pentetic acid-3049 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pentetic acid-3049 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
AASS aminoadipate-semialdehyde synthase
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
AMACR alpha-methylacyl-CoA racemase
APOA1 apolipoprotein A-I
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CALML3 calmodulin-like 3
CCDC40 coiled-coil domain containing 40
CCL21 chemokine (C-C motif) ligand 21
CD24 CD24 molecule
CD5 CD5 molecule
CD96 CD96 molecule
CHRM3 cholinergic receptor, muscarinic 3
COL5A2 collagen, type V, alpha 2
COL9A3 collagen, type IX, alpha 3
CPN2 carboxypeptidase N, polypeptide 2
CRABP2 cellular retinoic acid binding protein 2
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYHR1 cysteine/histidine-rich 1
DKKL1 dickkopf-like 1
DNAH3 dynein, axonemal, heavy chain 3
DPP4 dipeptidyl-peptidase 4
EDDM3B epididymal protein 3B
EPAS1 endothelial PAS domain protein 1
ERBB3 erb-b2 receptor tyrosine kinase 3
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXO40 F-box protein 40
FGFR3 fibroblast growth factor receptor 3
FOXE1 forkhead box E1
FXYD3 FXYD domain containing ion transport regulator 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GJA9 gap junction protein, alpha 9, 59kDa
GNAS GNAS complex locus
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOXD13 homeobox D13
HPR haptoglobin-related protein
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IDS iduronate 2-sulfatase
IL26 interleukin 26
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLF5 Kruppel-like factor 5 (intestinal)
KLHL22 kelch-like family member 22
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRTAP1-3 keratin associated protein 1-3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMOD1 leiomodin 1 (smooth muscle)
LSR lipolysis stimulated lipoprotein receptor
MED16 mediator complex subunit 16
MPDZ multiple PDZ domain protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMUR1 neuromedin U receptor 1
NRAP nebulin-related anchoring protein
NRG1 neuregulin 1
NRXN2 neurexin 2
NUP188 nucleoporin 188kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PCDHB17P protocadherin beta 17 pseudogene
PCLO piccolo presynaptic cytomatrix protein
PKP3 plakophilin 3
PLCE1 phospholipase C, epsilon 1
PLN phospholamban
PLXNB3 plexin B3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PQBP1 polyglutamine binding protein 1
PRLR prolactin receptor
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRSS50 protease, serine, 50
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene
RPS6 ribosomal protein S6
RUFY3 RUN and FYVE domain containing 3
RUNDC3A RUN domain containing 3A
SEZ6L seizure related 6 homolog (mouse)-like
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOX10 SRY (sex determining region Y)-box 10
SPARCL1 SPARC-like 1 (hevin)
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SRPX2 sushi-repeat containing protein, X-linked 2
SYCE1L synaptonemal complex central element protein 1-like
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TIAM1 T-cell lymphoma invasion and metastasis 1
TRBC1 T cell receptor beta constant 1
TSHR thyroid stimulating hormone receptor
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UNC119 unc-119 homolog (C. elegans)
ZNF507 zinc finger protein 507

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARMCX4 armadillo repeat containing, X-linked 4
ARR3 arrestin 3, retinal (X-arrestin)
BBC3 BCL2 binding component 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BTBD18 BTB (POZ) domain containing 18
C5ORF45 chromosome 5 open reading frame 45
CCDC106 coiled-coil domain containing 106
CCDC186 coiled-coil domain containing 186
CD300C CD300c molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CFP complement factor properdin
CHMP6 charged multivesicular body protein 6
CLCN5 chloride channel, voltage-sensitive 5
CLGN calmegin
CPEB3 cytoplasmic polyadenylation element binding protein 3
DGKG diacylglycerol kinase, gamma 90kDa
DTX2 deltex 2, E3 ubiquitin ligase
ELAC1 elaC ribonuclease Z 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EMILIN2 elastin microfibril interfacer 2
ERCC4 excision repair cross-complementation group 4
FAM184A family with sequence similarity 184, member A
FAM53B family with sequence similarity 53, member B
FBXL7 F-box and leucine-rich repeat protein 7
FDXR ferredoxin reductase
FGF6 fibroblast growth factor 6
FKBP9 FK506 binding protein 9, 63 kDa
FOXO4 forkhead box O4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAREM GRB2 associated, regulator of MAPK1
GIF gastric intrinsic factor (vitamin B synthesis)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC7 histone deacetylase 7
HIST1H1B histone cluster 1, H1b
HIST1H2BJ histone cluster 1, H2bj
HOXA2 homeobox A2
HP haptoglobin
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL22 interleukin 22
IQSEC2 IQ motif and Sec7 domain 2
IRAK4 interleukin-1 receptor-associated kinase 4
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KL klotho
LIG4 ligase IV, DNA, ATP-dependent
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MED15 mediator complex subunit 15
MICA MHC class I polypeptide-related sequence A
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MUC6 mucin 6, oligomeric mucus/gel-forming
NDE1 nudE neurodevelopment protein 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOL10 nucleolar protein 10
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OCM2 oncomodulin 2
OXTR oxytocin receptor
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE7B phosphodiesterase 7B
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS21 protease, serine, 21 (testisin)
PSG4 pregnancy specific beta-1-glycoprotein 4
RIN2 Ras and Rab interactor 2
SCG5 secretogranin V
SH3BGR SH3 domain binding glutamate-rich protein
SH3PXD2A SH3 and PX domains 2A
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLAMF7 SLAM family member 7
SLC12A8 solute carrier family 12, member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATA2L spermatogenesis associated 2-like
SPHK1 sphingosine kinase 1
STARD13 StAR-related lipid transfer (START) domain containing 13
TESPA1 thymocyte expressed, positive selection associated 1
TEX15 testis expressed 15
TFDP3 transcription factor Dp family, member 3
THEM6 thioesterase superfamily member 6
TMEM242 transmembrane protein 242
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TONSL tonsoku-like, DNA repair protein
TRAF2 TNF receptor-associated factor 2
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM49 tripartite motif containing 49
TTC30A tetratricopeptide repeat domain 30A
TUFT1 tuftelin 1
ZNF10 zinc finger protein 10
ZNF219 zinc finger protein 219
ZNF76 zinc finger protein 76