pargyline-2102 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the pargyline-2102 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADTRP androgen-dependent TFPI-regulating protein
ALK anaplastic lymphoma receptor tyrosine kinase
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP22 Rho GTPase activating protein 22
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
BFSP1 beaded filament structural protein 1, filensin
BMP1 bone morphogenetic protein 1
BTG3 BTG family, member 3
C1QL1 complement component 1, q subcomponent-like 1
CD24 CD24 molecule
CEP164 centrosomal protein 164kDa
COL10A1 collagen, type X, alpha 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOC2A double C2-like domains, alpha
DUOX2 dual oxidase 2
EFHC2 EF-hand domain (C-terminal) containing 2
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPOR erythropoietin receptor
ESRRG estrogen-related receptor gamma
EVI5 ecotropic viral integration site 5
EXOC6B exocyst complex component 6B
FKBP8 FK506 binding protein 8, 38kDa
FNDC4 fibronectin type III domain containing 4
GAL3ST4 galactose-3-O-sulfotransferase 4
GK glycerol kinase
GMEB1 glucocorticoid modulatory element binding protein 1
GRM1 glutamate receptor, metabotropic 1
HIF3A hypoxia inducible factor 3, alpha subunit
HIST1H3G histone cluster 1, H3g
HNF1B HNF1 homeobox B
HOXA4 homeobox A4
HOXB5 homeobox B5
HRK harakiri, BCL2 interacting protein
IFI6 interferon, alpha-inducible protein 6
IFNA17 interferon, alpha 17
IL22 interleukin 22
INADL InaD-like (Drosophila)
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIAA1644 KIAA1644
KIRREL kin of IRRE like (Drosophila)
LARGE like-glycosyltransferase
MAP1A microtubule-associated protein 1A
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCC mutated in colorectal cancers
MINK1 misshapen-like kinase 1
NOL10 nucleolar protein 10
NOP14-AS1 NOP14 antisense RNA 1
NUP160 nucleoporin 160kDa
OLIG2 oligodendrocyte lineage transcription factor 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAX9 paired box 9
PHTF2 putative homeodomain transcription factor 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPP1R7 protein phosphatase 1, regulatory subunit 7
PTPRH protein tyrosine phosphatase, receptor type, H
PWAR5 Prader Willi/Angelman region RNA 5
QKI QKI, KH domain containing, RNA binding
RAD51B RAD51 paralog B
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBL2 retinoblastoma-like 2
REST RE1-silencing transcription factor
RGS4 regulator of G-protein signaling 4
SFTPB surfactant protein B
SIDT2 SID1 transmembrane family, member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD5 SMAD family member 5
SOX12 SRY (sex determining region Y)-box 12
SOX13 SRY (sex determining region Y)-box 13
SP100 SP100 nuclear antigen
STS steroid sulfatase (microsomal), isozyme S
STX7 syntaxin 7
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX6 T-box 6
TDRD3 tudor domain containing 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTBK2 tau tubulin kinase 2
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UNC93A unc-93 homolog A (C. elegans)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VWA8 von Willebrand factor A domain containing 8
WDFY3 WD repeat and FYVE domain containing 3
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZMYM5 zinc finger, MYM-type 5
ZNF484 zinc finger protein 484
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANGPTL4 angiopoietin-like 4
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAS3 breast carcinoma amplified sequence 3
BCL9 B-cell CLL/lymphoma 9
BICD1 bicaudal D homolog 1 (Drosophila)
CAPN15 calpain 15
CAPN5 calpain 5
CBR4 carbonyl reductase 4
CCDC176 coiled-coil domain containing 176
CDK3 cyclin-dependent kinase 3
CEP131 centrosomal protein 131kDa
CFD complement factor D (adipsin)
CLDN15 claudin 15
CLIC3 chloride intracellular channel 3
CLIP4 CAP-GLY domain containing linker protein family, member 4
COBL cordon-bleu WH2 repeat protein
CRABP2 cellular retinoic acid binding protein 2
CUL9 cullin 9
CUTC cutC copper transporter
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF10 DDB1 and CUL4 associated factor 10
DMTN dematin actin binding protein
EXOC3 exocyst complex component 3
FA2H fatty acid 2-hydroxylase
FBXL15 F-box and leucine-rich repeat protein 15
FLCN folliculin
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GID4 GID complex subunit 4
HIRA histone cell cycle regulator
HIST1H3B histone cluster 1, H3b
IFI35 interferon-induced protein 35
IQCG IQ motif containing G
IRAK4 interleukin-1 receptor-associated kinase 4
KIAA0753 KIAA0753
KLHL36 kelch-like family member 36
LIN7B lin-7 homolog B (C. elegans)
LRRC14 leucine rich repeat containing 14
MCTP2 multiple C2 domains, transmembrane 2
MFSD11 major facilitator superfamily domain containing 11
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXRA8 matrix-remodelling associated 8
MYO19 myosin XIX
NISCH nischarin
NPR3 natriuretic peptide receptor 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEX26 peroxisomal biogenesis factor 26
PIBF1 progesterone immunomodulatory binding factor 1
PID1 phosphotyrosine interaction domain containing 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRAME preferentially expressed antigen in melanoma
RAB17 RAB17, member RAS oncogene family
RAB20 RAB20, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RANBP17 RAN binding protein 17
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUSC2 RUN and SH3 domain containing 2
SCEL sciellin
SH3BGR SH3 domain binding glutamate-rich protein
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNHG20 small nucleolar RNA host gene 20
SPAG4 sperm associated antigen 4
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBC1D17 TBC1 domain family, member 17
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TH tyrosine hydroxylase
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TKFC triokinase/FMN cyclase
TMCC2 transmembrane and coiled-coil domain family 2
TMEM120B transmembrane protein 120B
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA3C tubulin, alpha 3c
UBIAD1 UbiA prenyltransferase domain containing 1
WNT10B wingless-type MMTV integration site family, member 10B
WRAP73 WD repeat containing, antisense to TP73
XYLT2 xylosyltransferase II
ZBTB25 zinc finger and BTB domain containing 25
ZFP36 ZFP36 ring finger protein
ZNF107 zinc finger protein 107
ZNF189 zinc finger protein 189
ZNF35 zinc finger protein 35
ZNF415 zinc finger protein 415
ZNF692 zinc finger protein 692
ZNF701 zinc finger protein 701
ZNF816 zinc finger protein 816
ZNF84 zinc finger protein 84