paroxetine-4556 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


194 genes differentially expressed following the paroxetine-4556 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADTRP androgen-dependent TFPI-regulating protein
C4BPA complement component 4 binding protein, alpha
C5AR1 complement component 5a receptor 1
C6ORF10 chromosome 6 open reading frame 10
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC64 coiled-coil domain containing 64
CCL24 chemokine (C-C motif) ligand 24
CD7 CD7 molecule
CD80 CD80 molecule
CNN1 calponin 1, basic, smooth muscle
COMMD4 COMM domain containing 4
CPT1A carnitine palmitoyltransferase 1A (liver)
CSHL1 chorionic somatomammotropin hormone-like 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYTH4 cytohesin 4
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD2 dopamine receptor D2
DSTYK dual serine/threonine and tyrosine protein kinase
FGFR2 fibroblast growth factor receptor 2
FH fumarate hydratase
FYB FYN binding protein
GAS7 growth arrest-specific 7
GHRHR growth hormone releasing hormone receptor
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR22 G protein-coupled receptor 22
HIST1H2BM histone cluster 1, H2bm
HOXD13 homeobox D13
HOXD3 homeobox D3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYAL4 hyaluronoglucosaminidase 4
IFNA14 interferon, alpha 14
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL12RB1 interleukin 12 receptor, beta 1
IL2 interleukin 2
ING4 inhibitor of growth family, member 4
KIF5C kinesin family member 5C
KLK2 kallikrein-related peptidase 2
KLK7 kallikrein-related peptidase 7
KRT14 keratin 14, type I
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
METTL7A methyltransferase like 7A
MKL1 megakaryoblastic leukemia (translocation) 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRPL41 mitochondrial ribosomal protein L41
MTUS1 microtubule associated tumor suppressor 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOZ3 myozenin 3
NCR2 natural cytotoxicity triggering receptor 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NPY2R neuropeptide Y receptor Y2
NTF3 neurotrophin 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OCM2 oncomodulin 2
OLFM1 olfactomedin 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PASK PAS domain containing serine/threonine kinase
PAX8 paired box 8
PBOV1 prostate and breast cancer overexpressed 1
PCDHB12 protocadherin beta 12
PDCD2 programmed cell death 2
PDE10A phosphodiesterase 10A
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PENK proenkephalin
PGLYRP4 peptidoglycan recognition protein 4
PLA2G5 phospholipase A2, group V
PLK4 polo-like kinase 4
PLP1 proteolipid protein 1
POMT2 protein-O-mannosyltransferase 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PSORS1C1 psoriasis susceptibility 1 candidate 1
PYY peptide YY
RAD23B RAD23 homolog B (S. cerevisiae)
RBMS2 RNA binding motif, single stranded interacting protein 2
RFXAP regulatory factor X-associated protein
S100A5 S100 calcium binding protein A5
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SULF1 sulfatase 1
TFR2 transferrin receptor 2
TLR4 toll-like receptor 4
TMEM212 transmembrane protein 212
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
WDR59 WD repeat domain 59
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZFPL1 zinc finger protein-like 1
ZNF518A zinc finger protein 518A
ZNF749 zinc finger protein 749

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AEN apoptosis enhancing nuclease
ARHGAP10 Rho GTPase activating protein 10
ARHGAP12 Rho GTPase activating protein 12
ATAD2B ATPase family, AAA domain containing 2B
C4ORF19 chromosome 4 open reading frame 19
C8ORF60 chromosome 8 open reading frame 60
CDK9 cyclin-dependent kinase 9
CDT1 chromatin licensing and DNA replication factor 1
CEP70 centrosomal protein 70kDa
CFAP44 cilia and flagella associated protein 44
CHD3 chromodomain helicase DNA binding protein 3
CRABP2 cellular retinoic acid binding protein 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUEDC1 CUE domain containing 1
DBR1 debranching RNA lariats 1
DNAL4 dynein, axonemal, light chain 4
DOLPP1 dolichyldiphosphatase 1
EFNA3 ephrin-A3
EGR2 early growth response 2
ELP3 elongator acetyltransferase complex subunit 3
ERF Ets2 repressor factor
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM53B family with sequence similarity 53, member B
FANCC Fanconi anemia, complementation group C
FOXC1 forkhead box C1
FOXK2 forkhead box K2
FPGS folylpolyglutamate synthase
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GMIP GEM interacting protein
GUSBP3 glucuronidase, beta pseudogene 3
HELZ helicase with zinc finger
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFI44L interferon-induced protein 44-like
IGSF3 immunoglobulin superfamily, member 3
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
JMJD4 jumonji domain containing 4
KIAA0319L KIAA0319-like
KIAA1462 KIAA1462
KPTN kaptin (actin binding protein)
LBR lamin B receptor
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC8E leucine rich repeat containing 8 family, member E
LZTR1 leucine-zipper-like transcription regulator 1
MOXD1 monooxygenase, DBH-like 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MST1R macrophage stimulating 1 receptor
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRTN neurturin
NTSR1 neurotensin receptor 1 (high affinity)
PACS1 phosphofurin acidic cluster sorting protein 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX26 peroxisomal biogenesis factor 26
PFAS phosphoribosylformylglycinamidine synthase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIEZO1 piezo-type mechanosensitive ion channel component 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PROSER1 proline and serine rich 1
PSKH1 protein serine kinase H1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF123 ring finger protein 123
RPP25 ribonuclease P/MRP 25kDa subunit
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SECISBP2 SECIS binding protein 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMAP1 small ArfGAP 1
SNX16 sorting nexin 16
STK16 serine/threonine kinase 16
SUN2 Sad1 and UNC84 domain containing 2
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCTN1 tectonic family member 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM53 transmembrane protein 53
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOR4A torsin family 4, member A
TRIM21 tripartite motif containing 21
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
ULK1 unc-51 like autophagy activating kinase 1
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
ZBTB44 zinc finger and BTB domain containing 44
ZHX2 zinc fingers and homeoboxes 2
ZNF264 zinc finger protein 264
ZNF276 zinc finger protein 276
ZNF358 zinc finger protein 358