75 keratin 75, type II
KSR1 kinase suppressor of ras 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAPK10 mitogen-activated protein kinase 10
MASP2 mannan-binding lectin serine peptidase 2
MCAM melanoma cell adhesion molecule
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MLANA melan-A
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MPZ myelin protein zero
MYBPC3 myosin binding protein C, cardiac
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCKIPSD NCK interacting protein with SH3 domain
NCOR2 nuclear receptor corepressor 2
NOX3 NADPH oxidase 3
NPR1 natriuretic peptide receptor 1
NRF1 nuclear respiratory factor 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PCDHB12 protocadherin beta 12
PCDHGA9 protocadherin gamma subfamily A, 9
PECAM1 platelet/endothelial cell adhesion molecule 1
PKDREJ polycystin (PKD) family receptor for egg jelly
PLCD1 phospholipase C, delta 1
PMFBP1 polyamine modulated factor 1 binding protein 1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLL polymerase (DNA directed), lambda
PON3 paraoxonase 3
PTCRA pre T-cell antigen receptor alpha
PTPRJ protein tyrosine phosphatase, receptor type, J
PVALB parvalbumin
PYY peptide YY
RAP1GAP RAP1 GTPase activating protein
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RUNDC3A RUN domain containing 3A
SARM1 sterile alpha and TIR motif containing 1
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SRSF7 serine/arginine-rich splicing factor 7
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBXA2R thromboxane A2 receptor
TM4SF20 transmembrane 4 L six family member 20
TSNAXIP1 translin-associated factor X interacting protein 1
UBE3A ubiquitin protein ligase E3A
WSCD1 WSC domain containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF639 zinc finger protein 639
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADAP2 ArfGAP with dual PH domains 2
ANKRD28 ankyrin repeat domain 28
APOLD1 apolipoprotein L domain containing 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMCX2 armadillo repeat containing, X-linked 2
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
C17ORF80 chromosome 17 open reading frame 80
C5AR2 complement component 5a receptor 2
CCDC71 coiled-coil domain containing 71
CDK20 cyclin-dependent kinase 20
CES3 carboxylesterase 3
CFAP45 cilia and flagella associated protein 45
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN6 chloride channel, voltage-sensitive 6
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCAF4 DDB1 and CUL4 associated factor 4
DDIT3 DNA-damage-inducible transcript 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYSF dysferlin
ETV6 ets variant 6
F9 coagulation factor IX
FFAR2 free fatty acid receptor 2
FGF23 fibroblast growth factor 23
FRK fyn-related Src family tyrosine kinase
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAMT guanidinoacetate N-methyltransferase
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPR39 G protein-coupled receptor 39
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC5 histone deacetylase 5
HIST1H3E histone cluster 1, H3e
HP1BP3 heterochromatin protein 1, binding protein 3
IFT140 intraflagellar transport 140
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCTD20 potassium channel tetramerization domain containing 20
KCTD7 potassium channel tetramerization domain containing 7
KIAA0319L KIAA0319-like
KPNA5 karyopherin alpha 5 (importin alpha 6)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC61 leucine rich repeat containing 61
LYRM9 LYR motif containing 9
MAGEF1 melanoma antigen family F1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MGC12488
MRPL41 mitochondrial ribosomal protein L41
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OVGP1 oviductal glycoprotein 1, 120kDa
OXCT2 3-oxoacid CoA transferase 2
PARD6B par-6 family cell polarity regulator beta
PDE8B phosphodiesterase 8B
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PITX2 paired-like homeodomain 2
PLA2G3 phospholipase A2, group III
PODNL1 podocan-like 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PROCR protein C receptor, endothelial
PTDSS2 phosphatidylserine synthase 2
RAB30 RAB30, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF126P1 ring finger protein 126 pseudogene 1
S100A7 S100 calcium binding protein A7
SENP7 SUMO1/sentrin specific peptidase 7
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRT2 sirtuin 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC12A8 solute carrier family 12, member 8
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SSTR4 somatostatin receptor 4
STRA6 stimulated by retinoic acid 6
SULT4A1 sulfotransferase family 4A, member 1
SYNC syncoilin, intermediate filament protein
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TMEM45A transmembrane protein 45A
TRDMT1 tRNA aspartic acid methyltransferase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB44 zinc finger and BTB domain containing 44
ZFP37 ZFP37 zinc finger protein
ZMAT5 zinc finger, matrin-type 5
ZNF350 zinc finger protein 350
ZNF446 zinc finger protein 446
ZNF484 zinc finger protein 484
ZNF532 zinc finger protein 532
ZNF750 zinc finger protein 750