pattern recognition receptor signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells. (Gene Ontology, GO_0002221)
External Link http://amigo.geneontology.org/amigo/term/GO:0002221
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Genes

140 genes participating in the pattern recognition receptor signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
BCL10 B-cell CLL/lymphoma 10
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BTK Bruton agammaglobulinemia tyrosine kinase
CARD9 caspase recruitment domain family, member 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD14 CD14 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD86 CD86 molecule
CDK1 cyclin-dependent kinase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC7A C-type lectin domain family 7, member A
CNPY3 canopy FGF signaling regulator 3
COLEC12 collectin sub-family member 12
CREB1 cAMP responsive element binding protein 1
CTSB cathepsin B
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DMBT1 deleted in malignant brain tumors 1
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
ELK1 ELK1, member of ETS oncogene family
FADD Fas (TNFRSF6)-associated via death domain
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FFAR2 free fatty acid receptor 2
FOS FBJ murine osteosarcoma viral oncogene homolog
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFIH1 interferon induced with helicase C domain 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ITCH itchy E3 ubiquitin protein ligase
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
LBP lipopolysaccharide binding protein
LGMN legumain
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LY96 lymphocyte antigen 96
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MAVS mitochondrial antiviral signaling protein
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
OTULIN OTU deubiquitinase with linear linkage specificity
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKCE protein kinase C, epsilon
REG3G regenerating islet-derived 3 gamma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFTN1 raftlin, lipid raft linker 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RPS27A ribosomal protein S27a
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A14 S100 calcium binding protein A14
SARM1 sterile alpha and TIR motif containing 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TNIP3 TNFAIP3 interacting protein 3
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIL TLR4 interactor with leucine-rich repeats
TRIM5 tripartite motif containing 5
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2N ubiquitin-conjugating enzyme E2N
UNC93B1 unc-93 homolog B1 (C. elegans)