pentetic acid-4669 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pentetic acid-4669 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX12 arachidonate 12-lipoxygenase
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APC adenomatous polyposis coli
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BMP8A bone morphogenetic protein 8a
C18ORF25 chromosome 18 open reading frame 25
CCNJL cyclin J-like
CLTA clathrin, light chain A
COL4A6 collagen, type IV, alpha 6
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRP C-reactive protein, pentraxin-related
CSF1R colony stimulating factor 1 receptor
CUL3 cullin 3
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DPY19L1 dpy-19-like 1 (C. elegans)
EGFR epidermal growth factor receptor
EPHA7 EPH receptor A7
FAM182A family with sequence similarity 182, member A
FILIP1L filamin A interacting protein 1-like
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLRA3 glycine receptor, alpha 3
GRM7 glutamate receptor, metabotropic 7
HHAT hedgehog acyltransferase
HOMER3 homer scaffolding protein 3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL6ST interleukin 6 signal transducer
ING1 inhibitor of growth family, member 1
KERA keratocan
KLF12 Kruppel-like factor 12
KLF4 Kruppel-like factor 4 (gut)
KLHL18 kelch-like family member 18
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPIN1 lipin 1
LRP4 low density lipoprotein receptor-related protein 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MET MET proto-oncogene, receptor tyrosine kinase
MORC1 MORC family CW-type zinc finger 1
NEFM neurofilament, medium polypeptide
NEK9 NIMA-related kinase 9
NOD1 nucleotide-binding oligomerization domain containing 1
NPC1 Niemann-Pick disease, type C1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRP1 neuropilin 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHB13 protocadherin beta 13
PCDHB3 protocadherin beta 3
PCNX pecanex homolog (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLSCR2 phospholipid scramblase 2
PLXNB3 plexin B3
PPARA peroxisome proliferator-activated receptor alpha
PVR poliovirus receptor
RAB6A RAB6A, member RAS oncogene family
RUNDC3A RUN domain containing 3A
SBNO1 strawberry notch homolog 1 (Drosophila)
SCN11A sodium channel, voltage gated, type XI alpha subunit
SENP7 SUMO1/sentrin specific peptidase 7
SEPP1 selenoprotein P, plasma, 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SOS2 son of sevenless homolog 2 (Drosophila)
SPANXC SPANX family, member C
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRSF5 serine/arginine-rich splicing factor 5
SSX1 synovial sarcoma, X breakpoint 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK17B serine/threonine kinase 17b
STX7 syntaxin 7
SYCP2 synaptonemal complex protein 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D22B TBC1 domain family, member 22B
TBC1D30 TBC1 domain family, member 30
TBX6 T-box 6
TFDP3 transcription factor Dp family, member 3
TFEB transcription factor EB
TLK1 tousled-like kinase 1
TLN2 talin 2
TRIM22 tripartite motif containing 22
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TSPAN31 tetraspanin 31
TXNRD3 thioredoxin reductase 3
UBA6 ubiquitin-like modifier activating enzyme 6
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
ZFHX2 zinc finger homeobox 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF155 zinc finger protein 155
ZNF34 zinc finger protein 34

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM2 ADAM metallopeptidase domain 2
ADAM23 ADAM metallopeptidase domain 23
AGMAT agmatine ureohydrolase (agmatinase)
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
ARL14 ADP-ribosylation factor-like 14
ARMCX4 armadillo repeat containing, X-linked 4
BDKRB1 bradykinin receptor B1
CA9 carbonic anhydrase IX
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CEL carboxyl ester lipase
CIDEB cell death-inducing DFFA-like effector b
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNN1 calponin 1, basic, smooth muscle
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRISP2 cysteine-rich secretory protein 2
CYSLTR1 cysteinyl leukotriene receptor 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND2D DENN/MADD domain containing 2D
ELMO3 engulfment and cell motility 3
EPHA4 EPH receptor A4
ETNK2 ethanolamine kinase 2
FAM120C family with sequence similarity 120C
FGF23 fibroblast growth factor 23
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ21369 uncharacterized protein FLJ21369
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
GAS8 growth arrest-specific 8
GLS2 glutaminase 2 (liver, mitochondrial)
GPR1 G protein-coupled receptor 1
GPR27 G protein-coupled receptor 27
GREB1L growth regulation by estrogen in breast cancer-like
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HOOK1 hook microtubule-tethering protein 1
HOXA2 homeobox A2
IDI2-AS1 IDI2 antisense RNA 1
IL17RB interleukin 17 receptor B
IL6 interleukin 6
INF2 inverted formin, FH2 and WH2 domain containing
IQSEC2 IQ motif and Sec7 domain 2
ITPKA inositol-trisphosphate 3-kinase A
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIAA1456 KIAA1456
KIRREL kin of IRRE like (Drosophila)
KPTN kaptin (actin binding protein)
KRT20 keratin 20, type I
LOC100127972 uncharacterized LOC100127972
MFSD11 major facilitator superfamily domain containing 11
MGP matrix Gla protein
MRPL41 mitochondrial ribosomal protein L41
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NPFFR1 neuropeptide FF receptor 1
NT5M 5',3'-nucleotidase, mitochondrial
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC8 placenta-specific 8
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRB3 proline-rich protein BstNI subfamily 3
PRR4 proline rich 4 (lacrimal)
PRSS8 protease, serine, 8
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF2 ring finger protein 2
RUNDC3B RUN domain containing 3B
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERGEF secretion regulating guanine nucleotide exchange factor
SKA1 spindle and kinetochore associated complex subunit 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SP1 Sp1 transcription factor
SSBP3 single stranded DNA binding protein 3
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCEAL2 transcription elongation factor A (SII)-like 2
TEX40 testis expressed 40
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
WNT7A wingless-type MMTV integration site family, member 7A
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF446 zinc finger protein 446
ZNF671 zinc finger protein 671