parbendazole-3881 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the parbendazole-3881 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AJAP1 adherens junctions associated protein 1
AMH anti-Mullerian hormone
ANGPTL4 angiopoietin-like 4
APAF1 apoptotic peptidase activating factor 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ART1 ADP-ribosyltransferase 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF1 chromosome 14 open reading frame 1
C1QB complement component 1, q subcomponent, B chain
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD209 CD209 molecule
CDA cytidine deaminase
CDC25C cell division cycle 25C
CDC42 cell division cycle 42
CDHR1 cadherin-related family member 1
CELF2 CUGBP, Elav-like family member 2
CNTNAP1 contactin associated protein 1
COL6A3 collagen, type VI, alpha 3
CRTC1 CREB regulated transcription coactivator 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCLK1 doublecortin-like kinase 1
DOCK9 dedicator of cytokinesis 9
EFNA5 ephrin-A5
EML2 echinoderm microtubule associated protein like 2
EPAS1 endothelial PAS domain protein 1
EPHB2 EPH receptor B2
FGFR3 fibroblast growth factor receptor 3
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GDF5 growth differentiation factor 5
GK2 glycerol kinase 2
GPR182 G protein-coupled receptor 182
GPR35 G protein-coupled receptor 35
GRK5 G protein-coupled receptor kinase 5
HRG histidine-rich glycoprotein
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IFNA17 interferon, alpha 17
IL10RA interleukin 10 receptor, alpha
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB6 integrin, beta 6
KDM4B lysine (K)-specific demethylase 4B
KHSRP KH-type splicing regulatory protein
KIAA1024 KIAA1024
KRT8 keratin 8, type II
MAGEA3 melanoma antigen family A3
MMP11 matrix metallopeptidase 11
MT1E metallothionein 1E
MTMR7 myotubularin related protein 7
MTSS1 metastasis suppressor 1
MXRA5 matrix-remodelling associated 5
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NOX1 NADPH oxidase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NYX nyctalopin
PCDH11Y protocadherin 11 Y-linked
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE4C phosphodiesterase 4C, cAMP-specific
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDLIM5 PDZ and LIM domain 5
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLLP plasmolipin
POFUT1 protein O-fucosyltransferase 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRUNE2 prune homolog 2 (Drosophila)
PSCA prostate stem cell antigen
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPL23AP53 ribosomal protein L23a pseudogene 53
RPL7 ribosomal protein L7
RUFY3 RUN and FYVE domain containing 3
RUNX3 runt-related transcription factor 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
STAT2 signal transducer and activator of transcription 2, 113kDa
STC1 stanniocalcin 1
SUN1 Sad1 and UNC84 domain containing 1
TIMP3 TIMP metallopeptidase inhibitor 3
TJAP1 tight junction associated protein 1 (peripheral)
TLK1 tousled-like kinase 1
TMOD1 tropomodulin 1
TMPRSS4 transmembrane protease, serine 4
TPM3 tropomyosin 3
TRIB2 tribbles pseudokinase 2
TTLL7 tubulin tyrosine ligase-like family member 7
TTPA tocopherol (alpha) transfer protein
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VTN vitronectin

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C3 complement component 3
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPN5 calpain 5
CBX7 chromobox homolog 7
CD82 CD82 molecule
CD83 CD83 molecule
CHST10 carbohydrate sulfotransferase 10
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CSTA cystatin A (stefin A)
CTSF cathepsin F
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DPY19L1P1 DPY19L1 pseudogene 1
DUSP2 dual specificity phosphatase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV6 ets variant 6
FAM110B family with sequence similarity 110, member B
FBXL2 F-box and leucine-rich repeat protein 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FRK fyn-related Src family tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
GFI1 growth factor independent 1 transcription repressor
GID4 GID complex subunit 4
GMIP GEM interacting protein
GPR19 G protein-coupled receptor 19
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPX2 glutathione peroxidase 2
HIST1H2BG histone cluster 1, H2bg
HIST1H4F histone cluster 1, H4f
HOXA5 homeobox A5
HOXC10 homeobox C10
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IGFBP6 insulin-like growth factor binding protein 6
IL12RB1 interleukin 12 receptor, beta 1
IL17RA interleukin 17 receptor A
IL22 interleukin 22
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
LARP6 La ribonucleoprotein domain family, member 6
LINC00115 long intergenic non-protein coding RNA 115
LTBP2 latent transforming growth factor beta binding protein 2
MBNL3 muscleblind-like splicing regulator 3
MUC3A mucin 3A, cell surface associated
NPTX1 neuronal pentraxin I
NRSN2 neurensin 2
OVGP1 oviductal glycoprotein 1, 120kDa
PICK1 protein interacting with PRKCA 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCH pro-melanin-concentrating hormone
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB30 RAB30, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RECQL4 RecQ protein-like 4
RFXAP regulatory factor X-associated protein
RIBC2 RIB43A domain with coiled-coils 2
RIN1 Ras and Rab interactor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RPL23AP7 ribosomal protein L23a pseudogene 7
SIX1 SIX homeobox 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SPINK4 serine peptidase inhibitor, Kazal type 4
SRD5A3 steroid 5 alpha-reductase 3
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TSPAN9 tetraspanin 9
UBQLN4 ubiquilin 4
USP19 ubiquitin specific peptidase 19
WDR33 WD repeat domain 33
WDR5B WD repeat domain 5B
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF137P zinc finger protein 137, pseudogene
ZNF204P zinc finger protein 204, pseudogene
ZNF34 zinc finger protein 34
ZNF446 zinc finger protein 446
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76
ZNF816 zinc finger protein 816