pargyline-7016 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the pargyline-7016 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM19 ADAM metallopeptidase domain 19
AK2 adenylate kinase 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAIAP2 BAI1-associated protein 2
BIN1 bridging integrator 1
C1ORF61 chromosome 1 open reading frame 61
C2ORF68 chromosome 2 open reading frame 68
CAMTA1 calmodulin binding transcription activator 1
CARD9 caspase recruitment domain family, member 9
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKE diacylglycerol kinase, epsilon 64kDa
DOC2A double C2-like domains, alpha
DOCK6 dedicator of cytokinesis 6
DVL3 dishevelled segment polarity protein 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAM65A family with sequence similarity 65, member A
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLP1R glucagon-like peptide 1 receptor
GLS2 glutaminase 2 (liver, mitochondrial)
GOSR2 golgi SNAP receptor complex member 2
GPATCH4 G patch domain containing 4
GPC3 glypican 3
GRIK5 glutamate receptor, ionotropic, kainate 5
GTPBP4 GTP binding protein 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ING1 inhibitor of growth family, member 1
IRF9 interferon regulatory factor 9
KAZN kazrin, periplakin interacting protein
LARP6 La ribonucleoprotein domain family, member 6
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRRC40 leucine rich repeat containing 40
MCM3AP minichromosome maintenance complex component 3 associated protein
MED15 mediator complex subunit 15
MUC3A mucin 3A, cell surface associated
NF1 neurofibromin 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOX1 NADPH oxidase 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRF1 nuclear respiratory factor 1
OASL 2'-5'-oligoadenylate synthetase-like
ORAI2 ORAI calcium release-activated calcium modulator 2
PACS1 phosphofurin acidic cluster sorting protein 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANBP3 RAN binding protein 3
RASAL2 RAS protein activator like 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS9 regulator of G-protein signaling 9
RNF19B ring finger protein 19B
RPH3A rabphilin 3A
SASH1 SAM and SH3 domain containing 1
SCARA3 scavenger receptor class A, member 3
SCN2B sodium channel, voltage gated, type II beta subunit
SETD1A SET domain containing 1A
SIK2 salt-inducible kinase 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SOWAHC sosondowah ankyrin repeat domain family member C
SOX13 SRY (sex determining region Y)-box 13
SP100 SP100 nuclear antigen
SRPX sushi-repeat containing protein, X-linked
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SUN2 Sad1 and UNC84 domain containing 2
SYT12 synaptotagmin XII
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TGFB2 transforming growth factor, beta 2
TLE4 transducin-like enhancer of split 4
TMEM144 transmembrane protein 144
TMEM51 transmembrane protein 51
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
VWA5A von Willebrand factor A domain containing 5A
WSCD1 WSC domain containing 1
XAF1 XIAP associated factor 1
ZNF16 zinc finger protein 16
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF492 zinc finger protein 492
ZNF573 zinc finger protein 573
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARRB2 arrestin, beta 2
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AUH AU RNA binding protein/enoyl-CoA hydratase
BAK1 BCL2-antagonist/killer 1
BCAS1 breast carcinoma amplified sequence 1
BCORL1 BCL6 corepressor-like 1
BPGM 2,3-bisphosphoglycerate mutase
C1ORF35 chromosome 1 open reading frame 35
C5 complement component 5
CALCOCO1 calcium binding and coiled-coil domain 1
CCNO cyclin O
CDR2L cerebellar degeneration-related protein 2-like
CIDEC cell death-inducing DFFA-like effector c
CTAGE9 CTAGE family, member 9
CXORF56 chromosome X open reading frame 56
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DET1 de-etiolated homolog 1 (Arabidopsis)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DSCAM Down syndrome cell adhesion molecule
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ELMO3 engulfment and cell motility 3
EPHA2 EPH receptor A2
FAM188A family with sequence similarity 188, member A
FKBP5 FK506 binding protein 5
FOSL1 FOS-like antigen 1
GALT galactose-1-phosphate uridylyltransferase
GPR87 G protein-coupled receptor 87
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AG histone cluster 1, H2ag
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IRAK4 interleukin-1 receptor-associated kinase 4
KRBOX4 KRAB box domain containing 4
LIN7B lin-7 homolog B (C. elegans)
LMCD1 LIM and cysteine-rich domains 1
LRP3 low density lipoprotein receptor-related protein 3
LRRC20 leucine rich repeat containing 20
MAP9 microtubule-associated protein 9
METTL4 methyltransferase like 4
MFSD12 major facilitator superfamily domain containing 12
MITF microphthalmia-associated transcription factor
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NECAP2 NECAP endocytosis associated 2
NES nestin
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRGN neurogranin (protein kinase C substrate, RC3)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
ORAI3 ORAI calcium release-activated calcium modulator 3
PANX1 pannexin 1
PARD6A par-6 family cell polarity regulator alpha
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POLI polymerase (DNA directed) iota
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RANGRF RAN guanine nucleotide release factor
RBM23 RNA binding motif protein 23
RECQL4 RecQ protein-like 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RWDD3 RWD domain containing 3
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC12A8 solute carrier family 12, member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A40 solute carrier family 25, member 40
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMA4 glucuronidase, beta pseudogene
SNHG20 small nucleolar RNA host gene 20
SPIDR scaffolding protein involved in DNA repair
TM7SF3 transmembrane 7 superfamily member 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM2 transmembrane protein 2
TNRC6B trinucleotide repeat containing 6B
TRAPPC13 trafficking protein particle complex 13
TWF2 twinfilin actin binding protein 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
YEATS4 YEATS domain containing 4
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP30 ZFP30 zinc finger protein
ZMAT3 zinc finger, matrin-type 3
ZMYM3 zinc finger, MYM-type 3
ZNF248 zinc finger protein 248
ZNF276 zinc finger protein 276
ZNF35 zinc finger protein 35
ZNF767P zinc finger family member 767, pseudogene