pentetic acid-5264 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pentetic acid-5264 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
AQP7 aquaporin 7
ARHGAP4 Rho GTPase activating protein 4
ARID4B AT rich interactive domain 4B (RBP1-like)
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATXN7L1 ataxin 7-like 1
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BST2 bone marrow stromal cell antigen 2
BTN3A1 butyrophilin, subfamily 3, member A1
C22ORF46 chromosome 22 open reading frame 46
CD2 CD2 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDKN2A cyclin-dependent kinase inhibitor 2A
CDO1 cysteine dioxygenase type 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL19A1 collagen, type XIX, alpha 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
CPA2 carboxypeptidase A2 (pancreatic)
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DHRS7 dehydrogenase/reductase (SDR family) member 7
DIO2 deiodinase, iodothyronine, type II
DRD2 dopamine receptor D2
DUSP10 dual specificity phosphatase 10
EFNB3 ephrin-B3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EMID1 EMI domain containing 1
ERN1 endoplasmic reticulum to nucleus signaling 1
FBXO41 F-box protein 41
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFBP1 fibroblast growth factor binding protein 1
FLNC filamin C, gamma
FOXG1 forkhead box G1
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GLB1L galactosidase, beta 1-like
GPR143 G protein-coupled receptor 143
GSTTP1 glutathione S-transferase theta pseudogene 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNK5 potassium channel, two pore domain subfamily K, member 5
KLHL35 kelch-like family member 35
LARP4B La ribonucleoprotein domain family, member 4B
MC5R melanocortin 5 receptor
MSI1 musashi RNA-binding protein 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MVB12B multivesicular body subunit 12B
MYCNOS MYCN opposite strand
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NPR3 natriuretic peptide receptor 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFM1 olfactomedin 1
OXCT2 3-oxoacid CoA transferase 2
PAX9 paired box 9
PCDH1 protocadherin 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PHF20L1 PHD finger protein 20-like 1
PHF7 PHD finger protein 7
PHF8 PHD finger protein 8
PIGR polymeric immunoglobulin receptor
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK3 polo-like kinase 3
PRDM14 PR domain containing 14
PRKCA protein kinase C, alpha
PSAT1 phosphoserine aminotransferase 1
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB40AL RAB40A, member RAS oncogene family-like
RFPL2 ret finger protein-like 2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRPA signal-regulatory protein alpha
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAP25 synaptosomal-associated protein, 25kDa
SNTA1 syntrophin, alpha 1
STK24 serine/threonine kinase 24
TAS2R1 taste receptor, type 2, member 1
TBKBP1 TBK1 binding protein 1
THRB thyroid hormone receptor, beta
TMCC2 transmembrane and coiled-coil domain family 2
TMPRSS2 transmembrane protease, serine 2
TNN tenascin N
TONSL tonsoku-like, DNA repair protein
TREX1 three prime repair exonuclease 1
TRH thyrotropin-releasing hormone
TRPM3 transient receptor potential cation channel, subfamily M, member 3
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UPK3B uroplakin 3B
WFDC2 WAP four-disulfide core domain 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTL8 actin-like 8
ALPK1 alpha-kinase 1
ARC activity-regulated cytoskeleton-associated protein
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
ATG2A autophagy related 2A
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BHLHE41 basic helix-loop-helix family, member e41
C14ORF79 chromosome 14 open reading frame 79
C2ORF27A chromosome 2 open reading frame 27A
C5 complement component 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBR4 carbonyl reductase 4
CCDC85C coiled-coil domain containing 85C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CENPO centromere protein O
CGREF1 cell growth regulator with EF-hand domain 1
CHM choroideremia (Rab escort protein 1)
CHRM3 cholinergic receptor, muscarinic 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIDEC cell death-inducing DFFA-like effector c
CLCN6 chloride channel, voltage-sensitive 6
CLDN1 claudin 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CSF1R colony stimulating factor 1 receptor
CXXC4 CXXC finger protein 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGAT1 diacylglycerol O-acyltransferase 1
DNM1 dynamin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EXOC6B exocyst complex component 6B
FAM184A family with sequence similarity 184, member A
FBXO4 F-box protein 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GPR1 G protein-coupled receptor 1
GPR19 G protein-coupled receptor 19
GPR85 G protein-coupled receptor 85
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRB7 growth factor receptor-bound protein 7
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H1E histone cluster 1, H1e
HIST1H2BO histone cluster 1, H2bo
HIST1H4E histone cluster 1, H4e
HLA-DMA major histocompatibility complex, class II, DM alpha
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC5 homeobox C5
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
KLHL26 kelch-like family member 26
KREMEN2 kringle containing transmembrane protein 2
LGALS4 lectin, galactoside-binding, soluble, 4
LMNB1 lamin B1
LPPR1 lipid phosphate phosphatase-related protein type 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MOSPD3 motile sperm domain containing 3
MYOZ3 myozenin 3
NDE1 nudE neurodevelopment protein 1
NOL12 nucleolar protein 12
NT5E 5'-nucleotidase, ecto (CD73)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PCDHA5 protocadherin alpha 5
PCDHB13 protocadherin beta 13
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRR4 proline rich 4 (lacrimal)
PRSS53 protease, serine, 53
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFTN1 raftlin, lipid raft linker 1
RPL10L ribosomal protein L10-like
SECTM1 secreted and transmembrane 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SRPX sushi-repeat containing protein, X-linked
STEAP1 six transmembrane epithelial antigen of the prostate 1
SYNGR3 synaptogyrin 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TARP TCR gamma alternate reading frame protein
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR5 toll-like receptor 5
TOM1 target of myb1 (chicken)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL1 tubulin tyrosine ligase-like family member 1
UBTD1 ubiquitin domain containing 1
USP27X ubiquitin specific peptidase 27, X-linked
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR19 WD repeat domain 19
WDR33 WD repeat domain 33
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZNF516 zinc finger protein 516