pcg protein complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure. (Gene Ontology, GO_0031519)
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Genes

200 proteins co-occuring with the pcg protein complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PRC1 protein regulator of cytokinesis 1 2.87074
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.71262
BMI1 BMI1 proto-oncogene, polycomb ring finger 2.66472
SUZ12 SUZ12 polycomb repressive complex 2 subunit 2.20445
ASXL1 additional sex combs like transcriptional regulator 1 2.13768
RING1 ring finger protein 1 2.12531
PCGF2 polycomb group ring finger 2 1.90701
CBX7 chromobox homolog 7 1.79177
EED embryonic ectoderm development 1.7669
RNF2 ring finger protein 2 1.72244
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 1.64733
H3F3B H3 histone, family 3B (H3.3B) 1.64195
H3F3A H3 histone, family 3A 1.64195
CBX8 chromobox homolog 8 1.53049
RYBP RING1 and YY1 binding protein 1.44234
CBX4 chromobox homolog 4 1.4198
PHC1 polyhomeotic homolog 1 (Drosophila) 1.35978
CBX2 chromobox homolog 2 1.35266
MTF2 metal response element binding transcription factor 2 1.34283
JARID2 jumonji, AT rich interactive domain 2 1.30766
H2AFJ H2A histone family, member J 1.25864
HIST1H2AJ histone cluster 1, H2aj 1.25864
HIST1H2AD histone cluster 1, H2ad 1.25864
HIST1H2AH histone cluster 1, H2ah 1.25811
HIST1H2AM histone cluster 1, H2am 1.25811
HIST1H2AG histone cluster 1, H2ag 1.25653
YY1 YY1 transcription factor 1.25653
CBX6 chromobox homolog 6 1.25495
H2AFY2 H2A histone family, member Y2 1.2539
HIST1H2AB histone cluster 1, H2ab 1.25338
HIST1H2AE histone cluster 1, H2ae 1.25338
H2AFV H2A histone family, member V 1.25285
H2AFB1 H2A histone family, member B1 1.24865
H2AFB2 H2A histone family, member B2 1.24445
H2AFY H2A histone family, member Y 1.23975
SCML2 sex comb on midleg-like 2 (Drosophila) 1.23975
KDM2B lysine (K)-specific demethylase 2B 1.19057
L3MBTL2 l(3)mbt-like 2 (Drosophila) 1.17619
L3MBTL1 l(3)mbt-like 1 (Drosophila) 1.15518
PHF19 PHD finger protein 19 1.15313
PCGF1 polycomb group ring finger 1 1.14443
E2F6 E2F transcription factor 6 1.07106
PCGF6 polycomb group ring finger 6 1.05589
SFMBT1 Scm-like with four mbt domains 1 1.00251
HIST2H2AC histone cluster 2, H2ac 0.976619
HIST2H2AA4 histone cluster 2, H2aa4 0.976135
HIST2H2AA3 histone cluster 2, H2aa3 0.976135
MBTD1 mbt domain containing 1 0.97178
CDKN2A cyclin-dependent kinase inhibitor 2A 0.963107
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.941636
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 0.915309
AEBP2 AE binding protein 2 0.907855
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.79927
YAF2 YY1 associated factor 2 0.791022
HOXA9 homeobox A9 0.790564
KDM6A lysine (K)-specific demethylase 6A 0.769083
FOXK2 forkhead box K2 0.740515
ZNF484 zinc finger protein 484 0.700863
PHF1 PHD finger protein 1 0.699983
PHC2 polyhomeotic homolog 2 (Drosophila) 0.694709
KDM6B lysine (K)-specific demethylase 6B 0.690326
KDM5B lysine (K)-specific demethylase 5B 0.688576
HOXD4 homeobox D4 0.670725
ASXL3 additional sex combs like transcriptional regulator 3 0.655602
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.654741
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.65259
ASXL2 additional sex combs like transcriptional regulator 2 0.639289
NANOG Nanog homeobox 0.623504
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.617557
SSX1 synovial sarcoma, X breakpoint 1 0.585105
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.572994
HOXD11 homeobox D11 0.572162
MBD6 methyl-CpG binding domain protein 6 0.554732
RIPPLY3 ripply transcriptional repressor 3 0.553491
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.539883
KMT2A lysine (K)-specific methyltransferase 2A 0.533719
LPPR4 lipid phosphate phosphatase-related protein type 4 0.503506
L3MBTL3 l(3)mbt-like 3 (Drosophila) 0.502693
UIMC1 ubiquitin interaction motif containing 1 0.500664
HOXB9 homeobox B9 0.499042
SS18 synovial sarcoma translocation, chromosome 18 0.491348
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.479647
BCOR BCL6 corepressor 0.451631
CDX4 caudal type homeobox 4 0.448054
KIF20B kinesin family member 20B 0.446862
BRWD1 bromodomain and WD repeat domain containing 1 0.434591
FAM170A family with sequence similarity 170, member A 0.426318
SOX2 SRY (sex determining region Y)-box 2 0.420428
TRIM27 tripartite motif containing 27 0.419252
HOXD9 homeobox D9 0.414555
NMRAL1 NmrA-like family domain containing 1 0.413382
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.412992
USP37 ubiquitin specific peptidase 37 0.403248
PARK2 parkin RBR E3 ubiquitin protein ligase 0.396648
SSX4 synovial sarcoma, X breakpoint 4 0.393549
SSX4B synovial sarcoma, X breakpoint 4B 0.393549
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.392388
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.391615
PHC3 polyhomeotic homolog 3 (Drosophila) 0.388137
EN2 engrailed homeobox 2 0.386208
SLBP stem-loop binding protein 0.384665
ZFP42 ZFP42 zinc finger protein 0.382739
HOXD12 homeobox D12 0.381199
NFRKB nuclear factor related to kappaB binding protein 0.378507
GATA6 GATA binding protein 6 0.378507
PIAS2 protein inhibitor of activated STAT, 2 0.373899
BRCA1 breast cancer 1, early onset 0.355563
USP11 ubiquitin specific peptidase 11 0.355563
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.354042
DOT1L DOT1-like histone H3K79 methyltransferase 0.350243
PRMT8 protein arginine methyltransferase 8 0.339639
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 0.335487
CDYL chromodomain protein, Y-like 0.323825
HDAC1 histone deacetylase 1 0.314091
SOX21 SRY (sex determining region Y)-box 21 0.301425
HACL1 2-hydroxyacyl-CoA lyase 1 0.294378
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.288091
RUVBL2 RuvB-like AAA ATPase 2 0.287352
ENSA endosulfine alpha 0.279245
MIR214 microRNA 214 0.264946
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.263485
KMT2B lysine (K)-specific methyltransferase 2B 0.260202
FAXDC2 fatty acid hydroxylase domain containing 2 0.259473
HOXB8 homeobox B8 0.252202
SETDB1 SET domain, bifurcated 1 0.250751
LGALS4 lectin, galactoside-binding, soluble, 4 0.250389
MAGEA1 melanoma antigen family A1 0.246046
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 0.243158
CASP8AP2 caspase 8 associated protein 2 0.242797
KAT6A K(lysine) acetyltransferase 6A 0.23776
PARP3 poly (ADP-ribose) polymerase family, member 3 0.232386
MOV10 Mov10 RISC complex RNA helicase 0.230245
HIST1H4H histone cluster 1, H4h 0.230245
HIST1H4I histone cluster 1, H4i 0.230245
PBX1 pre-B-cell leukemia homeobox 1 0.230245
HIST1H4E histone cluster 1, H4e 0.230245
HIST1H4J histone cluster 1, H4j 0.230245
HIST1H4K histone cluster 1, H4k 0.230245
HIST1H4D histone cluster 1, H4d 0.230245
HIST1H4A histone cluster 1, H4a 0.230245
HIST1H4B histone cluster 1, H4b 0.230245
HIST1H4C histone cluster 1, H4c 0.230245
HIST2H4B histone cluster 2, H4b 0.230245
HIST1H4F histone cluster 1, H4f 0.229888
HIST1H4L histone cluster 1, H4l 0.229888
HIST2H4A histone cluster 2, H4a 0.229888
HIST4H4 histone cluster 4, H4 0.229888
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.228464
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.226686
SOX17 SRY (sex determining region Y)-box 17 0.222083
RBBP4 retinoblastoma binding protein 4 0.221378
MIR22 microRNA 22 0.205059
BCL6 B-cell CLL/lymphoma 6 0.200663
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.19733
SPOP speckle-type POZ protein 0.193394
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.1921
KLF4 Kruppel-like factor 4 (gut) 0.18796
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.182723
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.177439
SIX4 SIX homeobox 4 0.168847
HDAC9 histone deacetylase 9 0.159658
CHD4 chromodomain helicase DNA binding protein 4 0.158882
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.15776
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.157039
ADRM1 adhesion regulating molecule 1 0.140515
SIN3A SIN3 transcription regulator family member A 0.137353
TRIM10 tripartite motif containing 10 0.135716
UBN1 ubinuclein 1 0.135617
TRIM26 tripartite motif containing 26 0.1356
TRIM15 tripartite motif containing 15 0.135381
SUMO3 small ubiquitin-like modifier 3 0.134999
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.134919
SUMO2 small ubiquitin-like modifier 2 0.134621
HOXB1 homeobox B1 0.134565
TBX3 T-box 3 0.134054
STAG3 stromal antigen 3 0.133966
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.133678
ASCL2 achaete-scute family bHLH transcription factor 2 0.131193
ETV6 ets variant 6 0.130817
TWIST1 twist family bHLH transcription factor 1 0.130538
HOXC13 homeobox C13 0.130375
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.130251
VIL1 villin 1 0.129209
STRA8 stimulated by retinoic acid 8 0.127176
EGLN2 egl-9 family hypoxia-inducible factor 2 0.127122
SETD7 SET domain containing (lysine methyltransferase) 7 0.127012
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.125175
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.124806
DDB1 damage-specific DNA binding protein 1, 127kDa 0.124198
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.124058
HDAC7 histone deacetylase 7 0.123894
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 0.123822
MNX1 motor neuron and pancreas homeobox 1 0.123312
MPL MPL proto-oncogene, thrombopoietin receptor 0.123062
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.122521
PRMT2 protein arginine methyltransferase 2 0.122201
STMN1 stathmin 1 0.12179
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.121366
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.120899
STAT5B signal transducer and activator of transcription 5B 0.12081