paracetamol-3364 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the paracetamol-3364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
ANGPTL2 angiopoietin-like 2
ANPEP alanyl (membrane) aminopeptidase
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID5A AT rich interactive domain 5A (MRF1-like)
ARTN artemin
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAV3 caveolin 3
CCDC71 coiled-coil domain containing 71
CD48 CD48 molecule
CEND1 cell cycle exit and neuronal differentiation 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL16A1 collagen, type XVI, alpha 1
COMMD4 COMM domain containing 4
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DGCR8 DGCR8 microprocessor complex subunit
ECM1 extracellular matrix protein 1
EFNB3 ephrin-B3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FHL1 four and a half LIM domains 1
FKBP10 FK506 binding protein 10, 65 kDa
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GM2A GM2 ganglioside activator
GPSM3 G-protein signaling modulator 3
GZMK granzyme K (granzyme 3; tryptase II)
HOXA6 homeobox A6
HR hair growth associated
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
IZUMO4 IZUMO family member 4
KIF1C kinesin family member 1C
KLHL25 kelch-like family member 25
LAT2 linker for activation of T cells family, member 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MATN1 matrilin 1, cartilage matrix protein
MBD2 methyl-CpG binding domain protein 2
MEF2D myocyte enhancer factor 2D
MEGF6 multiple EGF-like-domains 6
MIR622 microRNA 622
MYO15B myosin XVB
MYOF myoferlin
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NEUROD6 neuronal differentiation 6
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRF1 nuclear respiratory factor 1
NUP188 nucleoporin 188kDa
NUP214 nucleoporin 214kDa
OAZ3 ornithine decarboxylase antizyme 3
OGDHL oxoglutarate dehydrogenase-like
OVGP1 oviductal glycoprotein 1, 120kDa
PCDHGA3 protocadherin gamma subfamily A, 3
PDCD2 programmed cell death 2
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDZK1IP1 PDZK1 interacting protein 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM14 PR domain containing 14
PRKCA protein kinase C, alpha
PRPF18 pre-mRNA processing factor 18
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGS12 regulator of G-protein signaling 12
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERHL2 serine hydrolase-like 2
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC25A30 solute carrier family 25, member 30
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SORBS1 sorbin and SH3 domain containing 1
SP100 SP100 nuclear antigen
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STYK1 serine/threonine/tyrosine kinase 1
TACSTD2 tumor-associated calcium signal transducer 2
TAS2R1 taste receptor, type 2, member 1
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBXA2R thromboxane A2 receptor
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM4 transglutaminase 4
TLDC1 TBC/LysM-associated domain containing 1
TMEM212 transmembrane protein 212
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRBC1 T cell receptor beta constant 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTLL3 tubulin tyrosine ligase-like family member 3
UBA6 ubiquitin-like modifier activating enzyme 6
ZC3H13 zinc finger CCCH-type containing 13
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTL8 actin-like 8
AHNAK2 AHNAK nucleoprotein 2
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAHD1 bromo adjacent homology domain containing 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF30 chromosome 11 open reading frame 30
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C3 complement component 3
CCDC132 coiled-coil domain containing 132
CDK18 cyclin-dependent kinase 18
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CENPO centromere protein O
CNR2 cannabinoid receptor 2 (macrophage)
CUL9 cullin 9
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DBF4B DBF4 zinc finger B
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DNAL4 dynein, axonemal, light chain 4
DNALI1 dynein, axonemal, light intermediate chain 1
EPPK1 epiplakin 1
ERCC5 excision repair cross-complementation group 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM53B family with sequence similarity 53, member B
FLJ22184
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AJ histone cluster 1, H2aj
HMG20A high mobility group 20A
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXB2 homeobox B2
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQCG IQ motif containing G
IQSEC2 IQ motif and Sec7 domain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD17 potassium channel tetramerization domain containing 17
KIAA0754 KIAA0754
KIAA0894 KIAA0894 protein
KLC2 kinesin light chain 2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMP3 lysosomal-associated membrane protein 3
LOC100287590 uncharacterized LOC100287590
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
N4BP3 NEDD4 binding protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NT5DC3 5'-nucleotidase domain containing 3
NXPH4 neurexophilin 4
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PCDHA6 protocadherin alpha 6
PCDHB13 protocadherin beta 13
PDE12 phosphodiesterase 12
PLEKHO2 pleckstrin homology domain containing, family O member 2
PODNL1 podocan-like 1
POMT2 protein-O-mannosyltransferase 2
PRAMEF11 PRAME family member 11
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
RNF2 ring finger protein 2
SAYSD1 SAYSVFN motif domain containing 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC41A3 solute carrier family 41, member 3
SLMO1 slowmo homolog 1 (Drosophila)
SMIM14 small integral membrane protein 14
SPEG SPEG complex locus
SPTBN2 spectrin, beta, non-erythrocytic 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
TBC1D2 TBC1 domain family, member 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEP1 telomerase-associated protein 1
TMEM120B transmembrane protein 120B
TMPRSS4 transmembrane protease, serine 4
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
UNKL unkempt family zinc finger-like
WDR33 WD repeat domain 33
WDR62 WD repeat domain 62
WDR78 WD repeat domain 78
XAB2 XPA binding protein 2
ZFP37 ZFP37 zinc finger protein
ZNF137P zinc finger protein 137, pseudogene
ZNF230 zinc finger protein 230
ZNF611 zinc finger protein 611