parbendazole-3799 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the parbendazole-3799 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADGRB3 adhesion G protein-coupled receptor B3
ADORA1 adenosine A1 receptor
ADRB3 adrenoceptor beta 3
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANTXR1 anthrax toxin receptor 1
APAF1 apoptotic peptidase activating factor 1
APOF apolipoprotein F
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BMP5 bone morphogenetic protein 5
BTF3P11 basic transcription factor 3 pseudogene 11
C19ORF57 chromosome 19 open reading frame 57
C22ORF46 chromosome 22 open reading frame 46
CA9 carbonic anhydrase IX
CALCRL calcitonin receptor-like
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CD4 CD4 molecule
CD47 CD47 molecule
CFAP70 cilia and flagella associated protein 70
CLTCL1 clathrin, heavy chain-like 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CPNE6 copine VI (neuronal)
CREBZF CREB/ATF bZIP transcription factor
CRISP2 cysteine-rich secretory protein 2
CRTC1 CREB regulated transcription coactivator 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTSS cathepsin S
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DCHS1 dachsous cadherin-related 1
DMBT1 deleted in malignant brain tumors 1
DMPK dystrophia myotonica-protein kinase
DNAH7 dynein, axonemal, heavy chain 7
DUSP1 dual specificity phosphatase 1
EPYC epiphycan
GALC galactosylceramidase
GPR162 G protein-coupled receptor 162
GRAP GRB2-related adaptor protein
GREM2 gremlin 2, DAN family BMP antagonist
HEG1 heart development protein with EGF-like domains 1
HFE hemochromatosis
HHLA1 HERV-H LTR-associating 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
ICA1 islet cell autoantigen 1, 69kDa
IMPG2 interphotoreceptor matrix proteoglycan 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUND jun D proto-oncogene
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIF17 kinesin family member 17
KLHL22 kelch-like family member 22
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LUM lumican
MED25 mediator complex subunit 25
NEUROD6 neuronal differentiation 6
NNMT nicotinamide N-methyltransferase
NPTX1 neuronal pentraxin I
NRL neural retina leucine zipper
PALM paralemmin
PBX2 pre-B-cell leukemia homeobox 2
PDE9A phosphodiesterase 9A
PDLIM5 PDZ and LIM domain 5
PER1 period circadian clock 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PKNOX2 PBX/knotted 1 homeobox 2
POU5F1B POU class 5 homeobox 1B
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDM1 PR domain containing 1, with ZNF domain
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RHCE Rh blood group, CcEe antigens
RPL10 ribosomal protein L10
SCN1A sodium channel, voltage gated, type I alpha subunit
SIRPB1 signal-regulatory protein beta 1
SIRT5 sirtuin 5
SKIL SKI-like proto-oncogene
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SSTR1 somatostatin receptor 1
TAOK1 TAO kinase 1
TEX14 testis expressed 14
THTPA thiamine triphosphatase
TM4SF4 transmembrane 4 L six family member 4
TMPRSS6 transmembrane protease, serine 6
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TPM3 tropomyosin 3
TREM1 triggering receptor expressed on myeloid cells 1
TRIM48 tripartite motif containing 48
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTLL1 tubulin tyrosine ligase-like family member 1
UBE2I ubiquitin-conjugating enzyme E2I
WFDC1 WAP four-disulfide core domain 1
ZC3H13 zinc finger CCCH-type containing 13

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCY6 adenylate cyclase 6
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMDHD2 amidohydrolase domain containing 2
ANKH ANKH inorganic pyrophosphate transport regulator
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARID4A AT rich interactive domain 4A (RBP1-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BICC1 BicC family RNA binding protein 1
C17ORF53 chromosome 17 open reading frame 53
C5 complement component 5
CCNJ cyclin J
CD68 CD68 molecule
CDH7 cadherin 7, type 2
CDK3 cyclin-dependent kinase 3
CEP162 centrosomal protein 162kDa
CFAP45 cilia and flagella associated protein 45
CLSTN3 calsyntenin 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO1A coronin, actin binding protein, 1A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSRNP3 cysteine-serine-rich nuclear protein 3
CYB5R4 cytochrome b5 reductase 4
DENND4A DENN/MADD domain containing 4A
DGKE diacylglycerol kinase, epsilon 64kDa
DTX2 deltex 2, E3 ubiquitin ligase
EML4 echinoderm microtubule associated protein like 4
EXD3 exonuclease 3'-5' domain containing 3
FBRS fibrosin
FBXO31 F-box protein 31
FBXO46 F-box protein 46
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR21 G protein-coupled receptor 21
GRB7 growth factor receptor-bound protein 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AK histone cluster 1, H2ak
HIST1H2AM histone cluster 1, H2am
HIST1H3B histone cluster 1, H3b
HIST1H3H histone cluster 1, H3h
IFI6 interferon, alpha-inducible protein 6
IL11RA interleukin 11 receptor, alpha
IL12A interleukin 12A
KIAA0753 KIAA0753
KIAA0895 KIAA0895
KRT4 keratin 4, type II
LIFR leukemia inhibitory factor receptor alpha
LIN7B lin-7 homolog B (C. elegans)
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MANSC1 MANSC domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCTP1 multiple C2 domains, transmembrane 1
MMP2 matrix metallopeptidase 2
MNX1 motor neuron and pancreas homeobox 1
NOL10 nucleolar protein 10
NPY1R neuropeptide Y receptor Y1
OLFML2B olfactomedin-like 2B
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PALMD palmdelphin
PHC1 polyhomeotic homolog 1 (Drosophila)
PLSCR4 phospholipid scramblase 4
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PTGFR prostaglandin F receptor (FP)
PTPRS protein tyrosine phosphatase, receptor type, S
RASL11B RAS-like, family 11, member B
S1PR1 sphingosine-1-phosphate receptor 1
SCAMP5 secretory carrier membrane protein 5
SCIN scinderin
SEPP1 selenoprotein P, plasma, 1
SLAMF7 SLAM family member 7
SLC16A6 solute carrier family 16, member 6
SMAD7 SMAD family member 7
SPTBN2 spectrin, beta, non-erythrocytic 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TENM4 teneurin transmembrane protein 4
THRAP3 thyroid hormone receptor associated protein 3
TMEM180 transmembrane protein 180
TMEM209 transmembrane protein 209
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRDMT1 tRNA aspartic acid methyltransferase 1
TSC22D4 TSC22 domain family, member 4
TSNAXIP1 translin-associated factor X interacting protein 1
TUBA4B tubulin, alpha 4b
TXK TXK tyrosine kinase
UBTD1 ubiquitin domain containing 1
VGF VGF nerve growth factor inducible
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF37BP zinc finger protein 37B, pseudogene
ZNF529 zinc finger protein 529
ZNF629 zinc finger protein 629
ZNF639 zinc finger protein 639
ZNF671 zinc finger protein 671
ZNF747 zinc finger protein 747